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Antigen Gene Articles & Analysis
2 articles found
The principle is to clone one or several antigen genes of a pathogen into host cells, causing them to express the corresponding antigen protein. ...
We tested the potency of these compounds in altering the interaction of CTLA-4 with its ligands in a reporter cell system with effector Jurkat cells carrying a luciferase gene and antigen presenting Raji cells. Compounds binding to CTLA-4 blocked the interaction of CTLA-4 with its ligands and resulted in increased luminescent signal. ...