biotherapeutics Articles
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Needles and Pills: Rani Therapeutics Is Making Encapsulated Oral Biologics
Rani Therapeutics, a clinical-stage biotherapeutics company, based in San Jose, CA, is developing orally-administered biologics. Their novel, patented platform technology replaces subcutaneous or IV injection of biologics with oral dosing. The RaniPill capsule is an orally ingestible vehicle, approximately the size of a standard fish oil or calcium pill, which is designed to automatically ...
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The scientific basis for probiotic strains of lactobacillus
The concept of using Lactobacillus species for disease treatment and prevention as well as health restoration and maintenance is not new. However, in recent times, there has been a renewal of interest in the use of probiotics (as distinct from antibiotics) (also termed biotherapeutic agents), driven in large part by consumers and the lay press. Probiotics have been used therapeutically to ...
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3 Reasons for Biopharmaceutical Labs to add Mass Detection to Routine Analyses
As regulators focus in on the critical quality attributes (CQAs) of biotherapeutics, what can biopharmaceutical labs in late development or QC do to increase confidence in their bioseparations assays – other than to run additional orthogonal assays? Many labs are finding the answer in mass detection, specifically with the ACQUITY QDa Detector from Waters. Here are three ways that mass ...
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The scientific basis for probiotic strains of Lactobacillus
The concept of using Lactobacillus species for disease treatment and prevention as well as health restoration and maintenance is not new. However, in recent times, there has been a renewal of interest in the use of probiotics (as distinct from antibiotics) (also termed biotherapeutic agents), driven in large part by consumers and the lay press. Probiotics have been used therapeutically to ...
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An Inflection Point for Biopharmaceutical Host Cell Protein Analysis
Has LC-MS Become a Generally Accepted Tool for Complementing Immunoassay-based HCP Analysis? My colleague Catalin Doneanu and I just returned from Lisbon, Portugal, where we attended the BEBPA Conference on Host Cell Protein (HCP) analysis. Along with the other 120 attendees, we participated in open and thoughtful discussions on the best practices for HCP analysis using conventional ...
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Human Microbiome Research Promotes Progress of Precision Medicine
A large part of bacterial, archaeal, viral, and fungal microbial taxa consists of the human microbiome. While many of these microorganisms are commensal, some are harmful to humans and many are symbiotic. Our livelihoods are strongly intertwined with the microbes we allocate our bodies with, regardless of whether their appearance is advantageous, insignificant, or harmful. Over the past few ...
By CD Genomics
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Rani Therapeutics offers breakthrough capsule for patients with chronic conditions
Rani Therapeutics offers a breakthrough capsule, the RaniPill which could change the way patients with chronic conditions take medication by eliminating the need for painful injections. Rani Therapeutics is a clinical-stage biotherapeutics company offering an alternative to painful injections for patients with chronic conditions such as neuroendocrine tumours(NETS). The company based in ...
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Israeli scientists: Cure for insulin-dependent diabetics within five years
A team of Jerusalem-based researchers and entrepreneurs claim they have a cure for diabetesthat could hit the market as early as within the next few years. Betalin Therapeutics has developed the first bio-artificial pancreas, composed of pig’s lung tissue and insulin secreting cells. The artificial pancreas would be implanted into the patient and connect with his or her blood vessels, ...
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Evaluating Microbiome Therapies with Intestinal Cell Models
The microbiome has been shown to play roles in many different disease processes and is implicated in many more, from infectious and gastrointestinal diseases to autoimmune and neurological disorders. Advanced models of the gut leveraging intestinal and colonic stem cells are enabling the development of more reliable and robust systems for evaluating the impact of changes in the microbiome on gut ...
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Lactobacillus paracasei KBL382 administration attenuates atopic dermatitis by modulating immune response and gut microbiota
ABSTRACT Administration of probiotics has been linked to immune regulation and changes in gut microbiota composition, with effects on atopic dermatitis (AD). In this study, we investigated amelioration of the symptoms of AD using Lactobacillus paracaseiKBL382 isolated from the feces of healthy Koreans. Mice with Dermatophagoides farinaeextract (DFE)-induced AD were fed 1 × 109 CFU ...
By KoBioLabs
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