3D bioprinting Articles
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Fabrication And Characterization Of 3D Bioprinted Triple-Layered Human Alveolar Lung Models
Researchers from Nanyang Technological University and its Center for 3D printing (SC3DP) have developed a 3D printed a highly repeatable and scalable three-dimensional in-vitro alveolar lung model using our REGENHU bioprinter, that could be exploited for pathogen translocation studies and respiratory-related toxicological testing applications. The triple-cell layered lung model was realized ...
By Regenhu
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Cells isolated from donors with nonalcoholic fatty liver disease exhibit disease phenotypes in 3D bioprinted human liver tissue
Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) bioprinted liver tissue. The characteristics of donors from which the ...
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Fabrication Of In-Vitro Phenotypically Stable Engineered Articular Cartilage
Researchers from IRCCS Istituto Ortopedico Rizzoli and Indian Institute of Technology, Delhi (IIT) used their REGENHU bioprinters to fabricate an in vitro phenotypically stable engineered articular cartilage by embedding human bone marrow-derived stromal cells (hMSCs) in a cell-laden silk fibroin–gelatin (SF-G) bioink. The bioprinted constructs allowed the in vitro study of chondrogenic ...
By Regenhu
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LLNL Uses 3D Bioprinting to Produce Live Cells
On March 5, 2019, the Lawrence Livermore National Laboratory (LLNL) announced that their researchers have 3D printed live cells that are able to convert glucose to ethanol and carbon dioxide gas. The substance produced from this conversion resembles beer. This means that this newly developed technology can lead to highly efficient biocatalysis. According to LLNL’s announcement, the use ...
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3D-printed blood vessels in monkeys marks medical breakthrough towards artificial organs
A Chinese firm has made a major medical breakthrough by succeeding in developing 3D-printed blood vessels that have been successfully implanted into monkeys, which is a major step towards making artificial human organs possible in future. Sichuan Revotek is a Chinese biotechnology firm that developed a 3D bioprinter back in 2015 which prints using stem cell-based bio ink, and it has now ...
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BeadReady™ successfully storing cells for 3D biofabrication
Another fantastic publication highlighting one of the multiple applications Atelerix products have within the scientific research and development industry. Anastassia Kostenko , Che J. Connon, and Stephen Swioklo (2023), have successfully shown that Atelerix BeadReady™ is a simple, adaptable solution for room temperature cell storage in combination with biofabrication and how this can be ...
By Atelerix Ltd
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Modeling NAFLD using 3D bioprinted human liver tissue
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease, with a prevalence of 25% ...
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Modeling NAFLD using 3D bioprinted human liver tissue
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease in the western world, with an ...
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Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis
Publication Summary: Compound induced chronic liver injury can lead to initiation of profibrotic processes resulting in sustained production of growth factors and profibrotic cytokines where inflammation, tissue remodeling and repair pathways are activated simultaneously to counteract the injury. Evaluation of potential antifibrotic therapies are limited using conventional non-human animal ...
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Bioprinting Algae To Improve Tissue Oxygenation
Engineers often rely on Mother Nature to help solve difficult problems. After millions of years of evolution, living organisms such as plants, animals, and microbes have discovered how to survive in even the harshest of environments. Often times, organisms from different species are able to provide each other with the nutrients, resources, or protection that both need to prosper. We call ...
By Allevi, Inc.
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3D Bioprinting Of Prevascularised Implants For The Repair Of Critically-Sized Bone Defects
By combining different cell populations in a fibrin bioink, researchers from Trinity College Dublin, Royal College of Surgeons in Ireland and University of Illinois Chicago were able to sprout an in vitro microvessel network that was then exploited to prevascularise a 3D printed scaffold implanted in a critical size femoral defect using REGENHU bioprinter. This dual approach was observed to ...
By Regenhu
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Andy Slavitt: When it comes to AI, it is the best of times, worst of times story
AI is a topic that fuels the passions of healthcare entrepreneurs but is it also a distraction from where the real pain points in healthcare are? A panel discussion on AI at the J.P. Morgan Healthcare Conference wrestled with the issue. Artificial intelligence is the kind of topic that brings out the inner geek in all of us. There is so much excitement about its potential applications and where ...
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Long-term performance of implanted bioprinted human liver tissue in a mouse model of human alpha-1 antitrypsin deficiency
Publication Summary: Conventional cell therapy and tissue engineering approaches to treating liver diseases and injury are limited by low cell retention, poor engraftment, poor graft durability and complications including portal hypertension. Integration of next generation technologies such as 3D bioprinting is an essential step towards the clinical success of these promising approaches and has ...
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Bioinspired Hydrogel To Improve The 3d Printability Of Mechanically Demanding Tissues Such As Intervertebral Disc
Researchers from Albert-Ludwigs-Universität Freiburg im Breisgau, Université Claude Bernard Lyon 1, Universidad Central “Marta Abreu” de Las Villas and Johannes Gutenberg-Universität Mainz developed a 3d printable, bioinspired hydrogel composed of two different biopolymers, chitosan and cellulose nanofibers, through an environmentally friendly process by avoiding both ...
By Regenhu
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Cultured Protein: A Guide to Every Cell-Based Meat Startup in the World Right Now
The alternative protein market is on fire right now, estimated to be worth approximately $2.2Bn, and cultivated meat is expected to play an important role in the shift from traditional meat products. Experienced scientists are engaged in cellular agriculture with the aim of reducing animal-based agriculture’s negative impact on both the planet and the suffering of animals and at the same ...
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A human in vitro three-dimensional bioprinted liver tissue system can be used to model nutritional damage and protective effects of MSDC-0602K, a novel modulator of the mitochondrial pyruvate carrier (MPC)
Publication Summary: The growing global incidence of NASH mirrors the availability of nutrients. Over-nutrition also results in insulin resistance and type-2 diabetes, which are often co-morbidities associated with NASH and are known to drive more adverse outcomes. MSDC-0602K, a modulator of the mitochondrial pyruvate carrier (MPC), is in clinical trials as a potential treatment for NASH. ...
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SPACE BIO-3D PRINTING FROM HUMAN CARTILAGE TO THYROID GLAND IN RODENTS AND TO SPACE ARTIFICIAL MEAT
Space bio-3D printing from Human Cartilage to Thyroid Gland in Rodents and to Space Artificial Meat: SUNKYE Satisfies the Connection and Signal System of Bio-3D Printing in Micro-gravity Environment Space bio-3D printing may be a concept we've heard recently. But as with 3D printing technology, there was only a short accumulation before it happened! Do we need Space bio-3D printing? Can't we ...
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IMCAS Americas 2019 Shined in Sunny Cartagena
The third annual IMCAS Americas, held in Cartagena, Colombia in August, attracted a motivated crowd of more than 900 delegates from 30 countries who came to learn and network with colleagues and key opinion leaders. “The congress faculty featured 110 international experts leading 85 scientific sessions for a total of 88 hours of scientific learning dedicated to the most important topics in ...
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