California Prop65 list
1. Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC) is an active ingredient in Nabiximols, a specific extract of Cannabis that was
approved as a botanical drug in the United Kingdom since 2010 as a mouth spray for people with
multiple sclerosis to reduce neuropathic pain, spasticity, overactive bladder, and other symptoms.
Nabiximols (as Sativex) is available as a prescription drug in Canada. In 2021, Nabiximols was approved
for medical use in Ukraine.
2. Abiraterone acetate
Abiraterone acetate is sold under many brand names, one of them being Zytiga. It is a medication used
to treat prostate cancer. It is used in combination with corticosteroid for metastatic castration-resistant
prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC). It should
either be used following removal of the testicles or along with a gonadotropin-releasing hormone
(GnRH) analog. It is taken by mouth.
Bevacizumab is usually sold under the brand name Avastin. It is a drug used to treat different types of
cancers and a specific eye disease. For cancer, it is given by slow injection into a vein via intravenous and
used for cancers of colon, lung, glioblastoma, and renal-cell carcinoma. This drug is used as a first-line
therapy in many of these diseases. For age-related macular degeneration it is given by injection into the
eye (intravitreal). Bevacizumab has received approved for medical use in the United States since 2004. It
is listed on the World Health Organization's (WHO) List of Essential Medicines for its use in treating eye
Acetamide also known as ethanamide is an organic compound. It is the simplest amide derived from
acetic acid. It finds some use as a plasticizer and as an industrial solvent. Acetamide is considered as a
median between acetone, which has two methyl groups. Acetamide is a natural occurring mineral with
the IMA symbol: Ace. It is used as a plasticizer and an industrial solvent. Liqid acetamide is good solvent
with a broad range of applicability. Dielectric constant in Acetamide is higher than most organic
solvents, allowing it to dissolve its inorganic compounds with solubilities similar to that of water.
Acetamide has various uses in electrochemistry and the organic synthesis of pharmaceuticals, pesticides,
and antioxidants for plastics. It is a precursor to thioacetamide.
Tretinoin or all-trans retinoic acid (ATRA), is a drug used for the treatment of acne and acute
promyelocytic leukemia. For acne this drug is used for oral application to the skin as a cream, gel or
ointment. Whereas for leukemia, this drug comes in a tablet form to be taken by mouth for atleast three
months. For precautionary measures, the use of this drug during pregnancy is contraindicated due to
the risk of birth defects. This drug is in the retinoid family of medications. Tretinoin was identified in the
year 1957, and approved for medical use in the year 1962. It is on the World Health Organization's
(WHO) List of Essential Medicines. Tretinoin is easily available as a generic medicine. In 2018, it was the 294th most commonly prescribed medication in the United States, with approximately 1 million prescriptions
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