Target Enrichment with SRSLY and Twist Exome Panel - Medical / Health Care - Medical Monitoring

SRSLY NGS library preparation with twist exome panel enrichment for ctDNA SNP profiling. Cell-free DNA (cfDNA), found circulating in blood, originates predominantly from dying cells. In healthy individuals the vast majority of cfDNA derives from hematopoietic myeloid and lymph cells undergoing apoptosis. However, in individuals with cancer, a variable fraction of the cfDNA derives from tumor cells undergoing apoptosis and/or necrosis. This tumor derived fraction of cfDNA is known as circulating tumor DNA (ctDNA). The amount of ctDNA found in an individual with cancer depends on numerous parameters such as tumor growth rate, metastasis, and overall tumor size