biobank Articles
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Project - SmartBIMS
“New technological components to allow interoperability and data analysis in biobanks” Call: EUROSTARS-2 (International Intercompany Action) Reference No.: E!114111 / CIIP-20202004 This project has received funding from the Eurostars-2 joint program with co-financing from the CDTI and the Horizon 2020 Research and Innovation Framework Program ...
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Being a member of the club: the transnational (self-)governance of networks of biobanks
Biobanks have become one of the core resources for biomedical research. At the same time, a number of risks associated with processing and storing of biological material and corresponding data have been diagnosed. This paper focuses on how institutionalised transnational networks of biobanks generate practical answers to some of these risks. Drawing upon three case studies – GenomEUtwin, ...
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MC3R Links Nutritional Status to Child Growth and Pubertal Timing
Scientists have determined how a protein in the brain uses information about the body's energy balance to regulate children's growth rate and the onset of puberty. The study focuses on the melanocortin 3 receptor (MC3R), a member of the protein family, which has long been thought to play an important role in metabolism and energy balance. Roger Cone, a physiologist at the University of ...
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Cryopreservation Process, Methods and Storage Solution Explored
The Cryopreservation Process The Cryopreservation Process is where biological matter (cells, tissue, organs, etc) is preserved by cooling to a very low temperature. This process stops the normal cell functions and holds the sample in suspended animation. When the time comes to thaw the sample, normal biological function resumes.Cryopreservation Process Steps The cryopreservation process can be ...
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The Danish National Genome Center Partners with Lifebit to Deliver Nationwide Personalised Medicine
The Danish National Genome Center has awarded Lifebit a four-year contract to implement Lifebit’s Federated Trusted Research Environment software, Lifebit CloudOS, within Denmark's national supercomputing center. LONDON, UK - 28 April 2022 – Lifebit, whose leading technology enables secure analysis over sensitive datasets for researchers and interconnects such large patient cohorts ...
By Lifebit
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Biorepository Safety
What is a Biorepository? A biorepository, or "biobank", is a specialized facility designed to store, archive, and distribute biological samples for research or clinical purposes. Biorepositories house biological samples, such as blood, plasma, urine, saliva, tissues, DNA, and organs, among other specimen types, collected from consenting individuals. Critical associated information, including ...
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How Does Altis Biosystems Envision the Future of the Pharma/Biopharma Industry?
There is a growing need to address the high failure rate of drug candidates as they progress through clinical trials. Altis Biosystems aims to bring its technological advances to the forefront, enabling the drug development process to more effectively translate results from preclinical experiments to late-stage clinical trials. Breaking the Conformity of Inadequate Testing Platforms The ...
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Key Takeaways from BIO 2022 for AI-enabled Drug Discovery
It was great to be back in person at the 2022 BIO International Convention this year. It came as no surprise to us at Recursion that artificial intelligence (AI) and machine learning (ML) were hot topics at the conference, with more than half a dozen sessions exploring how these technologies are driving digital transformation in biopharma. We heard from leaders who are applying AI at ...
By Recursion
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The Power Of RepliGut in Vitro Intestinal Stem Cell Models
Both current in vitro and in vivo models used in the development of candidate therapies for the treatment of intestinal diseases have severe limitations. RepliGut®, an in vitro human intestinal epithelial stem cell model, addresses many of these issues and has significant potential to reduce the time and cost of drug development. This model may even help to identify optimal therapies for ...
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Sample Management Best Practices
With Genemod's industry-leading freezer management software, you can now set up proactive alerts to help you stay on top of inventory and place orders to replenish your supplies. Optimizing your sample management will increase your productivity and save time and money. Read on to find out about best practices. What is Sample Management? Sample management refers to an individual laboratory ...
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Recapitulating the Multifaceted Inflammatory Environment of the Intestine In Vitro
Intestinal inflammatory diseases are highly complex, which has thus far prevented development of an effective in vitro disease model. With access to a donor-derived cell biobank and the ability to recapitulate region-specific environments of the intestine, Altis Biosystems is working toward the development of an in vitro RepliGut® model to accurately recapitulate the complex intestinal ...
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Enhancing Human Gut Tissue Models through Gene Editing
The variety of normal and diseased human tissues needed to perform comprehensive screening of drug candidates is a key resource for next-generation preclinical models, but obtaining these tissues is challenging. Gene editing enables Altis Biosystems to offer a diverse array of RepliGut® human gut models tailored for specific research programs. Many Challenges Around Accessing Tissues ...
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Back to blog Federated Architecture in Genomics
Genome initiatives spearheaded by burgeoning numbers of data custodians such as Genomics England (GEL), a Lifebit customer, leverage technological advances to amass large volumes of patient data. As a result, data custodians are veritable gold mines of genome data that could transform precision medicine and provide an equitable solution for diverse healthcare requirements. Pharmaceutical ...
By Lifebit
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Delivering a precision medicine programme at scale
The Covid-19 pandemic highlighted the disparity between those who succumbed to severe illness while others remained relatively unaffected, underscoring the urgent need to shift the healthcare industry’s focus from a one-size-fits-all approach to more personalised healthcare. Personalised medicine promises to transform healthcare with treatments tailored to a patient’s unique genetic ...
By Lifebit
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Evaluating Microbiome Therapies with Intestinal Cell Models
The microbiome has been shown to play roles in many different disease processes and is implicated in many more, from infectious and gastrointestinal diseases to autoimmune and neurological disorders. Advanced models of the gut leveraging intestinal and colonic stem cells are enabling the development of more reliable and robust systems for evaluating the impact of changes in the microbiome on gut ...
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