biomaterial implant Articles
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Molecular interactions of degradable and non-degradable polymers with hydroxyapatite influence mechanics of polymer-hydroxyapatite nanocomposite biomaterials
Implant materials composed of hard and soft phases (composite materials) have shown much promise for total bone replacement. Interfacial interactions between the components in these composite biomaterials affect the overall mechanical response. Here, the role of interfacial interactions on the load deformation behaviour of soft phase (polymer) have been analysed using constant velocity Steered ...
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The effect of mixing technique on fatigue of bone cement when stress concentrations are present
Mixing techniques used to reduce porosity in bone cement demonstrate large improvements in fatigue behaviour in test specimens, but do not appear to reduce the rate of loosening of implants in vivo. We examined data showing the effect of notches on fatigue strength and found, surprisingly, that notches with low stress-concentration factors (Kt Keywords: mixing technique, fatigue strength, bone ...
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Evonik Enhances Glycolide-Based Polymer Portfolio for Medical-Textile Materials
Evonik has announced the signing of an exclusive global agreement with ITV Denkendorf Produktservice (ITVP), a German-based R&D and manufacturing leader for medical-textile materials. New Platform of Glycolide-based Polymers Under the agreement, Evonik will expand its market-leading RESOMER® portfolio with the launch of a new platform of glycolide-based polymers suitable to produce ...
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A nitric oxide releasing, self assembled peptide amphiphile matrix that mimics native endothelium for coating implantable cardiovascular devices
Abstract Cardiovascular disease is the number one cause of death in the United States. Deployment of stents and vascular grafts has been a major therapeutic method for treatment. However, restenosis, incomplete endothelialization, and thrombosis hamper the long term clinical success. As a solution to meet these current challenges, we have developed a native endothelial ECM mimicking ...
By Endomimetics
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Diamond coated microtools for machining compact bone
The structure of compact bone is heterogeneous and as such, is difficult to shape by cutting tools during clinical surgical practices. The structure of bone can have a devastating effect on the performance of the cutting tool unless it is coated with a thin solid film that is wear resistant. The paper investigates the use of diamond coated cutting tools to prepare bone for prosthetic implants and ...
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Ultrastructural characterisation of the hydroxyapatite–coated pedicle screw and human bone interface
The early fixation of pedicle screws is crucial for improving spinal stabilisation. Firm and immediate fixation between pedicle screws and bone prevents aseptic loosening and implant failure. Coating with hydroxyapatite is a possible method to improve the fixation of metallic implants in bone. In this study, scanning transmission electron microscopy (STEM) has been used to investigate the ...
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