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27 applications found
Copy Number Variants (CNV) are a clinically important variant type to identify in both somatic and germline genomes. NGS workflows and analytics are increasingly able to resolve duplications, deletions, and other CNVs, alongside SNVs and Indels in a streamlined workflow. These detection algorithms rely on consistent coverage and reads across the genome to accurately identify copy number changes within the genome. However, GC rich regions, suboptimal capture and sequencing primers can impact resolution of CNVs ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
The modular fashion with which Affilin® ligands can be fused together makes creating multi-specific binders an easy task. Combined with varying linker lengths, composition, and orientation, plus the optional addition of further accessory modules, our Navigo experts build the designed molecules as previously planned on the drawing ...
ByNavigo Proteins GmbH based in Halle, GERMANY
Solid tumor-specific Affilin molecules are currently being evaluated as CAR-T ligands. Specifically, they were confirmed to be functionally expressed on the effector cell surface, mediate target cell-binding and effective target cell-killing in a dose-dependent fashion. Importantly they were just as effective as commonly used antibody ...
ByNavigo Proteins GmbH based in Halle, GERMANY
Oligonucleotide refers to a very short single or double-stranded fragment of nucleic acid that can be joined together to form a single-stranded biopolymers. Oligo Pools are customizable genomic research products polymerized from various oligonucleotide fragments, playing an important role in gene synthesis, next-generation sequencing, library preparation, and so ...
ByCD Biosciences - htDNA-chip® based in Shirley, NEW YORK (USA)
Metagenomics is the study of all microbial genomes present in an environment, from the bottom of the sea to inside our own bodies. If you have shotgun NGS sequencing data, Partek provides powerful, easy-to-use analysis tools to characterize microbial ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
Copy number variation (CNV) is a type of structural variation and it encompasses duplication or deletion events that affect a considerable section of the genome. Those events may be mirrored by changes in gene expression levels and are consequently involved in pathogenesis. Partek tools enable you to start with raw data, detect amplified or deleted regions, and interpret or integrate the data with other assays such as gene expression. ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
Meeting regulatory requirements and maintaining quality doesn’t have to take up a lot of valuable time. With the PCS, MVS, and Artel’s Services, clinical labs can streamline regulatory compliance, maximizing productivity. ...
ByArtel, Inc. by Advanced Instruments based in Westbrook, MAINE (USA)
The most comprehensive view of the genome to realize the future of precision ...
ByRoswell Biotechnologies Inc based in San Diego, CALIFORNIA (USA)
DNA sequencing refers to the analysis of the base sequence of specific DNA fragments, namely the arrangement of adenine (A), thymine (T), cytosine (C) and guanine (G). The emergence of rapid DNA sequencing methods can greatly promote the research and discovery of biology and medicine. At present, the lowest-cost and high-throughput next-generation sequencing is the most widely used. Next-generation sequencing technology, also known as high-throughput sequencing technology, solves the problem that first-generation ...
ByCD Biosciences - htDNA-chip® based in Shirley, NEW YORK (USA)
Because the BacVax method is based on genomic and structural vaccinology, any bacteria can be analyzed for targets. Our vaccines will be able to address bacterial infections that currently have no vaccine options available, and we are ready to fill that ...
ByBacVax, Inc. based in Phoenix, ARIZONA (USA)
Helping providers make insightful decision based on analysis of disparate data sources such as medical records, lab data, genomic data, literature etc. Enhanced by a massive 2million QA KnowledgeBase for making clinical co-relations generating novel insights and meaningful associations. ...
ByOptrahealth Inc based in San Jose, CALIFORNIA (USA)
Cancer is one of the leading causes of deaths in India and a major public health concern. It is estimated that there are around 1 million new cancer cases every year and as many as 5 lakh deaths occur annually. Around 71% of all cancer deaths in India occur in people 30 to 69 years of age, when adults are very productive. The burden of cancer is expected to further increase due to increase in life expectancy, heavy use of tobacco and other risk factors such as radiation, viruses, ...
ByinDNA Research Labs based in , INDIA
In the era of global information, traditional storage technologies have been slightly tested. DNA must realize reliable information encoding. Only when DNA becomes a viable competitor of traditional storage technology is the first step for DNA to realize information storage. The most important thing is to produce nucleotide strings cheaply and quickly. For DNA, it is composed of four different monomers, consisting of a deoxyribonucleic acid having a skeleton with phosphoric acid. First, DNA is a polymer biological ...
ByCD Biosciences - htDNA-chip® based in Shirley, NEW YORK (USA)
Overcome CRISPR delivery limitations with FluidFM: for multiplex genome editing and fast cell line development. The discovery of CRISPR-Cas9 for targeted gene engineering has revolutionized life sciences. Regardless of its broad introduction across many disciplines in biology, several challenges persist in editing cell lines, particularly for sensitive cells, or when multiple edits are required. FluidFM offers a unique in-vitro gene editing tool to improve the efficiency and applicability of CRISPR across a ...
ByCytosurge AG based in Glattbrugg, SWITZERLAND
Single cell RNA-Seq is revolutionizing the study of complex tissues and diseases. The powerful and easy-to-use tools in Partek® Flow® empower researchers to analyze their own single cell RNA-Seq ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
Gene expression is the most fundamental level at which the genotype gives rise to a phenotype. Whether you have RNA-Seq, qPCR or microarray data, Partek provides easy-to-use tools that guide you through the analysis process from start to finish within a point-and-click interface. With over 8,000 citations, see why our gene expression analysis tools are the most trusted in the genomics ...
ByPartek Incorporated based in Chesterfield, MISSOURI (USA)
At the end of 2019, a novel coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei Province of China. The severity and rapid spread of COVID-19 (caused by SARS-CoV-2), resulted in a global pandemic declared by the World Health Organization in March 2020. The virus has spread to more than 100 countries, including the United ...
ByNovavax based in Gaithersburg, MARYLAND (USA)
Locus has built an automated, generalizable platform that is systematically unlocking the power of bacteriophage and CRISPR-Cas3 across multiple therapeutic ...
ByLocus Biosciences, Inc. based in Morrisville, NORTH CAROLINA (USA)
Förster resonance energy transfer (FRET) is a phenomenon of non-radiative transfer of the optical excitation from an excited electronic level of one molecule, called the donor, to a resonant electronic level of another molecule, called the acceptor. In ...
ByEdinburgh Instruments - TECHCOMP Group based in , UNITED KINGDOM
Unlike conventional vaccination strategies, cancer vaccines are designed to mount responses against tumor-specific antigens, arising from somatic mutations specific to the cancer genome. They promise a highly tailored approach by targeting patient-specific ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS