biopsy Articles
-
Evaluation of an Epigenetic Assay for Predicting Repeat Prostate Biopsy Outcome in African American Men
Abstract Objective: To evaluate an epigenetic assay performed on tissue from negative prostate biopsies in a group of African American (AA) men undergoing repeat biopsy, and to compare accuracy for predicting repeat biopsy outcome to prior studies conducted in predominantly Caucasian populations. Materials and methods: The study population consisted of 211 AA men from 7 urology centers ...
By MDxHealth
-
Clinical Case Study: Invasive Ductal Carcinoma (IDC) and Ductal Carcinoma In Situ (DCIS)
Description: Description: 71-year old female presented for a routine screening mammogram Protocol: PROTOCOL: 1. August 2007 left breast mammogram showed large area of abnormality lateral aspect of breast. Mammogram RT Breast CC Mammo RT Breast MLO Mammo 2. August 2007 left breast ultrasound showed mass at 1:00-3:00 ...
-
Decreasing Benign Breast Ultrasound Biopsies: Prospective Use of AI Decision Support
After implementation of AI decision support, the benign biopsy rate decreased from 71.79% to 59.2% while the overall biopsy rate stayed constant. PPV3 increased from 28.2% to 40.8%. Objective To examine the affect of prospective AI decision support (Koios DS Breast) use on breast ultrasound biopsy performance metrics. Materials and Methods Non-identifiable HIPAA compliant data collected ...
-
Human in vivo liver and tumor bioimpedance measured with biopsy needle
Congratulations to our research engineer Sanna for a new publication! Human in vivo liver and tumor bioimpedance measured with biopsy needle. 2022 Jan ...
By Injeq Oy
-
VLE for Identification of Subsquamous Disease - Case Study
Patient History This patient was a 68 year old man referred with short segment Barrett's Esophagus (BE) with intramucosal carcinoma (IMC). At the referring center, previous resection of nodularity revealed Tla adenocarcinoma with negative margins. Subsequent surveillance biopsies yielded IMC, and triggered referral. For the procedures described here, standard endoscopy with the addition of ...
-
An independent assessment of AI for prostate cancer detection - Case Study
Yale Medicine, an academic medical center with a high volume of prostate biopsies, conducted a study to determine Paige Prostate’s utility as a prescreening tool for clinical use. A total of 1,876 prostate core biopsy slides were analyzed by Paige Prostate, and only those cores categorized by the AI as “suspicious” or as out of distribution were manually reviewed by Yale ...
-
Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies
Abstract Background: Prostate cancer (PCa) diagnosis is challenging because efforts for effective, timely treatment of men with significant cancer typically result in over-diagnosis and repeat biopsies. The presence or absence of epigenetic aberrations, more specifically DNA-methylation of GSTP1, RASSF1, and APC in histopathologically negative prostate core biopsies has resulted in an ...
By MDxHealth
-
New trends in the management of late radiation morbidity
Currently, no reliable methods and no suitable marker profile exist that could predict radiosensitivity in patients. This paper describes the irradiation response of lymphocytes, fibroblasts and tumour biopsies cultured in vitro, clonogenic survival at 2 Gy (SF2), chromosomal aberrations, and CD4 and CD8 lymphocyte apoptosis. The results, and other accumulating evidence, strongly suggest that ...
-
Relative effectiveness of Frameless stereotactic biopsy
Brain biopsy procedure has been evolving for the last four decades in concurrence with the imaging developments of the brain. Frame-based stereotactic interventions are considered the conventional gold reference standard for obtaining biopsy specimens of lesions from the brain. In this modality, a bulky head frame is fixed to the patient’s head before imaging procedures as it is an integral ...
-
Spatially precise real-time bioimpedance from the tip of a biopsy needle can differentiate tissue types
Spatially precise real-time bioimpedance from the tip of a biopsy needle can differentiate tissue types. Annals of Biomedical Engineering, vol 47, num 3, pp. 836-851, 2019, doi: ...
