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Approved Peptide Drugs Articles & Analysis: Older

39 articles found

Liposomes in Drug Delivery: Progress, Limitations, and Future Prospects

Liposomes in Drug Delivery: Progress, Limitations, and Future Prospects

Liposomes, spherical vesicles composed of one or more phospholipid bilayers, have garnered significant attention in the field of drug delivery due to their unique properties. These nanocarriers offer a promising approach to overcome challenges associated with traditional drug administration, enhancing therapeutic efficacy while minimizing side effects. This article will delve into the role of ...

ByCreative Biostructure


How Predictive Analytics is Boosting Clinical Trials Efficiency?

How Predictive Analytics is Boosting Clinical Trials Efficiency?

Clinical trials are the backbone of modern medicine, responsible for bringing innovative, safe, and efficient treatments to market after rigorous testing and evaluation. However, the conventional process of conducting these trials has often been long, expensive, and fraught with inefficiencies¹. The advent of predictive analytics is reshaping the landscape of clinical trials, ushering in a ...

BySOPHiA Genetics


How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...

ByCreative Bioarray


An Overview of Isotopes

An Overview of Isotopes

What are Isotopes? Isotopes are different atoms of the same element with the same number of protons and different numbers of neutrons called isotopes of each other, which can also be interpreted as different nuclides of the same element called isotopes of each other. An isotope is one of two or more atoms of the same chemical element with the same atomic number, occupying the same position on the ...

ByBOC Sciences


Review of ADC Linker and Research Progress

Review of ADC Linker and Research Progress

The linker is not only the molecule part of the covalent link between the antibody and the small molecule payload, but also a key element with design properties in targeted drug therapy. The addition of the linker should not induce aggregation and needs to ensure acceptable PK characteristics, while limiting the premature release of the payload in plasma and enabling the effective release of ...

ByBOC Sciences


Do Peptide Drugs Need Acylation Blocking at Nα?

Do Peptide Drugs Need Acylation Blocking at Nα?

When the involved peptide is a depsipeptide (X=O in Figure 1), the formation of DKP is accelerated, as hydroxy derivatives act as better leaving groups than their amino counterparts.FDA-approved Peptide DrugsConsidering the common occurrence of degradation in peptides with Nα groups, whether the N-terminus should be blocked to ...

ByCreative Peptides


How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...

ByCreative Bioarray


Peptide Vaccine Design

Peptide Vaccine Design

Another strategy to enhance the peptide-MHC binding affinity is to stabilize peptides by adding β-amino acids to the epitopes.Enhancing Peptide Vaccine ImmunityImproving the immune efficacy of peptide vaccines can be achieved by modifying peptide size or binding properties, directly activating APCs or ...

ByCreative Peptides


The Role of Preserved Plasma in Improving Lives of Those with Bleeding Disorders

The Role of Preserved Plasma in Improving Lives of Those with Bleeding Disorders

Bleeding disorders, a collection of conditions that prevent blood from clotting correctly, can be life-threatening. They’re caused by issues such as aberrant platelets, abnormal clotting proteins, or problematic blood vessels. Understanding how blood clots normally can help elucidate why these disorders are so serious. In a standard clotting process, platelets, a type of blood cell, act ...

ByB Medical Systems


FDA Approved Peptide Drugs in the First Half of 2023

FDA Approved Peptide Drugs in the First Half of 2023

It is worth noting that the 26 drugs approved include 4 peptide drugs, accounting for 15% of the total. ...

