antigen delivery Articles
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The preparation and characteristic of poly(lactide co–glycolide) microspheres as novel antigen delivery systems
Polymeric microspheres with encapsulated antigens or medicine have become well established in the last decade as potent delivery systems. Our novel PLGA microspheres were prepared using a w/o/w solvent evaporation process in the presence of the anionic surfactants, including poly–L–lysine (PLL), cetyltrimethylammonium (CTAB), polyethyleneimine (PEI). High lamellae incorporation efficiency (97%), ...
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The nanovaccine technology with huge potentials
Vaccines are an unparalleled medical milestone that has saved countless lives by harnessing the human immune system, according to the history of human development. Vaccine remains the most effective source of defense against the COVID-19 pandemic since 2020. The success of the lipid nanoparticle COVID-19 mRNA vaccine shows that nanotechnology can be used in vaccine development. Compared to ...
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Applications of Liposomal Drug Delivery System Technology
Liposomes are a novel drug delivery system (DDS). They are bimolecular vesicles that form spontaneously when phospholipids are dispersed in water. Liposomes vary in size, composition and charge and can be used as carriers for a wide range of drug molecules, such as chemotherapeutic agents, antimicrobial and antiviral drugs, antiparasitic drugs, genetic material, vaccines, therapeutic proteins, ...
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Vaccine Projects
Abera’s vaccine delivery platform works as a plug-and-play system where known or novel antigens can be engineered onto our delivery platform to create effective, multivalent vaccines that are cost-effective and fast to produce. We actively work together with academia and industry to enable the use of our vaccine delivery platform in design and development of new vaccines. Many of these ...
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Antibody-peptide epitope conjugate (APEC), another disguise for ADC
Background Tumor immunotherapies compose immune checkpoint inhibitors, therapeutic antibodies, tumor vaccines, cellular therapies, and so on. However, each has its own set of issues, such as the fact that CAR-T therapy is an individual therapy that is costly; immune checkpoint inhibitors are highly effective, but only in some patients. The researchers expose us to a radically different way of ...
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Peptide Vaccine Design
Vaccines are considered one of the most successful medical interventions in the past few centuries, aiming to harness the human immune system and generate lasting protection against specific diseases. Traditional vaccines rely on the use of inactivated pathogens to trigger an immune response. However, many of these formulations carry a high risk of causing allergies or autoimmune reactions. ...
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