anti-inflammatory Articles
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Epidermal growth factor-like domain repeat of stabilin-2 recognizes phosphatidylserine during cell corpse clearance
Exposure of phosphatidylserine (PS) on the cell surface occurs early during apoptosis and serves as a recognition signal for phagocytes. Clearance of apoptotic cells by a membrane PS receptor is one of the critical anti-inflammatory functions of macrophages. However, the PS binding receptors and their recognition mechanisms have not been fully investigated. Recently, we reported that stabilin-2 ...
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Chloroquine diphosphate
Chloroquine (diphosphate) is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis. Chloroquine is an inhibitor of autophagy and toll-like receptors (TLRs). MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and ...
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Anti-HIV and anti-inflammatory action of iodine-lithium-α-dextrin is accompanied by the improved quality of life in AIDS patients
Clinical efficacy, tolerability and safety of various doses of Iodine-Lithium-α-Dextrin (ILαD) monotherapy have been evaluated in 56 HIV-infected patients enrolled in double blind uncontrolled randomised study during 48 weeks follow-up period. ILαD was administered intravenously three times over five days with intervals of 23 weeks between treatments for a total of 12 infusions in 4 cycles. HIV-1 ...
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Introduction of Plant Extract for Personal Care Industry
1 Active ingredients of plant extract 1.1 Alkaloid Alkaloid, or plant alkaloid, is a alkaline nitrogen-containing organic compound and it is an active ingredient in Chinese herbal medicine. It is colorless and odorless and generally insoluble in water. 1.2 Flavonoid Flavonoid is widely found in various parts of plants, especially flowers and leaves. It has a variety of biological activities ...
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Occurrence and behaviour of chiral anti‐inflammatory drug naproxen in an aquatic environment
The present study reports on the occurrence and chiral behavior of the anti‐inflammatory drug (S)‐naproxen (NAP), (S)‐2‐(6‐methoxynaphthalen‐2‐yl)propionic acid, in an aquatic environment under field and laboratory conditions. (S)‐NAP was detected in influents and effluents of sewage treatment plants (STPs) located in the Tama River basin Tokyo at concentrations of 0.03–0.43 µg L−1 and ...
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Structural model of polymeric nanospheres containing indomethacin ethyl ester and in vivo antiedematogenic activity
The aim of this work was to establish a structural model for describing the organisation, at a molecular level, of nanospheres prepared by nanoprecipitation using poly(ε-caprolactone), sorbitan monostearate and polysorbate 80. Therefore, different techniques were employed to characterise the systems such as dynamic and static light scattering, small angle X-ray scattering and release profile ...
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Study of the pathogenic mechanisms of autoimmune myasthenia gravis - Case Study
Contexte Myasthenia gravis (MG) is an autoimmune disease caused by the presence of antibodies directed against components of the muscle membrane located at the neuromuscular junction. In the majority of cases, these are autoantibodies directed against the acetylcholine receptor (AChR). The origin of the autoimmune response is not known, but thymic abnormalities and defective regulation of the ...
By Inovarion
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Effect of combined Low-Dose Radon- and Hyperthermia Treatment (LDRnHT) of patients with ankylosing spondylitis on serum levels of cytokines and bone metabolism markers: a pilot study
Ankylosing Spondylitis (AS) is a rheumatic disease and almost 50% of the affected patients suffer from osteoporosis. The ratio of Receptor Activator of Nuclear Factor κB Ligand (RANKL) and Osteoprotegerin (OPG) has become an important marker to assess the status of systemic bone metabolism and has been shown to be dysregulated in AS patients. Combined Low-Dose Radon- and Hyperthermia Therapy ...
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Plasma medicine: Using cold atmospheric pressures in dermatology
The research of atmospheric plasma’s use for medical treatments has gathered apace over recent years. Plasma comprises charged particles as well as a range of other active components that are thought to interact with the body to produce desired affects in plasma medicine such as; electric current, UV radiation and reactive gas species these components are thought to be able to act ...
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Development of fabrication technique in nano–scale resveratrol by collagen
Resveratrol (3,5,4′–trihydroxy–trans–stilbene, RSV), is found in various plants, including grapes, berries and peanuts. It is also present in wines, especially red wines. RSV has potent antioxidant, anti–inflammatory, and chemo–protective properties used as a biologically active supplement in the prophylaxis of myocardial infarction, diabetes, and tumours. The aim of this study was using ...
