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Arthritis Articles & Analysis

57 articles found

ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

l Cystic fibrosis (CF): Neutrophilic inflammation in the CF lung is exacerbated by high ELANE levels, promoting mucus hypersecretion, airway remodeling, and bacterial persistence. l Rheumatoid arthritis and vasculitis: ELANE damages endothelial barriers and exposes autoantigens, further fueling immune activation. ...

ByCreative BioMart


Tissue Cross-Reactivity Studies: An Overview

Tissue Cross-Reactivity Studies: An Overview

For example, in conditions like rheumatoid arthritis or lupus, researchers can pinpoint which autoantigens share similarities with microbial antigens. ...

ByCreative Bioarray


Exploring Mouse Luminex Cytokine Assays: A Powerful Tool for Immune Research   

Exploring Mouse Luminex Cytokine Assays: A Powerful Tool for Immune Research  

Autoimmune Diseases: By analyzing cytokine imbalances, researchers can uncover mechanisms underlying diseases such as rheumatoid arthritis and lupus. Infectious Diseases: Cytokine panels provide insights into host-pathogen interactions and immune responses to infections. ...

ByCreative Proteomics


Discovering the Natural Pain Relief and Anti-Inflammatory Properties of Serrapeptase   

Discovering the Natural Pain Relief and Anti-Inflammatory Properties of Serrapeptase  

This property is particularly beneficial in managing conditions like arthritis, sinusitis, and post-surgical swelling. Pain Relief: Serrapeptase has analgesic properties that can alleviate pain associated with inflammation and tissue injury. ...

ByCreative Enzymes


Multi-Method Approaches for Collagen Quantification and Analysis

Multi-Method Approaches for Collagen Quantification and Analysis

The measurement of collagen can help researchers and physicians understand the pathological process of related diseases (such as osteoporosis, arthritis, skin aging etc.), and also aid in drug development and other biomedical research.The measurement of collagen can usually be carried out through several different methods:Mass Spectrometry1. ...

ByMtoZ Biolabs


TNC Protein: The Hidden Hero of Cellular Communication

TNC Protein: The Hidden Hero of Cellular Communication

By modulating inflammation, it could help restore balance in conditions like multiple sclerosis or rheumatoid arthritis. Uncovering the Secrets of TNC Protein Despite its importance, much about TNC protein remains a mystery. ...

ByCreative BioMart


From Lab to Market: The Journey of Monoclonal Antibody Development   

From Lab to Market: The Journey of Monoclonal Antibody Development  

They can usually be used to treat rheumatoid arthritis. These drugs are used to treat rheumatoid arthritis. Currently, researches on monoclonal antibody drugs development expand the range to immuno-oncology, targeted therapy, and immunotherapy. ...

ByAlfa Cytology


Hargreaves Test-A Brief Overview

Hargreaves Test-A Brief Overview

This trial assessed changes in the pain hypersensitivity response due to lumbar arthritis after PMM by the Hargreaves test. l The hind paw of the experimental animal was given a concentrated radiant heat stimulus and the animal was free to change position at any time to avoid the stimulus. ...

ByProtheragen


Nanobodies Definition, Structure, Advantages and Applications

Nanobodies Definition, Structure, Advantages and Applications

Another VHH domain binds to human serum albumin (HSA), and the drug is indicated for rheumatoid arthritis (RA). Ozoralizumab was developed by Ablynx, and Taisho obtained the development authorization from Japan. ...

ByBOC Sciences


Diabetomics Lumella - New Point-of-Care Blood Test Kit for Early Detection of Preeclampsia

Diabetomics Lumella - New Point-of-Care Blood Test Kit for Early Detection of Preeclampsia

Abstract Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of synovial joints. ...

ByDiabetomics, Inc.


CD19: One of The Most Important Targets for Car-T Cell Therapy

CD19: One of The Most Important Targets for Car-T Cell Therapy

Consequently, CAR-T cell therapy targeting CD19 has gained widespread use as a treatment for CD19-positive CLL, showing promising therapeutic outcomes. 3) Autoimmune Diseases: Autoimmune diseases stem from the immune system's attack on its own healthy tissues and organs. Conditions like rheumatoid arthritis and systemic lupus erythematosus involve abnormal activation and function ...

