Developmental & Epileptic Encephalopathies - Medical / Health Care
DEEs are a heterogeneous group of rare and ultra-rare epilepsy syndromes that manifest with seizures, behavioral disturbances, or EEG abnormalities that can directly worsen cognition and behavior. These disorders are often progressive and are highly resistant to treatment.
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These syndromes involve:
- Impaired development (developmental encephalopathies)
- Regression of developmental progress (epileptic encephalopathies)
Examples of DEEs include early myoclonic encephalopathy, epileptic encephalopathy with continuous spike and wave during sleep, and certain syndromes including Ohtahara, West, Landau-Kleffner, Lennox-Gastaut, Doose and Dravet. Treatment of seizures or EEG abnormalities may improve the cognitive or behavioral deficits and reduce the seizures.
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