By Injeq Oy
-
Inorganic elements in green sea turtles (Chelonia mydas): Relationships among external and internal tissues
Inorganic elements from anthropogenic sources have entered marine environments worldwide and are detectable in marine organisms, including sea turtles. Threatened and endangered classifications of sea turtles have heretofore made assessments of contaminant concentrations difficult due to regulatory restrictions on obtaining samples using non‐lethal techniques. In the present study, claw and ...
-
VLE for Post-Treatment Assessment - Case Study
Patient History This patient was originally referred with nodular esophageal disease that was endoscopically visible at the Castro-Esophageal Junction (CEJ). The area was treated using combination Cryotherapy and Endoscopic Mucosal Resection (EMRJ. (Figures 1-3) Pathology of the EMR sample was positive for Adenocarcinoma (Figure 4) A subsequent surveillance ECD showed the previous EMR site, a ...
-
Validation of ClarityDX Prostate as a Reflex Test to Refine Prediction of Clinically Significant Prostate Cancer: ClinicalTrials.gov ID: NCT03957252
Summary This study is designed to determine the accuracy of the blood test ClarityDX Prostate to predict the results of prostate biopsies in men who have PSA (Prostate Specific Antigen) greater than 3 and no higher than 10 ...
-
Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men.
Organizations Martini-Klinik Prostate Cancer Center and Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, MDxHealth, B.V., Nijmegen, Netherlands, MDxHealth, Inc., Irvine, CA, Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium, Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany Abstract ...
By MDxHealth
-
Freehand Transperineal Biopsy
“Freehand transperineal biopsy” seems to be the latest buzzword in the urology world, and for good reason. Compared to transrectal, transperineal is proven to be the cleaner and ultimately safer approach for prostate biopsies. The support for transperineal is growing, as mounting evidence continues to debunk previous misconceptions of tolerability, feasibility and accuracy. We ...
-
Micromate™ Case Report: Robot-Guided Bone Biopsy
Micromate™ Case Report series presents real cases performed by the physicians currently using our full-fledged robotic platform for percutaneous procedures. Today, we join Dr. Alexander Kupferthaler, Interventional Radiologist at the Ordensklinikum Linz – Barmherzige Schwestern, for a robot-guided bone biopsy. Clinical Context 65-year-old female with invasive lobular carcinoma of ...
-
Assessment of a urinary TRUS/biomarker-based risk score as inclusion criteria for multiparametric MRI to detect clinically significant prostate cancer
BACKGROUND Non-invasive techniques like urinary biomarkers and multiparametric Magnetic Resonance Imaging (mpMRI) show great promise for the detection of clinically significant prostate cancer (PCa), leading to a reduction of over-diagnosis and over-treatment. Apart from yet to be established diagnostic accuracy is the systematic use of mpMRI challenging due to the high cost of setting up, ...
By MDxHealth
-
Cost-Effectiveness of Urinary Biomarker Panel in Prostate Cancer Risk Assessment
Abstract Purpose: SelectMDx (MDxHealth®) is a panel of urinary biomarkers used in conjunction with traditional risk factors to individualize risk prediction for clinically significant prostate cancer. In this study we sought to characterize the effectiveness of SelectMDx in a population of American men with elevated prostate specific antigen. Materials and methods: We developed a ...
By MDxHealth
-
Raman ‘optical biopsy’ of human breast cancer
Abstract Raman imaging (RI) is a novel method of medical diagnostics of human breast cancer and has a potential to become a routine optical biopsy. Up to date the present study is the most statistically reliable Raman analysis based on data of normal, benign, and cancerous breast tissues for 146 patients. This paper present the first Raman ‘optical biopsy’ images of the normal and ...
-
Bio-tech firm recruiting Yukon men for trial, Prostate cancer group says it could save lives
The Yukon chapter of Ride For Dad says a new blood test developed by an Alberta-based company could save the lives of men at risk of prostate cancer. (iStock/Getty Images) A bio-technology company based in Alberta is testing a new process that could result in fewer Yukon men travelling out of territory for prostate cancer biopsies. Private research company Nanostics Inc. and the University of ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you