brain heart Articles
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Faecalibacillus intestinalis gen. nov., sp. nov. and Faecalibacillus faecis sp. nov., isolated from human faeces.
Abstract Two long-rod-shaped, Gram-stain-positive, obligately anaerobic and non-spore-forming strains, SNUG30099T and SNUG30370T, were isolated from faecal samples of healthy Korean subjects. The strains formed circular ivory-coloured colonies on Brain-heart infusion medium supplemented with 0.5% Difco yeast extract (YBHI) agar and cells were approximately 3.5-4.5×0.3-0.4 µm ...
By KoBioLabs
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What Are the Applications of Enzymes in Disease Research and Treatment?
With the development of biotechnology in the modern information age, the research, development and utilization of enzymes have become more and more in-depth, and correspondingly, the application of enzymes in medicine has become more and more extensive. 1. The relationship between enzymes and certain diseases The diseases caused by the lack of enzymes in the human body are mostly congenital or ...
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The Functions and Roles of Enzymes
Catalysis Enzymes are a class of biological catalysts. They govern many catalytic processes such as metabolism, nutrition, and energy conversion of organisms. Most of the reactions closely related to life processes are enzyme-catalyzed reactions. These properties of the enzyme enable the intricate process of material metabolism in the cell to proceed in an orderly manner, and to adapt material ...
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Catalase, a Common Antioxidant Enzyme
Catalase is an antioxidant enzyme commonly found in almost all living organisms, mainly in chloroplasts, mitochondria, endoplasmic reticulum of plants, liver and red blood cells of animals. It is the marker enzyme of the peroxisome, accounting for about 40% of the total peroxisomal enzymes. Catalase is a homotetramer composed of four polypeptide chains, each containing more than 500 amino acid ...
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Subacute toxicity of selenium sources in mice
Sixteen groups of mice were fed diets containing different selenium species to compare their toxicity. Inorganic sodium selenate and sodium hydroselenite, elementary nanoSe, organic Sel‐Plex, and Lacto‐MicroSelenium were administered for 14 d at concentrations of 0.5, 5, and 50 ppm Se, equivalent to 0.5, 5, and 50 mg Se/kg food, corresponding to an estimated 4, 40, and 400 µg/kg bw/d Se uptake, ...
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Harnessing the utility of autoantibodies to overcome challenges associated with clinical development in Systemic Lupus Erythematosus (SLE)
Overcoming issues of heterogeneity in disease classification and enabling new approaches to successful drug development. SLE is an autoimmune disease with a wide range of clinical manifestations. It affects approximately 5 million people worldwide and its prevalence varies in different geographies. SLE accounts for around 70% of all cases of lupus, other forms being cutaneous lupus, ...
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Repression of prespliceosome complex formation at two distinct steps by fox-1/fox-2 proteins
Precise and robust regulation of alternative splicing provides cells with an essential means of gene expression control. However, the mechanisms that ensure the tight control of tissue-specific alternative splicing are not well understood. It has been demonstrated that robust regulation often results from the contributions of multiple factors to one particular splicing pathway. We report here a ...
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New Findings about BRD4 Protein You May Want to Know
A new study clarifies how BRD4 (a protein that scientists have studied for many years) directs the spatial organization of DNA in the cell nucleus (a key function of stem cells to differentiate into muscle cells), which promotes the understanding of certain cancers and complex congenital diseases. Since the way DNA is folded is essential for gene regulation, this research not only has ...
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BOHS cautions that new research into occupational exposure to diesel for professional drivers highlights a COVID-19 dilemma with ventilation
BOHS welcomes new research by IOSH-sponsored Imperial College into occupational exposure to diesel for professional drivers, but cautions that it highlights a COVID-19 dilemma with ventilation. The British Occupational Hygiene Society, a scientific charity and the Chartered Society for Workplace Health Protection, is welcoming research published by Imperial College London’s ...
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What are Cannabinoids?
The term “cannabinoids” originally described bioactive constituents of the plant Cannabis sativa, a plant that can grow wild in mild, tropical climates around the world. For centuries, the cannabis ingredients were used traditionally for their medicinal purpose but also for their recreational properties; however, only since the 1940s have cannabinoids been purified from cannabis ...
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Organoid Models of SARS-CoV-2 Infection learned from COVID-19
The clinical presentation of COVID-19-related illness ranges from asymptomatic to mild respiratory symptoms resembling influenza infection to acute symptoms including pneumonia requiring hospitalization and admission to the intensive care unit. COVID-19 starts in the upper airways and lungs, but in severe cases can also affect the heart, blood vessels, brain, liver, kidneys, and intestines. ...
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Vaginal lactobacilli inhibit growth and hyphae formation of Candida albicans
Abstract Lactobacillusspecies are the predominant vaginal microbiota found in healthy women of reproductive age and help to prevent pathogen infection by producing lactic acid, H2O2 and anti-microbial compounds. Identification of novel vaginalLactobacillus isolates that exhibit efficient colonisation and secrete anti-Candida factors is a promising strategy to prevent vulvovaginal candidiasis. ...
By KoBioLabs
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AI’s Evolving Role in Monitoring and Treating Sleep Disorders
Obstructive sleep apnea (OSA) is a serious and life-threatening condition. Approximately 5.9 million adults are diagnosed with OSA, but as many as 23 million people are estimated to be dealing with OSA yet go undiagnosed. The impact on health can be significant, ranging from inconveniences to life-threatening illnesses. Obstructive sleep apnea can cause disrupted sleep for both OSA sufferers and ...
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Landmark study confirms that controlled blood pressure is key to prevent stroke, heart disease
Follow-up data from the landmark SPRINT study of the effect of high blood pressure on cardiovascular disease have confirmed that aggressive blood pressure management — lowering systolic blood pressure to less than 120 mm Hg — dramatically reduces the risk of heart disease, stroke, and death from these diseases, as well as death from all causes, compared to lowering ...
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