Antigen Design Articles & Analysis: Older
5 articles found
In biomedical research, antibodies are a powerful tool used in the detection and quantification of target antigens. However, a comprehensive understanding of the antibody requires knowledge of its amino acid sequence, which can be achieved through antibody sequencing.Antibody sequencing is a nucleic acid sequencing process that determines the nucleotide sequence of the gene ...
This epitope might show high similarity or significant differences in sequence across different species.From a purely practical perspective, compared to other forms of antigens, the synthesis of peptides also has the advantages of being simple, fast, and inexpensive.The Key to Designing the Right PeptidesPeptides have long been the preferred ...
Linkers play a crucial role in the design of conjugated drugs, as they determine the stability, release kinetics, and overall efficacy of the conjugate. BOC Sciences offers a variety of linkers, including cleavable linkers, non-cleavable linkers, and pH-sensitive linkers, to accommodate different drug payloads and target antigens. These linkers are ...
Why target GPCRs with antibodies? The G Protein-coupled receptor (GPCR) superfamily represents the largest and single most important family of human drug targets. GPCRs play a central role in a plethora of biological processes and are linked to a wide range of therapeutic areas including cancer, diabetes, inflammation, cardiovascular diseases, and chronic pain. Expressed in every type of cell in ...
Antibodies with catalytic activity can be obtained by using pre-designed antigens (haptens) according to the preparation procedures of general monoclonal antibodies. ...