brain barrier Articles
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Brain region distribution and patterns of bioaccumulative perfluoroalkyl carboxylates and sulfonates in East Greenland polar bears (Ursus maritimus)
The present study investigated the comparative accumulation of perfluoroalkyl acids (PFAAs) in eight brain regions of polar bears (Ursus maritimus, n = 19) collected in 2006 from Scoresby Sound, East Greenland. The PFAAs studied were perfluoroalkyl carboxylates (PFCAs, C6–C15 chain lengths) and sulfonates (C4, C6, C8, and C10 chain lengths) as well as selected precursors including ...
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Nuclear factor I-A regulates diverse reactive astrocyte responses after CNS injury
Abstract Reactive astrocytes are associated with every form of neurological injury. Despite their ubiquity, the molecular mechanisms controlling their production and diverse functions remain poorly defined. Because many features of astrocyte development are recapitulated in reactive astrocytes, we investigated the role of nuclear factor I-A (NFIA), a key transcriptional regulator of astrocyte ...
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Nature: Why do you just want to lie down when you get sick?
When we feel uncomfortable, we tend to eat less, drink less, and exercise less. This is not unique to humans—most animals reduce these three behaviors when fighting infection. Recently, a new study pinpoints clusters of neurons that control these responses (uncomfortable behavior). By provoking immune responses in mice, the researchers demonstrated that specific cell populations in the ...
By CD BioGlyco.
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Cell-Penetrating Peptides: Features, Mechanisms, Applications
Cell-penetrating peptides (CPPs) refer to water-soluble, partly hydrophobic, and/or polybasic short peptides that are fewer than 30 amino acids in size. Different types of CPPs like chimeric peptides and hydrophobic peptides have different lengths, charges, solubility, and hydrophobicity. At current, cell-penetrating peptides are often classified in line with their characteristics, including ...
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Health Mythbusting: Does eating turkey really make you tired?
This holiday season, Americans will consume around 87 million turkeys. And after they gobble down their turkey dinners, they might experience post-meal sleepiness. Often, people blame turkey as the cause. But does turkey actually make you tired? Why? What's in it? And what other factors are at play? In today’s article, we’ll break down the health myth of whether eating ...
By Evidation
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FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer
Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a relatively rare and dangerous subtype, with patients suffering from a high incidence rate of brain metastases. Statistics show that about 55% of ALK-positive advanced NSCLC patients will develop brain metastases during ...
By BOC Sciences
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Dissolved Hydrogen Application
Hydrogen molecule is the smallest molecule in nature. It is extremely penetrating and extremely volatile. It can freely enter and exit the body cells, remove aging and toxic free radicals. After drinking, it enters human body tissues and diffuses to act on all organ line particles and nucleus. Absorbed by the body. Realize the balance of the environment in the body and initiate the mechanism of ...
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Intracranial Neoplasms: The Evolution of Radiotherapies
CURRENT STANDARD OF CARE FOR BRAIN TUMORS The current initial standard of care for aggressive brain tumors—whether they are primary brain tumors (ie, tumors that originate in the brain), or metastatic tumors from cancers that started outside of the brain—is resection. After surgery, a follow-up treatment, also referred to as adjuvant treatment, is often recommended to help eliminate ...
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Unlocking the potential of collaborative neurotrauma research: Interview with BrainQ CSO and Co-founder, Prof. Esty Shohami
The phrase “not all heroes wear capes” springs to mind when speaking with BrainQ’s Chief Scientific Officer (CSO) and Co-founder, Prof. Esther Shohami. A world-renowned expert and pioneer in neurotrauma research, Esty utilizes her vast experience to direct the development and implementation of the company’s scientific and research operations. But that’s just the ...
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Nanobodies Definition, Structure, Advantages and Applications
What is a Nanobody?Nanobodies are the smallest functional single-domain antibodies known to be able to stably bind to antigens, and have unique structural and functional advantages. The molecular weight of nanobodies is only 12-15 kDa, which retains the antigen binding ability of traditional antibodies. However, nanobodies have higher solubility and stability, and have unique advantages in ...
By BOC Sciences
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Chemyx Syringe Pumps in Neuroscience Research
Introduction The classical field of neuroscience entails biological or psychological investigation of the nervous system, including the brain, spinal cord and the systemic network of sensory nerve cells called neurons.1 Traditionally, this field comprised of purely biological studies but has since flourished into an interdisciplinary sphere addressing the developmental, physiological, ...
By Chemyx Inc
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The Key Technology of RNA Therapy
It is certain that RNA therapy is no longer a no-man's land for medical innovation. Not only have several products been launched and received good market response, but there are also many pipelines in the research and development side to advance to the middle and late clinical stage, and behind the boom are the technological breakthroughs of scientists. There are three key points in the ...
By BOC Sciences
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AstaPure® EyeQ: Natural astaxanthin for Eyes and brain - Download the eBook!
Inspired by the superb vision and natural mechanism of the eagle's eye, Algatechnologies introduces AstaPure® EyeQ. a clinically supported, microencapsulated, cold water-soluble 2% natural astaxanthin powder. AstaPure® EyeQ is a highly pure extract derived from Haematococcus pluvialis microalgaer a species of microalgae known to be the richest source of natural astaxanthin. As a ...
By Algatech
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CanaQuest Medical Corp (OTC: CANQF)
About: CanaQuest Medical is an award-winning, Clinical Stage/Life-Sciences company focused on the drug discovery and development of next-generation targeted therapeutics within the endocannabinoid system and specific brain receptors. The Company is focused on treating neurological conditions, such as epilepsy, anxiety, depression, and Post Traumatic Stress Disorder “PTSD,” including ...
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What happens to your brain during a concussion?
Over the last few decades, scientists have gained a much better understanding of what happens to your brain during a concussion. It’s allowed them to understand better the devastating effects that a traumatic brain injury can have, and how to treat them properly. Unfortunately, the general public does not understand how nasty a concussion can be. To gain a better appreciation, you can start ...
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