ByBeta Lifescience


Breakthrough Innovations in Bipolar Hip Prosthesis: Improving Mobility and Stability

Breakthrough Innovations in Bipolar Hip Prosthesis: Improving Mobility and Stability

Hip replacement surgery has been a life-changing procedure for individuals grappling with debilitating hip conditions like osteoarthritis, rheumatoid arthritis, or hip fractures. Over the years, continuous strides in medical technology have ushered in substantial enhancements in hip prostheses, offering patients the prospect of regaining mobility, alleviating pain, and improving ...

ByZealmax Innovations Pvt. Ltd.


How Much Do You Know about Cocklebur Plant?

How Much Do You Know about Cocklebur Plant?

Its distinctive fruit, covered with a tough shell and burrs, has been used for centuries in traditional medicine for headaches, nasal congestion, skin pigmentation disorders, tuberculosis-related diseases and rheumatoid arthritis. In recent years, scientists have explored its potential use in treating rheumatoid arthritis and cancer. ...

ByCD BioGlyco.


Cytokine Involvement in Inflammatory Immune Disorders

Cytokine Involvement in Inflammatory Immune Disorders

Cytokine Involvement in Rheumatoid Arthritis (RA) RA, an immune-related polyarticular inflammatory disorder, involves a spectrum of cytokines, including IL-1B, IL-6, IL-12, IL-15, and TGF-β. ...

ByCreative Proteomics


The Role of MMP-3: Insights into Disease Progression and Therapeutic Potential

The Role of MMP-3: Insights into Disease Progression and Therapeutic Potential

Clinical Applications of MMP-3 MMP-3 and Rheumatoid Arthritis (RA) Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial cell proliferation and infiltration of lymphocytes, leading to destruction of joint cartilage and bone erosion. ...

ByBeta Lifescience


Unraveling the IL-17 Family and its Receptor Complex: Key Players in Immune Responses

Unraveling the IL-17 Family and its Receptor Complex: Key Players in Immune Responses

Autoimmune disease target - IL-17 Family IL-17 plays an important role in promoting autoimmune diseases such as psoriasis, psoriatic arthritis, and ankylosing spondylitis (AS). Currently, five large-molecule biopharmaceuticals targeting IL-17/IL-17R are available worldwide, including four IL-17 monoclonal antibodies and one IL-17RA monoclonal antibody, namely ...

ByBeta Lifescience


Understanding IL-36 Cytokines: Their Role & Potential in Treating Inflammatory Diseases

Understanding IL-36 Cytokines: Their Role & Potential in Treating Inflammatory Diseases

In addition to being a target for skin inflammatory diseases, IL-36 can also be an effective drug target for inflammatory bowel disease (IBD), rheumatoid arthritis, and other inflammatory diseases. Related Recombinant Proteins Offered by Beta LifeScience IL-1 SuperFamily Human IL-1 alpha/IL -1F1 Biotinvlated Human IL-1 alpha/IL-1F1(C-Avi) Mouse IL-1 alpha/IL -1F1 Rat IL-1 ...

ByBeta Lifescience


What is FGL2?

What is FGL2?

FGL2 and disease Studies have found that FGL2 is highly expressed in microvascular endothelial cells, causing microcirculatory disturbance, promoting myocardial and liver ischemia-reperfusion injury, arthritis, type 2 diabetic heart failure, and type 2 diabetic nephropathy; FGL2 is highly expressed in inflammatory bowel disease mucosa , correlated with disease severity; in HCV, ...

ByCreative Diagnostics


Reducing Chronic Pain at a Processing Plant - CPG/Manufacturing - Case Study

Reducing Chronic Pain at a Processing Plant - CPG/Manufacturing - Case Study

Brian’s doctor told him he had arthritis in his knee. He tried medication and physical therapy, but his pain continued to ...

ByHinge Health, Inc.


Project - Sublingual IL2 (BL SLIT I)

Project - Sublingual IL2 (BL SLIT I)

These diseases include: Asthma Psoriasis Lupus Rheumatoid arthritis Multiple sclerosis ...

ByBioLingus AG

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