Biomedical Science Articles & Analysis
73 articles found
Optogenetics has emerged as a transformative tool in the field of neuroscience, allowing researchers to manipulate neuronal activity with unprecedented precision. At the heart of this technology lies the use of adeno-associated viruses (AAVs), which serve as robust delivery vehicles for light-sensitive proteins into targeted neuronal populations. This article delves into the significance of ...
In recent years, the field of gene editing has experienced groundbreaking advancements, with CRISPR/Cas9 emerging as a powerful technology for precise genetic manipulation. Among various delivery systems, lentiviruses have garnered significant attention due to their ability to introduce genetic material into both dividing and non-dividing cells, making them an ideal vehicle for gene therapy ...
Histological image analysis has emerged as a pivotal domain in biomedical research and clinical diagnostics, allowing scientists and healthcare professionals to decipher the intricate structures of tissues at a microscopic level. This analysis encompasses the examination of biological tissues to understand their composition, organization, and pathology, which can be crucial for diagnosing ...
Research in the field of pulmonary biology often requires detailed analysis of lung tissues. One of the optimal methods for studying lung structures and functions in mice is the use of C57 mouse models, specifically through the preparation of frozen sections. This technique is vital for a variety of applications, including histological studies, immunohistochemistry, and molecular analysis. Why ...
Cytokines are small proteins that play a crucial role in cell signaling, particularly in the immune system. They regulate inflammation, immunity, and hematopoiesis, making them essential for understanding various biological processes and disease mechanisms. For researchers working with rabbit models, the ability to accurately measure cytokine levels is vital. This is where Customized Rabbit ...
In the realm of biomedical research, the study of cytokines and chemokines plays a pivotal role in understanding the immune system and its responses to various stimuli. For researchers working with rat models, the Rat Cytokine and Chemokine Panel offers an invaluable set of tools to investigate these complex signaling molecules. In this article, we will explore what cytokines and chemokines are, ...
Watertown, MA – March 24, 2025 – Biopharma PEG, a leading supplier of high-quality polyethylene glycol (PEG) derivatives, highlights its innovative product DSPE-PEG-Mannose, an advanced biomedical polymer with significant potential in drug delivery, tumor-targeted therapy, tissue recognition, and adhesion.Structural Advantages of DSPE-PEG-MannoseDSPE-PEG-Mannose is composed of three key ...
The advent of organoid technology has transformed biomedical research through the development of 3D models that precisely replicate human organ structures and functions in a physiological context. Creative Bioarray establishes itself as a world leader in life science innovation through its complete range of organoid services that enhance drug discovery, disease ...
Simple Summary The present study investigated possible administration of pectin derived from apple pomace as a beneficial and cost-effective feed additive to be used in trout culture. To achieve the aim, a range of parameters were measured including immune parameters (both at physiological and molecular levels), growth performance and digestive enzyme activity. The results showed promising ...
The quest for effective therapeutics begins long before a drug reaches clinical trials. One of the cornerstones of this process is drug screening in animal models, which plays a pivotal role in evaluating the safety and efficacy of potential treatments. Animal models offer researchers valuable insights that cannot be obtained through in vitro studies alone, bridging the gap between laboratory ...
Disease Research: By mapping altered flux patterns in cancer cells, cardiovascular diseases, or diabetes, MFA helps identify potential metabolic vulnerabilities or biomarkers for diagnosis and therapy. Agricultural Sciences: MFA can uncover mechanisms by which plants adapt to environmental stresses, aiding in crop improvement. ...
Understanding the immune system is fundamental to advancing biomedical research, especially in areas such as cancer, autoimmune diseases, and infectious diseases. Mouse models play a pivotal role in this field, as their immune system shares many similarities with that of humans. A key aspect of studying the immune system involves analyzing cytokines, chemokines, and growth ...
This article delves into the Luminex platform, its application in multiplex cytokine analysis, and the relevance of growth factor assays in biomedical research. What Is a Luminex Cytokine Panel? The Luminex xMAP technology is an advanced bead-based multiplex assay platform that leverages the power of color-coded microspheres to perform high-throughput, simultaneous detection of ...
Stable cell lines are an indispensable tool in the realm of biomedical research, playing a crucial role in advancing our understanding of cellular processes and disease mechanisms. Unlike primary cells that have a limited lifespan, stable cell lines offer a consistent and renewable source of cells, making them invaluable for long-term studies and industrial applications. This article explores the ...
Gene editing has emerged as a transformative tool in the field of biomedical science, with significant implications for the treatment of various diseases. ...
HCEC-12 is a well-established human corneal epithelial cell line derived from human corneal tissue. It plays a crucial role in ocular research, particularly for studies related to corneal physiology, wound healing, and the pathogenesis of various ocular diseases. This article delves into the characteristics, applications, and significance of the HCEC-12 cell line in biological and medical ...
Collagen is an important structural protein that is widely found in various biological tissues, such as skin, bones, tendons, and blood vessels. Accurate determination of collagen content is very important for biomedical research, disease diagnosis and quality control of related products. Here are some commonly used methods for determining collagen content.ChromatographyHigh-performance liquid ...
Sialic acid proteins are a special type of glycoproteins, characterized by the presence of sialic acid at the end of the sugar chain. Sialic acid is a biologically important sugar molecule that plays a crucial role in many intercellular interactions, including cell recognition, adhesion and signal transduction. Therefore, the detection of sialic acid proteins holds significant value in disease ...
In biomedical research, the detection and analysis of biomarkers are crucial. Among them, glycoproteins are an essential biomarker that plays a key role in many biological processes, including disease onset, progression, and treatment response. The Tandem Affinity Purification (TAP) of glycoprotein is an efficient detection method.What Is a Glycoprotein?Firstly, let's understand what a ...
Boxcab Antibody Sequencing is an important experimental method commonly used in studying cellular and protein responses. In biomedical research, antibodies are a powerful tool used in the detection and quantification of target antigens. However, a comprehensive understanding of the antibody requires knowledge of its amino acid sequence, which can be achieved through antibody sequencing.Antibody ...