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Gene Editing Therapy Product Applications
14 applications found
Could you benefit from improved stability, dose control, or transduction efficiency? Are you looking to improve production yield? Albumin could be the natural ...
BySartorius AG based in Goettingen, GERMANY
Absence of a means for affordable and effective cell engineering hinders the commercialization of these advanced treatments. CellFE’s technology can get life-saving therapies to the patient at lower cost, with shorter manufacturing time, and higher retention of inherent ...
ByCellFE based in San Carlos, CALIFORNIA (USA)
Simple transfection solutions that are scalable and consistent from R&D through production are desired to eliminate variability along the development pipeline and reduce the cost of biomanufacturing. CellFE’s easy to use and scalable technology efficiently transfects any cell line without viruses or surfactants, using off-the-shelf ...
ByCellFE based in San Carlos, CALIFORNIA (USA)
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Assess the stability and quality of the next generation of biotherapeutics designed to treat cancer, immunize against pathogens, and address genetic disorders. Flow imaging microscopy detects aggregation of viral vectors such as AAVs, lentiviruses, and retroviruses as well as non-viral therapies like LNPs and ...
ByYokogawa Fluid Imaging Technologies, Inc. based in Scarborough, MAINE (USA)
A critical question in determining the mechanism of action of cell therapies is “do the cells go where you want them to?” Clinical cell tracking can answer this question and CellFE technology is uniquely suited for delivering of FDA-approved contrast agents to ...
ByCellFE based in San Carlos, CALIFORNIA (USA)
For many years, researchers have investigated cell and gene therapies as potential replacement therapies for severe chronic diseases. Despite major advancements in the field, these approaches carry a number of limitations including immune rejection, limited eligibility, durability and variability challenges, inability to re-dose and high manufacturing costs. To address these drawbacks, we developed our novel Shielded Living Therapeutics™ (SLTx) platform, which we believe has the potential to result in ...
ByEli Lilly and Company based in Indianapolis, INDIANA (USA)
We adapted an autologous ex-vivo gene therapy method to load the patient’s own TEMs precursors, that are hematopoietic stem and progenitor cells (HSPCs), with an immunotherapeutic transgene sequence. By re-introducing gene-modified HSPCs into the patient, we seek to take advantage of the self-renewing and multi-differentiation capability of HSPCs to enable durable and potentially long-term effects following a single ...
ByGenenta Science based in Milano, ITALY
The use of genetic material as therapeutic compounds to adjust dysfunctional cell behaviors is a revolutionary approach that has gained more attention in recent years in the medical field. Up or downregulation of genetic expression leads to an increased or decreased production of proteins respectively. The main challenge that gene therapy faces with naked genetic material is the low transfection rates and thus, therapeutic efficacy. Their physical properties as big sizes and polarity, difficult the permeation ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Maximize the probability of your clinical trial success by accelerating patient enrollment and flexible operations. Whether it is investigator-initiated study, observational study, phase 0, 1, 2, 3, or 4 post-market trials, real-world evidence generation to supplement your randomized controlled clinical trial, maximizing the speed of patient enrollment is the proven way to minimize your ...
ByJeeva Informatics Solutions Inc. based in Manassas, VIRGINIA (USA)
Save 70% of your time and maximize the probability of success of your clinical study. Avoid common pitfalls by starting your cohort study, patient registry, observational data collection, or clinical trial on Jeeva eClinical cloud platform. Save over 70% of the effort involved in toggling between numerous tools, coordination between multiple channels of engagement between study team and participants, participants use their own mobile device, and study specific data governance. ...
ByJeeva Informatics Solutions Inc. based in Manassas, VIRGINIA (USA)
CROs can differentiate their services to sponsors with the white-labeled Jeeva eClinical technology platform advantage. Maximize the probability of winning contracts with sponsors by differentiating your proposals with Jeeva eClinical cloud. Sponsors want to know how you can ensure faster patient recruitment and better retention compared to your peers. Jeeva can rapidly turnaround with a budget proposal and branded material for inclusion in your response to sponsor RFPs and support you throughout the ...
ByJeeva Informatics Solutions Inc. based in Manassas, VIRGINIA (USA)
Laser Force Cytology (LFC) and Radiance label-free approach to cell therapy research and biomanufacturing has significant value in expediting the process, decreasing costs, and ensuring therapy effectiveness and quality. Radiance enhances the highly complex biomanufacturing process for cell therapies by providing new insights to cell therapy research and process development. Current process development assays are fraught with difficult and time-consuming steps requiring highly skilled scientists and bioengineers ...
ByLumaCyte, Inc. based in Charlottesville, VIRGINIA (USA)
Simple and robust determination of critical quality attributes in ...
Bylino Biotech AG based in Zurich, SWITZERLAND
Fast at-line determination of product quality and biological relevant status information on process ...
Bylino Biotech AG based in Zurich, SWITZERLAND