Homologous Recombination-mediated Genome Editing Service

As a global leader in recombination-mediated genome editing service, Creative Biogene is dedicated to provide a number of services to achieve scientific results faster than ever before. We have a team of passionate and talented scientists who have years of experience and would work closely with you to provide help in reducing your workload while raising the visibility of your research. In addition, relying on Creative Biogene's proprietary technologies and mature platform, we offer microbial genome site-directed mutagenesis, gene knock out and Knock-in/replacement service for a broad range of microbes.

The recombineering is a highly efficient and versatile manner of scarless genetic engineering which has the various applications in pushing the boundaries of synthetic biology. The recombineering can modificate nucleotide-precise DNA at any desired position without limitation to restriction sites, since the sequence of the homology regions can be selected casually. Furthermore, the recombineering is appropriate for a diversity of application, for instance introducing of point mutations into open reading frames and insertion or deletion of DNA fragments.

Creative Biogene uses the recombinant suicide plasmids manner and Lambda Red (λ-Red) recombinase system to obtain genetic modification successfully. With the accumulation of technology and resource, microbe genomic reconstruction is achieved by interrupting, inserting or deleting genes on the microbial genome to achieve research and utilization of genes.