biomedical development Articles
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The race for pace: inhibitors and accelerators – developing the first product in new science-based companies
Previous literature on product development in the field of biotechnology has not focused on how a product is moved from step to step. Thus, insight into issues of crises and managerial choices in the process has not been provided. This paper gets down to the bench-level of bio-entrepreneurship by studying the challenges involved in developing the first product in a company. Through case studies ...
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Calviri’s Stephen Johnston discusses job opportunities for students
As Phoenix’s bioscience initiative grows, so do job opportunities for students By the end of the year, over $3 billion will have been invested into Phoenix’s bioscience and healthcare facilities, creating more than 8,000 jobs Phoenix City Council voted to fund the Bioscience Healthcare Strategic Initiative for the 2021-2022 fiscal year last Tuesday, a plan set to help create new job ...
By Calviri
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The Crucial Role of Cytokines in Biomedical Research and Drug Development
Low Endotoxin Cytokines Matters Organoid culture, CAR-T cell therapy, stem cell therapy, and other topics have become broadly discussed among biomedical researchers. In fact, it is not difficult to see that these advanced technologies are all related to cell culture. In order to maintain efficient growth, proliferation, and differentiation during in vitro cell culture, many cell cultures require ...
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Nanotechnology in biomedical applications: a review
Incorporation of functionalised and modified nanostructures in various biomedical applications has generated considerable research interest in recent years. The applications of nanotechnology in medicine and biomedical engineering are vast and spans areas such as implant and tissue engineering, diagnosis and therapy. The present scenario demands designing of nanotools which can respond to the ...
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Bioartificial liver: review of science requirements and technology
Social development in health services is concerned as a global issue. More than nine million people die due to internal organ failure and one percent of this number is due to liver disease. In 1990, more than 27,000 deaths in the USA were caused by liver failure. From the numerous reviews on liver failure and associated support therapies, there is increasing interest in this field throughout the ...
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Using Go!SCAN 3D Scanner for the Individualized Orthopetic Development in Medical Technology
The laboratory for additive manufacturing (LaF) at Landshut University, deals with the process of reverse engineering headed by Prof. Dr.-Ing. Norbert Babel. This includes scanning objects, scanning data processing using special software tools and transfer to a CAD system, modeling and simulating, as well as generating prototypes developed which are manufactured with different additive ...
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Micron developing microneedle technology for self-administration of vaccines and therapeutics
Closely-held Micron Biomedical is developing a dissolvable microneedle-based technology that could enable self-administration of vaccines and therapeutics. “While microneedle technology is not new, our company represents the evolution of the technology over many years,” Steven Damon, CEO, says in an interview with BioTuesdays.com. “We’re developing an innovative ...
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The Emergence of a New Force: Circular RNA
Circular RNAs are closed-loop single-stranded RNA (ssRNA) that are structurally specific, and produced by the back-splicing process. CircRNAs can exist independently of proteins and are unaffected by exonucleases, and are widely found in plant and animal cells to regulate gene expression. Circular RNAs were first discovered by Sanger studying virus-like RNAs. And in 1991, Nigro stumbled upon an ...
By CD Genomics
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The Liposome-Based PROTAC Strategy
Proteolysis Targeting Chimeras (PROTACs) are a novel approach for degrading target proteins. Recently, a new split-and-mix PROTAC (SM-PROTAC) system based on liposome self-assembly, known as LipoSM-PROTAC, was reported in the Journal of the American Chemical Society. The LipoSM-PROTAC system exhibits selective degradation of target proteins, with folate serving as a key ligand. In this study, the ...
By BOC Sciences
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Bioprocess Automation, Remote Monitoring, and Real-Time Data Capture Underpin Operation Warp Speed’s Push for a COVID-19 Vaccine
Life science companies spanning the globe are striving to quickly develop and commercialize COVID-19 therapeutics and grab the brass ring of a viable, effective, and safe SARS-CoV-2 vaccine. In the United States, pharmaceutical and biotech companies, as well as Contract Development and Manufacturing Organizations (CDMOs), from coast-to-coast are racing to complete clinical trials and forge ...
By Lab Owl
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Developing a Robust in Vitro Intestinal Model for Preclinical Candidate Screening of GI Toxicity
Gastrointestinal (GI) issues are common side effects of many drugs. Anticipating such side effects before clinical trials is limited by a lack of effective models for evaluating preclinical candidates for their potential to cause diarrhea, nausea, and other gut-related side effects. With its RepliGut® in vitro human intestinal model, Altis Biosystems is developing a system that could help ...
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Discovery of Bispecific Antibodies and Immune Checkpoint Inhibitors That Kill Glioblastoma Cells and Melanoma Cells, and Block the Metastasis of Malignant Melanoma Cells to the Lung by Over 90%
Ocean Biomedical will be a wholly owned subsidiary of Aesther Healthcare Acquisition Corp. and will change its name to Ocean Biomedical, Inc., expected to be listed on NASDAQ under the symbol, “OCEA”. PROVIDENCE, R.I. and NEW YORK, Sept. 06, 2022 (GLOBE NEWSWIRE) -- Ocean Biomedical and Aesther Healthcare Acquisition Corp. (“Aesther”) (NASDAQ: AEHA) ...
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Module 3: Culture Medium
This is the third module in a four part series titled “Zero to One on the basic science behind cultivated meat”. You can click on these links to access: Course Overview, Module 1 (Cell Culture Basics), Module 2 (Cell Sources), Module 4 (Process monitoring). Learning objectives By the end of this module, you should understand: Basal culture medium composition and sources; ...
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