Growth and behaviour of bovine articular chondrocytes on nanoengineered surfaces: Part I
Surface modification, using biomaterials to mimic in vivo cell microenvironment, plays an important role in tissue engineering. Current work studies the growth and behaviour of primary bovine articular chondrocytes on layer-by-layer self-assembled nanofilms of 11 different biomaterials, including polyelectrolytes and proteins [poly(styrene sulphonate) (PSS), fibronectin, poly-L-lysine (PLL), poly-D-lysine (PDL), laminin, bovine serum albumin (BSA), chondroitin sulphate (CS), poly(ethyleneimine) (PEI), poly(dimethyldiallylammonium chloride) (PDDA), collagen and poly(ethylene glycol) amine (PEG-NH
Keywords: polyelectrolytes, proteins, layer-by-layer, self-assembly, multilayers, nanofilms, nanoscale, surface modification, primary bovine articular chondrocytes, nanofilm architectures, surface roughness, atomic force microscopy, cell seeding density, cell viability, cell metabolic activity, nanotechnology, nanoengineered surfaces, biomaterials, tissue engineering
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