biologic matrix Articles
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Analysis of Opioids Using Isotope Dilution with GCMS-TQ8030 GC/MS/MS
Development of methods for analysis of drugs of abuse has become a high priority for both forensic toxicology and law enforcement. The large numbers of individual drugs and new "designer drugs" has made method development for these compounds a significant undertaking. Gas chromatography mass spectrometry (GCMS) has been used extensively for analysis of drug residues and trace-level drugs in ...
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Improved 3D Liver Model Could Forever Change Drug Testing – Allevi Author
The liver plays an incredibly important role in the human body by metabolizing drugs and other compounds. Developing accurate in vitro liver models to study is a critical step in better understanding the biological dynamics of our bodies and removing our dependence on animal models. In their recent publication, Allevi authors Marie Cuvellier, Frédéric Ezan, Hugo Oliveira, Sophie ...
By Allevi, Inc.
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7 Advantages of NovoSorb BTM
Complex wounds often involve exposed deep structures of the dermal layer, requiring prompt wound closure and tissue reconstruction. It is essential to quickly assess the defect and identify the most effective treatment method for optimizing the patient’s experience and outcome. Often, dermal substitutes are selected as a surgical option for temporizing the wound bed while also facilitating ...
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Silica-based nanoporous sol-gel glasses: from bioencapsulation to protein folding studies
Organic-inorganic nanoporous silica sol-gel glasses constitute the ideal support for protein bio-encapsulation and to study the different factors influencing the protein folding process in a crowded environment. Due to the facile silica surface modifications with desired Si-substituted organic groups from organosilanes precursors, organically modified 'wet-aged' silica-based glasses obtained via ...
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Essential Facts about NovoSorb BTM
When trauma to the skin occurs, large areas of both the skin’s surface (epidermis) and deeper layers (dermis) may be destroyed. In many cases, large full-thickness wounds may require temporization due to the lack of suitable donor sites for primary skin grafting. Clinical research[1] indicates the temporization of deep, large wounds with dermal scaffolds can not only help provide ...
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Top-Down Proteomics vs. Bottom-Up Proteomics
Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins. Edman degradation of peptide is a revolutionary method to identify the main amino acid sequence of peptide. In addition, the whole sequence of proteins can be determined by ...
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Top-Down Proteomics vs. Bottom-Up Proteomics
Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins. The Edman degradation of peptides is a revolutionary method to identify the main amino acid sequence of a peptide. In addition, the whole sequence of proteins can be determined by ...
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