bioprinter Articles
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Fabrication And Characterization Of 3D Bioprinted Triple-Layered Human Alveolar Lung Models
Researchers from Nanyang Technological University and its Center for 3D printing (SC3DP) have developed a 3D printed a highly repeatable and scalable three-dimensional in-vitro alveolar lung model using our REGENHU bioprinter, that could be exploited for pathogen translocation studies and respiratory-related toxicological testing applications. The triple-cell layered lung model was realized ...
By Regenhu
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Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening
Publication Summary: Recent advances in the directed differentiation of human pluripotent stem cells to kidney organoids advances the prospect of drug screening, disease modelling, and even restoration of renal function using patient-derived stem cell lines. Here, we demonstrate the successful adaptation of our directed differentiation protocol to the NovoGen Bioprinter® MMX technology to ...
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Fabrication Of In-Vitro Phenotypically Stable Engineered Articular Cartilage
Researchers from IRCCS Istituto Ortopedico Rizzoli and Indian Institute of Technology, Delhi (IIT) used their REGENHU bioprinters to fabricate an in vitro phenotypically stable engineered articular cartilage by embedding human bone marrow-derived stromal cells (hMSCs) in a cell-laden silk fibroin–gelatin (SF-G) bioink. The bioprinted constructs allowed the in vitro study of chondrogenic ...
By Regenhu
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3D-printed blood vessels in monkeys marks medical breakthrough towards artificial organs
A Chinese firm has made a major medical breakthrough by succeeding in developing 3D-printed blood vessels that have been successfully implanted into monkeys, which is a major step towards making artificial human organs possible in future. Sichuan Revotek is a Chinese biotechnology firm that developed a 3D bioprinter back in 2015 which prints using stem cell-based bio ink, and it has now ...
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BeadReady™ successfully storing cells for 3D biofabrication
Another fantastic publication highlighting one of the multiple applications Atelerix products have within the scientific research and development industry. Anastassia Kostenko , Che J. Connon, and Stephen Swioklo (2023), have successfully shown that Atelerix BeadReady™ is a simple, adaptable solution for room temperature cell storage in combination with biofabrication and how this can be ...
By Atelerix Ltd
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3D Bioprinting Of Prevascularised Implants For The Repair Of Critically-Sized Bone Defects
By combining different cell populations in a fibrin bioink, researchers from Trinity College Dublin, Royal College of Surgeons in Ireland and University of Illinois Chicago were able to sprout an in vitro microvessel network that was then exploited to prevascularise a 3D printed scaffold implanted in a critical size femoral defect using REGENHU bioprinter. This dual approach was observed to ...
By Regenhu
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Bioprinting Algae To Improve Tissue Oxygenation
Engineers often rely on Mother Nature to help solve difficult problems. After millions of years of evolution, living organisms such as plants, animals, and microbes have discovered how to survive in even the harshest of environments. Often times, organisms from different species are able to provide each other with the nutrients, resources, or protection that both need to prosper. We call ...
By Allevi, Inc.
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Bio-Ink: Printing the Future of Medicine and Beyond
Bio-ink is a revolutionary material that is rapidly changing the fields of medicine, tissue engineering, and even bioprinting food. This fascinating substance is essentially a type of ink made from living cells and other biocompatible materials that can be used to 3D print complex biological structures. What is Bio-Ink Made Of? The composition of bio-ink can vary depending on the desired ...
By Matexcel
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Cells isolated from donors with nonalcoholic fatty liver disease exhibit disease phenotypes in 3D bioprinted human liver tissue
Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) bioprinted liver tissue. The characteristics of donors from which the ...
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LLNL Uses 3D Bioprinting to Produce Live Cells
On March 5, 2019, the Lawrence Livermore National Laboratory (LLNL) announced that their researchers have 3D printed live cells that are able to convert glucose to ethanol and carbon dioxide gas. The substance produced from this conversion resembles beer. This means that this newly developed technology can lead to highly efficient biocatalysis. According to LLNL’s announcement, the use ...
