alzheimer disease Articles
-
Understanding the Stages: Preclinical Alzheimer`s Disease
Many neurological diseases, including Alzheimer’s disease, can be thought of as continuums, whether the presence and manifestation of the disease are different depending on the stage of the disease. In this article, we provide a high-level overview of the stages in the Alzheimer's disease continuum, with a focus on preclinical Alzheimer’s disease and its importance in patient care and ...
-
A Review of Therapies For Alzheimer's Disease
Alzheimer's disease (AD) is a progressive, irreversible neurodegenerative disease clinically manifested by cognitive impairment, behavioral abnormalities, and social deficits. It is predicted that by 2050, the number of people 65 and older with dementia in the United States could reach 13.8 million. In China, more than 15.07 million elderly people aged 60 or over suffer from dementia, of which ...
-
Nano-Flow Cytometry: A Revolutionary Tool for Biomedical Research
Nano-flow cytometry is a revolutionary technology that has the potential to transform early disease detection and diagnosis. Nano-flow cytometers are able to detect and analyze individual nanoparticles, including extracellular vesicles and viruses, with high sensitivity and accuracy. This makes them ideal for detecting diseases at their earliest stages, when they are most treatable. How does ...
-
TPD Show Potential For The Treatment of Alzheimer's Disease
Targeted protein degradation (TPD) is a promising strategy in the field of drug discovery. In recent years, targeted protein degradation (TPD) technology has developed rapidly, especially proteolysis targeting chimera (PROTAC), which is the most representative technology of TPD strategy. TPD drugs are one of the hot spots of new drug development in recent years, especially in the field of ...
-
Altoida Celebrates Historic Day for Patients with Alzheimer’s Disease
Today marks a historic day for all the scientists and researchers who have dedicated their lives to advancing our understanding of Alzheimer’s Disease over the last 20 years. For the more than 6 million individuals living with Alzheimer’s disease in the US, their families, and their caretakers, our team at Altoida celebrates the positive topline data reported on the CLARITY AD global ...
-
How Is Frontotemporal Dementia Different From Alzheimer`s?
People living with frontotemporal dementia, or FTD, are commonly misdiagnosed with psychiatric disorders or Alzheimer’s disease and other causes of dementia, such as Parkinson’s disease and vascular dementia. While frontotemporal dementia and Alzheimer’s disease can both cause dementia, there are distinct differences in impacted regions of the brain and, consequently, ...
-
Evolutionary, Medical, and Clinical Applications of Whole Exome Sequencing
As we all know, proteins play important roles in human bodies since all physiologic events are related to the structural or mechanical functions of certain proteins. Studying the synthesis process of proteins is a way to study the etiology, pathophysiology, diagnosis, and treatment of certain diseases. The human genome contains approximately 3 billion base pairs of DNA. Among them, only about 30 ...
By CD Genomics
-
The Mode of Action of Basic Proteins Involved in Cancer and Alzheimer's Disease Found
These proteins belonging to the HAT family are essential for life because they transport amino acids to the cell membrane. Although members of the family are nearly identical, they selectively transport certain amino acids. This specificity determines their involvement in specific functions, such as cell growth or neuronal function, and consequently in related diseases, such as cancer or ...
-
Nature: Structure-based classification of tauopathies
Abnormal accumulation of misfolded tau in filaments is characteristic of many neurodegenerative diseases—precisely for this reason, these neurodegenerative diseases are collectively referred to as tauopathy. The Michel Goedert team and the Sjors Scheres team at the Molecular Biology Laboratory of the Medical Research Council in Cambridge, UK, witnessed the use of cryo-EM to dissect tau ...
-
descriptors Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer’s disease and related tauopathies
Over time, genetic research have recognized a number of genetic danger variants related to neurodegenerative problems and helped reveal new organic pathways and genes of curiosity. Nevertheless, genetic danger variants generally reside in non-coding areas and should regulate distant genes reasonably than the closest gene, in addition to a gene’s interplay companions in organic networks. ...
-
Enzymes Used for Producing Homocysteine Assay Kit: Unlocking the Secrets of Homocysteine Detection
Homocysteine, an important biomarker in the field of clinical diagnostics, plays a significant role in assessing cardiovascular disease risk, vitamin deficiencies, and genetic disorders. Accurate and sensitive detection of homocysteine levels is crucial for early intervention and personalized patient care. In this article, we delve into the fascinating world of enzymes for producing the ...
-
Alzheimer’s and Parkinson’s Disease: A Breakdown of the Differences and Similarities
Alzheimer’s and Parkinson’s disease are both neurological diseases that cause progressive damage to the brain, resulting in a decline in neurocognitive function. While Parkinson’s disease is known for affecting movement and function and Alzheimer’s disease is known for affecting cognition, they are a bit more complex than that. Below, we provide an overview of ...
-
LncRNA Sequencing Helps to Find Deep Links to Disease
Long non-coding RNAs (lncRNAs) are a class of RNAs that do not code for proteins and are typically greater than 200 nucleotides in length. Studies have shown that lncRNAs are quite complex in function and play an important role in various biological processes such as development, differentiation, proliferation, metastasis, apoptosis, stem cell pluripotency, and DNA damage. Therefore, those ...
By CD Genomics
-
Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of respiratory diseases, numerous models have been developed, with a prominent ...
-
Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of respiratory diseases, numerous models have been developed, with a prominent ...
-
Exploring the Multifaceted Applications of Ox Bile Extract Powder
Introduction: Ox bile extract powder, derived from ox bile, is a natural product with a wide range of applications. It contains essential components such as bile acids, cholesterol, bilirubin, and fatty acids. Through meticulous preparation processes, it is transformed into a powdered form, enhancing its stability and convenience. Ox bile extract powder exhibits diverse applications in the fields ...
-
Noise and its Link to Mental Health
Today marks World Mental Health Awareness Day, and it’s one of the most important awareness events of the year. In the last few years, mental health awareness has dramatically improved, meaning that people who for too long have suffered in silence, are now getting the help and treatment they need. Several recent studies have shown a strong link between exposure to excessive noise levels ...
-
Why participants are so important to health research
Health research is very important for improving health care for all. As we mentioned in a previous article, What is Health Research?, this type of research helps medical researchers understand people’s health and how we can make treatments better for everyone. But health research isn’t possible without the contributions of research participants. Research participants are ...
By Evidation
-
Do you really have to sacrifice MRI image quality for speed?
To understand the significance of the SpinTech MRI STAGE software platform, it helps to begin by asking a question: Given that MRI is an incredibly powerful diagnostic tool for neurological diseases like Alzheimer’s, dementia, Parkinson’s and multiple sclerosis (MS), why have radiologists and neurologists had to choose between conducting faster MRI exams and obtaining higher-quality ...
-
Understanding Drug-Disease Relationship Analysis: A Key to Drug Discovery
In the realm of modern medicine, the quest for new and effective drugs to combat various diseases is a continuous journey. Drug discovery, the process of identifying compounds that can potentially treat diseases, has seen a significant transformation in recent years, thanks to advancements in computational biology and artificial intelligence (AI). In this article, we will delve into the ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you