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Biopsy Tissue And Blood Samples Articles & Analysis

4 articles found

Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...

BySOPHiA Genetics


Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men.

Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men.

Organizations Martini-Klinik Prostate Cancer Center and Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, MDxHealth, B.V., Nijmegen, Netherlands, MDxHealth, Inc., Irvine, CA, Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium, Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany Abstract ...

ByMDxHealth


The Power Of RepliGut in Vitro Intestinal Stem Cell Models

The Power Of RepliGut in Vitro Intestinal Stem Cell Models

Both current in vitro and in vivo models used in the development of candidate therapies for the treatment of intestinal diseases have severe limitations. RepliGut®, an in vitro human intestinal epithelial stem cell model, addresses many of these issues and has significant potential to reduce the time and cost of drug development. This model may even help to identify optimal therapies for ...

ByAltis Biosystems


Inorganic elements in green sea turtles (Chelonia mydas): Relationships among external and internal tissues

Inorganic elements in green sea turtles (Chelonia mydas): Relationships among external and internal tissues

Inorganic elements from anthropogenic sources have entered marine environments worldwide and are detectable in marine organisms, including sea turtles. Threatened and endangered classifications of sea turtles have heretofore made assessments of contaminant concentrations difficult due to regulatory restrictions on obtaining samples using non‐lethal techniques. In the present study, claw and ...

ByJohn Wiley & Sons, Ltd.

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