Biological Research Articles & Analysis: Older
52 articles found
Knockin cell line generation represents a pivotal advancement in genetic engineering, providing vital tools for biological research and therapeutic development. This process involves the integration of specific DNA sequences into precise loci within the genome, allowing scientists to explore gene function, model diseases, and develop new treatments. ...
These units can represent various biological classifications, including individuals, species, genera, or even higher taxonomic levels. ...
This article delves into the characteristics, applications, and significance of the HCEC-12 cell line in biological and medical research. Origin and Characteristics Derived from the limbal region of the cornea, HCEC-12 cells retain many properties of native corneal epithelial cells. ...
Technological advancements and innovative research have continuously led to the discovery and development of new methodologies in the field of biological and medical sciences. ...
Sialic acid proteins are a special type of glycoproteins, characterized by the presence of sialic acid at the end of the sugar chain. Sialic acid is a biologically important sugar molecule that plays a crucial role in many intercellular interactions, including cell recognition, adhesion and signal transduction. Therefore, the detection of sialic acid proteins holds significant ...
Here are some specific examples to illustrate the selection of the number of parallel samples in different situations.Basic Biological ResearchIn basic epigenomics research, such as studying how the methylation status of a gene affects gene expression, at least three parallel samples are usually needed. This can help researchers distinguish ...
Immortalized cell lines are valuable tools in biological research and drug discovery, as they provide a continuous and stable cell population for experimental studies. The ability to immortalize cells that were previously resistant to traditional methods opens up new avenues for studying complex biological processes, disease mechanisms, and ...
Furthermore, to facilitate centrosomal research, CD BioSciences has long been probing centrosomes as a target for cancer therapy. ...
In-depth research on protein interaction plays a crucial role in life science research. Proteins are the main bearers of life activities, and their interactions form a complex molecular network within biological cells. Protein-Protein Interaction Sequencing (PPI-Seq) is an emerging technology. ...
Overview of Single-Antibody SequencingSingle-antibody sequencing, as the name suggests, is a technique that uses a single antibody to sequence DNA. This method is based on the specificity of the antibody, which recognizes and binds to specific DNA sequences to accurately read the DNA.Working Principle of Single-Antibody SequencingThe basic principle of single-antibody sequencing is: select a ...
This predictive modeling approach allows researchers to systematically design and optimize biomaterials with specific mechanical, biological, and chemical properties. ...
Using advanced algorithms and machine learning techniques, researchers can explore vast chemical spaces to identify promising lead compounds, which can then be further refined and validated through experimental testing. ...
Technological advancements and innovative research have continuously led to the discovery and development of new methodologies in the field of biological and medical sciences. ...
Due to the ease of formulation, self-assembly, and high load-carrying capacity of liposomes, researchers combined SM-PROTAC with liposomes, leading to the development of a split-and-mix nanoself-regulating platform called LipoSM-PROTAC. This platform was characterized and validated for its biological performance. Initially, researchers modified ...
These cutting-edge substrates offer superior signal sensitivity, long-term storage stability, enhanced safety, and user-friendliness, empowering researchers to unlock deeper insights into protein expression and function within tissues. ...
Biofabrication: Bio-ink can be used to create complex biological structures for research and development, such as microfluidic devices for drug delivery. ...
ByMatexcel
In the realm of biological sciences, bile acids stand as pivotal molecules, playing a multifaceted role in various physiological processes within organisms. ...
It has been considered that diseases are generally influenced by obtained biological alterations, but it is becoming evident that any phenotype is the result of a complex interplay between genotype, epigenome, and environment. ...
In the ever-evolving realm of biotechnology, the astonishing advancements in mRNA (messenger RNAs) synthesis are poised to revolutionize various aspects of biological research. This article delineates the eclectic vistas opened up by custom mRNA synthesis services that provide bespoke, high-quality solutions for researchers globally. ...
The phenomenal advancements in the realm of biotechnology have propelled the development of tools with remarkable potential, considerably altering the landscape of biological and medical research. One such groundbreaking tool topping the list among modern biotechnologies is the Single Guide RNA (sgRNA) library. ...