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Maldi MSI in Drug Development - Chemical & Pharmaceuticals - Pharmaceutical
Researchers have found many uses for MALDI mass spectrometry imaging in the process of drug development:
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Visualizing the effects of new therapies by determining the precise distribution of drugs and drug metabolites in a tissue section
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Potential target identification of compounds in therapeutic pathways by comparing the biomolecular composition of healthy and diseased tissues
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Optimizing drug delivery mechanisms
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Predicting or understanding the mechanism of action of a drug’s toxicity
For pharmaceutical research and development, experimental protocols must be reproducible, robust, and easy-to-use. The proprietary spray technology of the HTX TM-Sprayer and M5 Sprayer guarantees a very fine, uniform, and consistent matrix coating crucial for high-resolution imaging and relative quantification of analytes.