ByCreative Peptides


Huateng Pharma Supplies Minoxidil Intermediate 2,4-Diamino-6-chloropyrimidine (CAS NO.156-83-2)

Huateng Pharma Supplies Minoxidil Intermediate 2,4-Diamino-6-chloropyrimidine (CAS NO.156-83-2)

Minoxidil was first introduced by Upjohn Company of the United States, and was first used as an oral drug for the treatment of refractory hypertension in the 1970s. In later clinical applications, doctors observed hair regrowth and generalized excessive hair in balding patients, which led to the development of minoxidil preparations. Minoxidil can increase local blood supply, stimulate the ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Leveraging Antibody Modeling Services to Accelerate Drug Discovery

Leveraging Antibody Modeling Services to Accelerate Drug Discovery

The discovery of antibody drugs is a rapidly developing field, and antibody modeling services offer reliable and efficient tools for their discovery and design. By predicting the interactions between antibody drugs and molecular targets, antibody modeling services can enhance the affinity and specificity of antibody drugs and reduce the development time and cost. In addition to antibody ...

ByCD ComputaBio


Virtual Screening: Revolutionizing Drug Discovery through Computational Intelligence

Virtual Screening: Revolutionizing Drug Discovery through Computational Intelligence

In the fast-paced realm of drug discovery, scientists constantly seek innovative approaches to efficiently and cost-effectively identify potential drug candidates. Virtual screening, a breakthrough computational technique, is poised to transform the pharmaceutical industry. In this article, we delve into the world of virtual screening and explore its remarkable potential to revolutionize drug ...

ByCD ComputaBio


ADC Drugs For HER2 Positive Breast Cancer

ADC Drugs For HER2 Positive Breast Cancer

According to the latest data, breast cancer has overtaken lung cancer to become the most common cancer among women, and the death rate is the second highest among female tumors, seriously affecting the physical and mental health of women around the world. Patients with abnormal expression of human epidermal growth factor receptor (HER2) account for 15%-20% of all breast cancers, which is highly ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Brief Introduction of ADC Drug Production Technology

Brief Introduction of ADC Drug Production Technology

Drug-to-antibody ratio (DAR, drug-to-antibody ratio) The number of cytotoxic drugs connected to each antibody is the drug-to-antibody ratio (DAR). When the DAR increases, the drug metabolism rate of ADC drugs increases, the half-life decreases, and the systemic toxicity increases. ...

ByBOC Sciences


ADC Drugs For Breast Cancer Treatment

ADC Drugs For Breast Cancer Treatment

On February 24, 2023, The NMPA approved Enhertu, an injectable drug developed jointly by AstraZeneca and Daiichi Sankyo, for the treatment of adults with unresectable or metastatic HER2-positive breast cancer who have previously received one or more anti-HER2 drugs. ...

ByBiopharma PEG Scientific Inc


Field Orthopaedics gets FDA approval for world’s smallest orthopaedic screw

Field Orthopaedics gets FDA approval for world’s smallest orthopaedic screw

The Brisbane-based designer of the world’s smallest orthopaedic screw has invoiced US hospital suppliers $900,000 in the three weeks since the device gained Food & Drug Administration approval, and he hopes it can soon be made in Brisbane too. Field Orthopaedics, founded in 2016 by former Army doctor Chris Jeffery alongside a team of doctors and engineers including hand surgeon Greg ...

ByField Orthopaedics


Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma

Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma

Carfilzomib, a proteasome inhibitor, is indicated for the treatment of patients with multiple myeloma. Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Altoida Celebrates Historic Day for Patients with Alzheimer’s Disease

Altoida Celebrates Historic Day for Patients with Alzheimer’s Disease

Today marks a historic day for all the scientists and researchers who have dedicated their lives to advancing our understanding of Alzheimer’s Disease over the last 20 years. For the more than 6 million individuals living with Alzheimer’s disease in the US, their families, and their caretakers, our team at Altoida celebrates the positive topline data reported on the CLARITY AD global ...

ByAltoida, Inc.


CanaQuest Medical Corp (OTC: CANQF)

CanaQuest Medical Corp (OTC: CANQF)

About: CanaQuest Medical is an award-winning, Clinical Stage/Life-Sciences company focused on the drug discovery and development of next-generation targeted therapeutics within the endocannabinoid system and specific brain receptors. The Company is focused on treating neurological conditions, such as epilepsy, anxiety, depression, and Post Traumatic Stress Disorder “PTSD,” including ...

ByCanaQuest Medical Corp.

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