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Long-term performance of implanted bioprinted human liver tissue in a mouse model of human alpha-1 antitrypsin deficiency
Publication Summary: Conventional cell therapy and tissue engineering approaches to treating liver diseases and injury are limited by low cell retention, poor engraftment, poor graft durability and complications including portal hypertension. Integration of next generation technologies such as 3D bioprinting is an essential step towards the clinical success of these promising approaches and has ...
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Improved 3D Liver Model Could Forever Change Drug Testing – Allevi Author
The liver plays an incredibly important role in the human body by metabolizing drugs and other compounds. Developing accurate in vitro liver models to study is a critical step in better understanding the biological dynamics of our bodies and removing our dependence on animal models. In their recent publication, Allevi authors Marie Cuvellier, Frédéric Ezan, Hugo Oliveira, Sophie ...
By Allevi, Inc.
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SPACE BIO-3D PRINTING FROM HUMAN CARTILAGE TO THYROID GLAND IN RODENTS AND TO SPACE ARTIFICIAL MEAT
Space bio-3D printing from Human Cartilage to Thyroid Gland in Rodents and to Space Artificial Meat: SUNKYE Satisfies the Connection and Signal System of Bio-3D Printing in Micro-gravity Environment Space bio-3D printing may be a concept we've heard recently. But as with 3D printing technology, there was only a short accumulation before it happened! Do we need Space bio-3D printing? Can't we ...
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Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis
Publication Summary: Compound induced chronic liver injury can lead to initiation of profibrotic processes resulting in sustained production of growth factors and profibrotic cytokines where inflammation, tissue remodeling and repair pathways are activated simultaneously to counteract the injury. Evaluation of potential antifibrotic therapies are limited using conventional non-human animal ...
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Modeling NAFLD using 3D bioprinted human liver tissue
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease, with a prevalence of 25% ...
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Andy Slavitt: When it comes to AI, it is the best of times, worst of times story
AI is a topic that fuels the passions of healthcare entrepreneurs but is it also a distraction from where the real pain points in healthcare are? A panel discussion on AI at the J.P. Morgan Healthcare Conference wrestled with the issue. Artificial intelligence is the kind of topic that brings out the inner geek in all of us. There is so much excitement about its potential applications and where ...
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Modeling NAFLD using 3D bioprinted human liver tissue
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease in the western world, with an ...
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Bioinspired Hydrogel To Improve The 3d Printability Of Mechanically Demanding Tissues Such As Intervertebral Disc
Researchers from Albert-Ludwigs-Universität Freiburg im Breisgau, Université Claude Bernard Lyon 1, Universidad Central “Marta Abreu” de Las Villas and Johannes Gutenberg-Universität Mainz developed a 3d printable, bioinspired hydrogel composed of two different biopolymers, chitosan and cellulose nanofibers, through an environmentally friendly process by avoiding both ...
By Regenhu
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A human in vitro three-dimensional bioprinted liver tissue system can be used to model nutritional damage and protective effects of MSDC-0602K, a novel modulator of the mitochondrial pyruvate carrier (MPC)
Publication Summary: The growing global incidence of NASH mirrors the availability of nutrients. Over-nutrition also results in insulin resistance and type-2 diabetes, which are often co-morbidities associated with NASH and are known to drive more adverse outcomes. MSDC-0602K, a modulator of the mitochondrial pyruvate carrier (MPC), is in clinical trials as a potential treatment for NASH. ...
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Cultured Protein: A Guide to Every Cell-Based Meat Startup in the World Right Now
The alternative protein market is on fire right now, estimated to be worth approximately $2.2Bn, and cultivated meat is expected to play an important role in the shift from traditional meat products. Experienced scientists are engaged in cellular agriculture with the aim of reducing animal-based agriculture’s negative impact on both the planet and the suffering of animals and at the same ...
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