Solution for Active Clinical Trials - Medical / Health Care - Clinical Services

Study Overview:

LAANTERN is a prospective, multi-center registry that will include data collection up to 5 years to evaluate safety, Quality of Life (QoL), and procedural outcomes including local control failure rate, progression free survival, overall survival, and seizure freedom in up to 1,000 patients and up to 50 sites. The study is currently enrolling eligible patients who would like to participate.

Study Device and Procedure:

The LAANTERN Registry will use the NeuroBlate System, a minimally invasive robotic laser thermotherapy tool that uses MRI-guided laser energy to ablate brain lesions.

With NeuroBlate, the surgeon attempts to ablate (destroy) lesions, or abnormal tissue, in the brain.  Unlike traditional brain surgery, a procedure with the NeuroBlate System does not require a large opening in the skull.  Instead, doctors create a small hole in the skull, about the diameter of a pencil.  While the patient is in the MRI machine, the doctor guides a small laser device (probe) through the hole into the lesion.  The probe delivers laser light energy that heats and destroys the affected tissue.  Because the NeuroBlate System is MRI-guided, the neurosurgeon is able to visualize the specific area of the brain to be ablated.  The precise nature of the procedure helps to lessen the likelihood of harm to nearby healthy tissue.¹

Study Eligibility:

You may qualify to participate in this study if you are planning to undergo the NeuroBlate procedure.

You may be a candidate if:

• You are undergoing thermal therapy with the NeuroBlate System.
• You provide written authorization and/or consent per requirements.
• You are available for the required study follow-up.

To take the next step, please contact a study center for more information. Only a study doctor can decide if you are a candidate for the study.

Study Purpose and Follow-up:

This Registry is intended to further understand the performance and utilization of the NeuroBlate System in current standard of care and will collect baseline, procedural and follow-up data. If you qualify for the study and you decide to participate, you will be provided with questionnaires to complete after your procedure and you will have more contact with hospital staff regarding your well-being. Visits to the clinic will be done on an as-needed basis and as recommended by your doctor.