Allergic Inflammation Articles & Analysis
3 articles found
It is well-known for its role in promoting type 2 immune responses, such as allergic diseases. In 2021, a monoclonal antibody targeting TSLP was approved for the treatment of severe asthma. ...
Recently, in a study published in Cell Reports entitled "GM-CSF production by non-classical monocytes antagonistic controls LPS-driven functions in allergic inflammation," scientists from the University of Alabama and other institutions found through the study that the key to LPS promoting or preventing the body's anaphylaxis lies in the allergen itself. ...
The acute phase of AD occurs at the onset of Th1-cell activation.12 Also, Th17 cells play a role in the development of AD, acting as an initial cytokine source for the development of skin lesions.13 In AD patients, transepidermal water loss (TEWL) increases due to defects of the intercellular lipid bilayers in the stratum corneum.14 TSLP-stimulated dendritic cells (DCs) induce differentiation of ...