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Research Progress of Tetrahydrocurcumin
Tetrahydrocurcumin (THC), as the most active and main metabolite produced in the metabolism of curcumin in vivo, can be isolated from the cytoplasm of the small intestine and liver after curcumin administration in human or mouse. Tetrahydrocurcumin can effectively inhibit tyrosinase, inhibit the generation of Oxygen Free Radicals and scavenge the formed free radicals. It has obvious antioxidant ...
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Inflammatory Cytokines Profile
Cytokines are classified according to their different roles in the inflammatory response: pro-inflammatory cytokines and anti-inflammatory cytokines. Pro-inflammatory Cytokines Interleukin-1 (IL-1) IL-1 is a proinflammatory cytokine that activates a variety of immune and inflammatory cells and is secreted mainly by monocytes/macrophages, neutrophils and endothelial cells. IL-1 consists of two ...
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AstaPure® EyeQ: Natural astaxanthin for Eyes and brain - Download the eBook!
Inspired by the superb vision and natural mechanism of the eagle's eye, Algatechnologies introduces AstaPure® EyeQ. a clinically supported, microencapsulated, cold water-soluble 2% natural astaxanthin powder. AstaPure® EyeQ is a highly pure extract derived from Haematococcus pluvialis microalgaer a species of microalgae known to be the richest source of natural astaxanthin. As a ...
By Algatech
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Fermented Raw Material for Cosmetic Skincare Product
The cosmetics and skincare industry is constantly evolving and a recent trend that has emerged is the use of fermented ingredients in skincare products. Fermentation is a microbial metabolic process that has been used for centuries in food and beverage production, and now it has been extended to the cosmetic industry.What are Fermented Raw Materials?Fermented raw materials are natural ingredients ...
By BOC Sciences
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Cytokines in CAR-T Cell Therapy
What is CAR T-cell therapy? Car-t cell therapy involves genetically engineering T cells isolated from patients or allogeneic donors to express chimeric antigen receptors (CAR) that specifically recognize and kill tumor cells. As a "living" drug, CAR-T therapy is very different from traditional drugs. It is a new type of precision targeted therapy for the treatment of tumors. Compared with ...
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Symberix Featured in Nature
Durham, NC (February 3, 2020) - An article in Nature highlights Symberix's efforts to understand the complex relationship between drugs and the microbiome. The paper discusses recent contributions to the emerging field of “pharmacomicrobiomics” -- the study of how microbes impact drug disposition, efficacy, and toxicity. Symberix is developing bacteria-targeted small molecules that ...
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Too much sugar consumed at a young age can harm the brain and lead to mental disorders
Sugar is a direct source of sweetness that not only enhances the flavor of food but also serves as a source of energy for the body. Sugar is used in everyday life to give us a "sweet" feeling, whether it's in candy, cake, or cola. Sugar consumption is quickly increasing as material living standards rise, which not only leads to an increase in obesity rates, but also increases various health ...
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A Quick Guide to Proteolytic Enzymes
Protease formulations are without a doubt one of the most fully functional dietary supplements in terms of providing significant health benefits. Clinical studies have documented numerous effective benefits and support for people facing a variety of health challenges, including: a) Asthma b) Atherosclerosis c) Autoimmune disease d) Bronchitis e) Cancer f) ...
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Alleviation of DSS-induced colitis via Lactobacillus acidophilus treatment in mice
Abstract Gut microbiota play a major role in host physiology and immunity. Inflammatory bowel diseases (IBDs), the important immune-related diseases, can occur through immune system malfunction originating due to dysregulation of the gut microbiota. The aim of this study was to investigate the capabilities and mechanisms of Lactobacillus acidophilus (L. acidophilus) KBL402 and KBL409 treatment ...
By KoBioLabs
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5 Things You Can Do in 2022 for Better Heart Health!
Even if heart health isn’t your top concern in the new year, you can’t go wrong staying on top of your cardiovascular wellbeing. Sadly, heart disease is the leading cause of death in the United States, according to the Centers for Disease Control (CDC). And a recent study found that 40% of adults between the ages of 50 and 64 without a heart-disease diagnosis still had early signs of ...
By BIOLIFE4D
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