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Artery Remodeling Articles & Analysis

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Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis

Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis

EC responses to fluid shear stress play major roles in vessel function, remodeling, and disease. Shear stress regulates artery remodeling to determine lumen diameter and during angiogenesis stabilizes vessel sprouts once flow is reestablished (10, 11). Disturbed flow patterns that arise in regions of arteries that curve sharply ...

ByJohnson Controls, Inc.

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