bone repair Articles
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Hydrothermal synthesis of coccolith rich chalk to hydroxyapatite
Calcium carbonates originating from marine sources show unique pore structure and nano–architecture, offering potential in the field of hard tissue engineering. It is hypothesised that the use of naturally–sourced raw materials for the synthesis of hydroxyapatite (HA), as a component of a hard tissue constructs, enables enhanced bone remodelling due to the biomimetic physical–chemical ...
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Fabrication of large diameter TiO
2nanotube for bone morphogenetic protein–2 deliveryA localised and release–controlled carrier is essential to enhance the effectiveness of bone morphogenetic protein in bone regeneration and repair. In this work, TiO2 nanotubes with diameter larger than 350 nm were successfully fabricated for the first time by electrochemical method using diethylene glycol electrolyte. The diameter of the nanotubes reaches 550 nm and 680 nm at 90 V and 100 V, ...
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Mesenchymal Stem Cell Microenvironment
Mesenchymal stem cells (MSC) differentiate towards multiple lineages that participate in bone formation and are often utilized for bone regeneration therapy. A 2019 review by Lee et al. explores the endogenous mechanical and biochemical environment of MSCs. Additionally, the article highlights the essential factors that lead to bone repair and how these factors can be leveraged to improve bone ...
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Uses of Recombinant Human Collagen
Collagen is the main structural protein in vertebrates. It plays an essential role in providing a scaffold for cellular support and thereby affecting cell attachment, migration, proliferation, differentiation, and survival. Natural animal collagen and its recombinant collagen are favorable replacements in human tissue engineering due to their remarkable biomedical property. However, this ...
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Bridging Art & Science: EpiBone’s First Artist in Residence
What is an artist doing working in a cutting-edge science lab? That’s a question I hear almost every time I explain my summer internship at EpiBone. Fortunately, I feel my whole life has been preparing me to answer it. I have always sat firmly at the intersection between art and science. My best subjects in school were the visual arts and the natural sciences, a seemingly unlikely pair. ...
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Useful Information of Machined Tantalum
Tantalum was discovered by Swedish chemist A.G. Ekeberg in 1802, it is mainly present in tantalite and co-exists with niobium. Tantalum has moderate hardness and is full of ductility and can be drawn into filament thin foil. Tantalum has excellent chemical properties and very high corrosion resistance; it also has high melting point. Due to its excellent corrosion resistance, tantalum is widely ...
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3D Bioprinting Of Prevascularised Implants For The Repair Of Critically-Sized Bone Defects
By combining different cell populations in a fibrin bioink, researchers from Trinity College Dublin, Royal College of Surgeons in Ireland and University of Illinois Chicago were able to sprout an in vitro microvessel network that was then exploited to prevascularise a 3D printed scaffold implanted in a critical size femoral defect using REGENHU bioprinter. This dual approach was observed to ...
By Regenhu
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Field Orthopaedics gets FDA approval for world’s smallest orthopaedic screw
The Brisbane-based designer of the world’s smallest orthopaedic screw has invoiced US hospital suppliers $900,000 in the three weeks since the device gained Food & Drug Administration approval, and he hopes it can soon be made in Brisbane too. Field Orthopaedics, founded in 2016 by former Army doctor Chris Jeffery alongside a team of doctors and engineers including hand surgeon Greg ...
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90+ reasons to smile
What happens when you bring 90+ expert dentistry and maxillofacial surgeon’s together in a room to unpack the burgeoning world of collagen membrane technology and digital dentistry? There are plenty of reasons to smile, that’s what. On Tuesday 7 August 2018, Australian regenerative medicine company Orthocell (ASX:OCC) sponsored and participated in an industry forum, Advances in ...
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Polysaccharides Function as Backbone for Embryonic Osteogenesis
Osteogenesis, or new bone formation, begins in the early stages of embryonic development and continues postnatally until skeletal maturity is reached in early adulthood. Osteogenesis reoccurs in the event of bone trauma, such as a fracture or surgically created defect. Bone mass can also increase in response to chronic weight bearing from daily use or decrease due to a lack of movement or applied ...
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