Bioinformatics Data Analysis Articles & Analysis
33 articles found
This article outlines best practices for the bioinformatics analysis of 16S rRNA sequencing, emphasizing the critical stages of data preprocessing and quantification. Bioinformatics Pipeline Overview The bioinformatics pipeline for 16S rRNA sequencing can be broadly divided into two main stages: ...
The detailed point is to sequence the unknown genome sequence, and use bioinformatics analysis means to splice and assemble the sequence, so as to obtain the map of its genome. ...
Meanwhile, it's a useful tool for studying disease occurrence and progression, pharmacological action, bio-developmental molecular mechanisms, and more. Workflow and Bioinformatic Analysis Pipelines of RNC-mRNA Sequencing There are four major steps in the RNC-mRNA sequencing workflow: (1) sample preparation, (2) library preparation, (3) sequencing, and (4) ...
Navigating the Path from Wet Lab to Dry Lab The high-throughput sequencing of pathogens necessitates a two-fold process: wet lab experimentation and subsequent bioinformatics analysis. Wet lab endeavors encompass sample pretreatment, nucleic acid extraction, library construction, and ultimately, sequencing. Meanwhile, dry lab bioinformatics ...
Collagen, as one of the most abundant proteins in the human body, plays a key role in maintaining the integrity and function of tissue structures. With the development of bioengineering technology, recombinant human collagen (rhCollagen) produced by recombinant DNA technology has been widely applied in various fields such as medicine, cosmetics, and tissue engineering. Therefore, qualitative ...
The company is based on Thermo Fisher's Q ExactiveHF mass spectrometer, Orbitrap Fusion mass spectrometer, Orbitrap Fusion Lumos mass spectrometer combined with Nano-LC and rich biological analysis experience, and has established a new generation of protein, peptide, and antibody sequencing platforms. You only need to tell us the purpose of the experiment and send the samples, ...
Antibodies are an essential part of our immune system, capable of recognizing foreign molecules (antigens) and helping to eliminate them. Antibodies have a high degree of target specificity, affinity, and safety, and have been widely used in the treatment, diagnosis, and prevention of many major diseases. They are currently a focus in new drug development. The design of antibody drugs is a ...
Structural Variant Analysis: SVs, or variations in the structure of an organism's chromosome, are studied. ...
As the technology matures, so does the bioinformatics analysis of ONT data. Researchers have been diligently developing specialized tools and algorithms to better utilize the unique characteristics of ONT data, such as long read lengths and ionic current signals. ...
Methods for detecting RNA modifications Currently, most methods used to detect RNA modifications fall into three categories: high-throughput whole-transcriptome sequencing technologies, mass spectrometry methods, and bioinformatics analysis. While the advent of next-generation sequencing provides a wealth of sequence information in a single run, it requires ...
Small RNA sequencing, an example of targeted sequencing, is a powerful method for small RNA species profiling and functional genomic analysis. Here, we present the guidelines for bioinformatics analysis of small RNA sequencing. ...
The TCR-Seq service provides several advantages： First, CD Genomics efficiently extracts DNA or RNA and uses the Illumina platform for high-throughput sequencing, ensuring the quality and reliability of the data. Second, CD Genomics utilizes multiple bioinformatics tools, including VDJtools and tcR, to accurately genotype TCR sequences and identify clones. ...
But faced with the enormous amount of sequence data, how do we best deal with it? And what are the most appropriate computational methods and analysis tools for this purpose? ...
Project Summary 1. Project Design Throughout the project, INCOGEN collaborated closely with a team of professionals from the College of William & Mary (W&M) and other institutions to develop an effective plan for assessment and design of the educational software and its introduction into the classroom. This team was comprised of bioinformatics educators from the Departments of Biology, ...
Unlike amplicon sequencing, metagenomics obtains and investigates genetic material directly from environmental samples, which has led to a new understanding of the diversity and function of the microbial world. Bioinformatics analysis is one of the most important procedures for this purpose. ...
· Reproductive tract The microorganisms in reproductive tract are important for women's health, reproductive function and infant's birth. 16S/18S/ITS amplicon sequencing can obtain the information of most microorganisms in the genital tract. Through bioinformatics/statistical analysis, a large number of data are processed and ...
The qualified library will be sequenced (mainly using Illumina sequencing platform). The raw data obtained by sequencing will be used for bioinformatics analysis. ...
Sequencing the entire microbial genome is important for construction of accurate reference genomes, microbial identification, and other comparative genomic studies. Comparative genomic analysis based on whole genome sequencing plays an irreplaceable role in studying pathogenic mechanisms of pathogenic microorganism, evolution of pathogenic genes and screening of novel, efficient ...
This article provides a brief introduction to good practices for the bioinformatics analysis of 16S rRNA sequencing by NGS (next-generation sequencing). The bioinformatics pipeline involves two main stages: the preprocessing of data (quality control) and quantification (including taxonomic profiling and predictive metagenomics ...
Unlike amplicon sequencing, metagenomics obtains and investigates genetic material directly from environmental samples, which has led to a new understanding of the diversity and function of the microbial world. Bioinformatics analysis is one of the most important procedures for this purpose. Bioinformatics pipeline for viral metagenomics The ...