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Biosciences Articles & Analysis: This-Year
6 articles found
In the intricate world of cellular biology, proteins are the undisputed workhorses. They are assembled based on a genetic blueprint, but their story doesn't end there. After synthesis, proteins undergo a vast array of chemical modifications known as post-translational modifications (PTMs). These changes act as molecular switches, fine-tuning a protein's function, localization, and stability. ...
In recent years, the field of gene editing has experienced groundbreaking advancements, with CRISPR/Cas9 emerging as a powerful technology for precise genetic manipulation. Among various delivery systems, lentiviruses have garnered significant attention due to their ability to introduce genetic material into both dividing and non-dividing cells, making them an ideal vehicle for gene therapy ...
Fluorescence In Situ Hybridization (FISH) and Immunohistochemistry (IHC) are two powerful techniques widely used in biological and medical research. While each has its strengths, the combination of these methods—ImmunoFISH—offers a unique and comprehensive approach to investigation at the cellular and tissue levels. Understanding the Techniques FISH is primarily utilized for detecting ...
In the realm of biological research, the ability to accurately observe and analyze cellular components is paramount. Our experienced team specializes in providing advanced in situ hybridization (ISH) services, employing both bright field and fluorescent techniques to deliver precise insights into tissues and cells. The utilization of bright field microscopy allows for clear visualization of ...
Introduction Custom knockout cell lines represent a groundbreaking advancement in molecular biology and genetics, allowing researchers to manipulate genes with precision and study their functions in a controlled environment. By creating cell lines with specific genes “knocked out,” scientists can investigate disease mechanisms, screen drug candidates, and develop gene therapies more ...
Nicotinamide adenine dinucleotide (NAD) and its reduced form (NADH) are essential coenzymes involved in a wide array of cellular metabolic processes. As critical mediators in oxidation-reduction (redox) reactions, NAD/NADH plays a pivotal role in energy production and cellular metabolism. Understanding and analyzing these biomolecules has become increasingly important in areas such as disease ...