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Analytical Chemistry Articles & Analysis

10 articles found

Glycan Cartography Mapping the Uncharted Territories of Cell Communication   

Glycan Cartography Mapping the Uncharted Territories of Cell Communication  

A single missing fucose residue can enhance antibody-dependent cellular cytotoxicity by 50-fold, revolutionizing cancer immunotherapy approaches. The analytical challenge is immense. Modern N-glycan analysis employs sophisticated orthogonal techniques including permethylation analysis, exoglycosidase arrays, and ion mobility-mass spectrometry to decipher isomeric structures ...

ByCreative Proteomics


GMP Cell Bank Characterization: Ensuring Quality and Safety in Biopharmaceuticals

GMP Cell Bank Characterization: Ensuring Quality and Safety in Biopharmaceuticals

Microbiological Testing: This includes sterility testing and mycoplasma detection to ensure that the cell bank is free from contamination. Analytical Chemistry: Methods like HPLC (High-Performance Liquid Chromatography) and mass spectrometry can be used to analyze secreted products, confirming the functional characteristics of the cells. ...

ByCreative Bioarray


What Does Glycosylation Impurities Detect?

What Does Glycosylation Impurities Detect?

Glycosylation impurities are a type of chemical commonly encountered in biochemical, medical, and pharmaceutical chemistry research. The presence of these impurities can affect the efficacy, safety, and stability of drugs. ...

ByMtoZ Biolabs


Native Porcine Prolidase: Bridging the Gap between Physiology and Industry

Native Porcine Prolidase: Bridging the Gap between Physiology and Industry

The versatility of Native Porcine Prolidase extends to the field of analytical chemistry as well. The enzyme is employed in the development of novel diagnostic tools and analytical methods, particularly in the detection and quantification of proline-containing compounds. ...

ByCreative Enzymes


Stability Analysis: A Meaningful, Impactful and At-the-Forefront Tool for Pharmaceutical Science

Stability Analysis: A Meaningful, Impactful and At-the-Forefront Tool for Pharmaceutical Science

Pharmaceutical Analysis Pharmaceutical analysis is a branch of analytical chemistry that deals with the analysis of pharmaceutical substances, including drugs, their formulations, and their compatibility with various excipients. This field is critical for ensuring the quality and safety of medicines, as well as for meeting regulatory requirements. ...

ByCD Formulation


Everything You Want to Know About Horseradish Peroxidase

Everything You Want to Know About Horseradish Peroxidase

Special chromatographic purification techniques are used to remove isozyme B which can affect immunological reactions. (2) RZ > 2 activity > 180 u/mg is mainly used in clinical chemistry, but some of the customers have also used this size product in immunological studies. At this point, a standardized analytical method becomes particularly important. 3) RZ ...

ByCreative Enzymes


Steno Diabetes Center Copenhagen - Metabolomics analysis with the Genius Series - Case Study

Steno Diabetes Center Copenhagen - Metabolomics analysis with the Genius Series - Case Study

Peak Scientific's quality, reliability and great customer service has prompted Steno to choose Peak gas generators for their labs. For more than 84 years Steno Diabetes Center has been run as a hospital, specialised in patient care, research, and prevention of diabetes, and in education of healthcare professionals within diabetes. Their ambition is to improve the entire field within diabetes in ...

ByPEAK Scientific Instruments Ltd


3 Reasons for Biopharmaceutical Labs to add Mass Detection to Routine Analyses

3 Reasons for Biopharmaceutical Labs to add Mass Detection to Routine Analyses

As regulators focus in on the critical quality attributes (CQAs) of biotherapeutics, what can biopharmaceutical labs in late development or QC do to increase confidence in their bioseparations assays – other than to run additional orthogonal assays? Many labs are finding the answer in mass detection, specifically with the ACQUITY QDa Detector from Waters. Here are three ways that mass ...

ByWaters Corporation


International scientists' priorities for research on pharmaceuticals and personal care products in the environment

International scientists' priorities for research on pharmaceuticals and personal care products in the environment

To expand that analysis we developed a survey that was completed by 535 environmental scientists from 57 different countries, of whom 49% identified environmental or analytical chemistry as their primary disciplinary background. They ranked the 22 original research questions and submitted 171 additional candidate research questions they felt were also of high ...

ByJohn Wiley & Sons, Ltd.


Nitrogen analysis of pharmaceutical excipients

Nitrogen analysis of pharmaceutical excipients

Customer: Butterworth Laboratories, United Kingdom Wilh nearly 40 years' experience, Butterworth Laboratories remains an independent UK con¬tract analytical service providing Method Development, Method Validation, Stability Testing and OC Testing to the pharmaceutical, medical device and chemical industries. They work in part¬nership with clients who not only recognize ...

ByBUCHI

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