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Biopsy Sample Articles & Analysis

4 articles found

Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...

BySOPHiA Genetics


Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men.

Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men.

We evaluated SelectMDx clinical performance in a cohort of German men undergoing initial prostate biopsy.Methods:The study population consisted of 443 men sequentially enrolled men who underwent initial prostate biopsy between July 2009 and December 2014 due to suspected PCa. Post-DRE urine was collected from all subjects prior to biopsy, and ...

ByMDxHealth


The Power Of RepliGut in Vitro Intestinal Stem Cell Models

The Power Of RepliGut in Vitro Intestinal Stem Cell Models

For example, immune cells can be added either to the apical side, where they can intercalate into the monolayer, or to the basal side, where their cytokine secretions can interact with receptors on the basal side of the monolayer. We can also sample the cell culture supernatants to investigate epithelial responses; for example, by adding bacteria to the apical side of the ...

ByAltis Biosystems


Inorganic elements in green sea turtles (Chelonia mydas): Relationships among external and internal tissues

Inorganic elements in green sea turtles (Chelonia mydas): Relationships among external and internal tissues

Threatened and endangered classifications of sea turtles have heretofore made assessments of contaminant concentrations difficult due to regulatory restrictions on obtaining samples using non‐lethal techniques. In the present study, claw and skin biopsy samples were examined as potential indicators of internal tissue burdens in green sea turtles ...

ByJohn Wiley & Sons, Ltd.

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