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Bone Morphogenetic Articles & Analysis

5 articles found

Uses of Recombinant Human Collagen

Uses of Recombinant Human Collagen

Recombinant human collagens are an efficient scaffold for bone repair when combined with a recombinant bone morphogenetic protein in a porous, sponge-like format, and when presented as a membrane, sponge or gel can serve as a basis for the engineering of skin, cartilage and periodontal ligament [2]. ...

ByAlfa Chemistry


Development of mRNA-Directed Delivery - LNP Delivery System

Development of mRNA-Directed Delivery - LNP Delivery System

It has been reported that LNPs loaded with siRNA can be systematically delivered to the bone marrow, but passive diffusion still presents a challenge for bone-targeted drug delivery. ...

ByBOC Sciences


Polysaccharides Function as Backbone for Embryonic Osteogenesis

Polysaccharides Function as Backbone for Embryonic Osteogenesis

Osteogenesis, or new bone formation, begins in the early stages of embryonic development and continues postnatally until skeletal maturity is reached in early adulthood. Osteogenesis reoccurs in the event of bone trauma, such as a fracture or surgically created defect. Bone mass can also increase in response to chronic weight bearing from daily use or decrease due to a lack of movement or applied ...

ByMolecular Matrix, Inc.


Fabrication of large diameter TiO<div style="display : inline; font-size:xx-small;">2</div> nanotube for bone morphogenetic protein–2 delivery

Fabrication of large diameter TiO<div style="display : inline; font-size:xx-small;">2</div> nanotube for bone morphogenetic protein–2 delivery

A localised and release–controlled carrier is essential to enhance the effectiveness of bone morphogenetic protein in bone regeneration and repair. In this work, TiO2 nanotubes with diameter larger than 350 nm were successfully fabricated for the first time by electrochemical method using diethylene glycol electrolyte. The diameter of the ...

ByInderscience Publishers


Transforming growth factor &#946;-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth

Transforming growth factor &#946;-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth

The prevalence of these mixed R-Smad complexes explains why TGF-β-induced Smad1/5 phosphorylation does not result in transcriptional activation via bone morphogenetic protein (BMP)-responsive elements, which bind activated Smad1/5-Smad4 complexes that are induced by BMP stimulation. ...

ByAmerican Society for Microbiology (ASM)

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