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Blood Brain Barrier Product Applications
6 applications found
More than 10 million people worldwide are living with Parkinson’s. Brain tumors and tumors of the central nervous system are the most common form of cancer in children under 19 and the leading cause of cancer-related deaths in children under 14 in the U.S. While antibody drugs have made great strides in cancer therapies, crossing the blood-brain barrier (BBB) and ensuring proper clearance from the brain have hindered the use ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
The trespassing of the blood brain barrier is a challenge for the treatment of central nervous diseases such as Alzheimer, Parkinson, stroke, or cancer (glioma). ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Kirkstall’s Quasi Vivo® system aims to establish and optimise a human in vitro 3D Blood Brain Barrier (BBB) in an effort to identify important mechanistic pathways for successful biomarker analysis, drug delivery and toxicity ...
ByKirkstall Ltd. based in York, UNITED KINGDOM
The delivery of therapeutical compounds such as RNA drugs into the brain presents the challenges of RNA preservation and the crossing of the blood brain barrier. Exosomes loaded with the specific siRNA sequences and marked with the neuron specific RVG peptide show specific accumulation in neurons, microglia and oligodendrocytes in the brain, effectively reducing genetic expression. This is a potential approach for ...
ByNanovex Biotechnologies based in Llanera, SPAIN
In this example, the aggregation of magnetic nanoparticles labeled with DiR is monitored in real time. Tumor microvasculature is labeled using ...
ByMauna Kea Technologies based in Paris, FRANCE
As targeted therapies evolve and the limitations of antibody-based therapies become clearer, a growing number of research teams are exploring the therapeutic potential of ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)