brain tissue Articles
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Cercare Perfusion Reveals Microvascular Changes in COVID-19 - Case Study
Introduction Neurologic complications are frequently reported in COVID-19, but our understanding of their pathophysiologic causes and neuroanatomical correlates is limited. While several structural brain imaging findings have been reported in COVID-19, including non-spherical signal abnormalities on Susceptibility-Weighted Imaging (SWI), conventional perfusion imaging has not provided consistent ...
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The endocrine effects of dietary BDE‐47 exposure, measured across multiple levels of biological organization, in breeding fathead minnows
The goal of the present study was to evaluate the reproductive function of fathead minnows (Pimephales promelas) exposed to brominated diphenyl ether 47 (BDE‐47) at doses lower than used in previous studies. This was accomplished by evaluating the impacts of BDE‐47 exposures across multiple levels of biological organization. Breeding pairs were exposed to BDE‐47 via diet for 21 days during ...
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Ischemic Stroke: The First Pass Effect
It's been less than five years since, beginning with MR CLEAN, a series of landmark trials validated the role of clot-removing (thrombectomy) devices that can open up large vessel occlusions in the anterior circulation of patients experiencing acute ischemic stroke. But the field is moving fast. Mechanical thrombectomy devices known as stent retrievers (or stentrievers) and aspiration catheters ...
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Evaluation of Anti-Stroke Drugs
Stroke, also known as transient ischemic attack or cerebrovascular accident, is an acute brain disease. Usually, a sudden rupture of a blood vessel in the brain or a blockage of a blood vessel that prevents blood from flowing to the brain can cause damage to brain tissue, resulting in a stroke. Long-term strokes can lead to brain damage, disability and even death. The brain serves as a ...
By Protheragen
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CD Genomics Perspective: RNA Sequencing, A Powerful Method for Studying Various Diseases
Although post-mortem brains have been frequently reported as the "gold standard" in transcriptomic research for ND and neuropsychiatric abnormalities, the main sources has been mRNA separated from transgenic animal models and, more lately, patient-derived cell lines. However, despite their promise, transcriptome studies are difficult due to the obvious difficulties in obtaining brain tissue and ...
By CD Genomics
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Sublethal propoxur toxicity to juvenile common carp (Cyprinus carpio L., 1758): Biochemical, hematological, histopathological, and genotoxicity effects
The sublethal toxicological and genotoxic potential of propoxur, a widely used carbamate insecticide against household pests, in veterinary medicine, and in public health, was evaluated on carp as a model species (Cyprinus carpio L., 1758) using the erythrocyte micronucleus test. Based on the 96‐h lethal concentration, 50% (LC50) data from the U.S. Environmental Protection Agency ECOTOX Database ...
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Do you really have to sacrifice MRI image quality for speed?
To understand the significance of the SpinTech MRI STAGE software platform, it helps to begin by asking a question: Given that MRI is an incredibly powerful diagnostic tool for neurological diseases like Alzheimer’s, dementia, Parkinson’s and multiple sclerosis (MS), why have radiologists and neurologists had to choose between conducting faster MRI exams and obtaining higher-quality ...
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What happens to your brain during a concussion?
Over the last few decades, scientists have gained a much better understanding of what happens to your brain during a concussion. It’s allowed them to understand better the devastating effects that a traumatic brain injury can have, and how to treat them properly. Unfortunately, the general public does not understand how nasty a concussion can be. To gain a better appreciation, you can start ...
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Construction and Culture Protocol of Neural Stem Cells Protocol
Because neural stem cells (NSCs) have the potential of self-renewal and multidirectional differentiation, the method of suspended neural bulb culture can be used to obtain and study. After processing the embryonic brain tissue into a single cell, only the cells with the ability of self-renewal can be cloned and proliferated into a suspended nerve ball in the culture medium, and with the progress ...
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Custom fit helmets – can they help protect against concussions?
It appears that high-contact sports such as hockey and football are becoming much more violent. Although both sports have made efforts to remove unnecessary hits from the game, concussions are inevitable when athletes are as strong and fast as they are today. The only reasonable solution is to improve the safety equipment the players use in hopes of protecting them from a traumatic brain ...
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Intracranial Neoplasms: The Evolution of Radiotherapies
CURRENT STANDARD OF CARE FOR BRAIN TUMORS The current initial standard of care for aggressive brain tumors—whether they are primary brain tumors (ie, tumors that originate in the brain), or metastatic tumors from cancers that started outside of the brain—is resection. After surgery, a follow-up treatment, also referred to as adjuvant treatment, is often recommended to help eliminate ...
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Nature: Structure-based classification of tauopathies
Abnormal accumulation of misfolded tau in filaments is characteristic of many neurodegenerative diseases—precisely for this reason, these neurodegenerative diseases are collectively referred to as tauopathy. The Michel Goedert team and the Sjors Scheres team at the Molecular Biology Laboratory of the Medical Research Council in Cambridge, UK, witnessed the use of cryo-EM to dissect tau ...
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ZAP Surgical Announces First Facility on the East Coast Initiates Patient Treatment Using New Non-Invasive Brain Tumor Therapy
ZAP Surgical Systems, Inc. today announced ZAP-X® Gyroscopic Radiosurgery® patient treatments have commenced at MedStar Georgetown Cancer Institute at MedStar Southern Maryland Hospital Center in Clinton, MD. For many primary and metastatic brain tumors, stereotactic radiosurgery (SRS) has proven to be an effective treatment with outcomes equivalent to invasive surgical procedures. ...
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New Approach to Successfully Purify and Characterize Human Neural Stem Cells
Human brain has approximately 171 billion cells, of which slightly more than half (approximately 86 billion) are nerve cells. These 86 billion nerve cells are a diverse cell population with hundreds of specialized types and functions, but all originate from three neural cell lineages--neurons, oligodendrocytes, and astrocytes. All three cell lineages originate from a pool of neural stem and ...
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Oxygen therapy for neurology
A prematurely aged brain has suffered years of abuse from our ever-increasingly toxic environment and unhealthy lifestyles. There is extensive research that shows HBOT may have an effect in rejuvenating a patient’s brain by stimulating the production of new blood vessels. Increased oxygen in the blood flow will re-energize dormant cells in the brain and create new ones. Oxygen to ...
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The journey of stroke recovery in 2021
Stroke is one of the most devastating and most prominent causes of disability around the globe, with 800,000 new cases each year in the US alone. During a stroke, the brain experiences an interruption in blood supply, which prevents the brain tissue from receiving the oxygen it needs to function properly. The most prevalent type of stroke is an ischemic stroke, which happens when a vessel that ...
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The impact of robotics on neurosurgery
Stuart Campbell, Clinical Sales Development Manager of the Neurological Products Division at Renishaw, discusses key trends on the use of robotics in neurosurgery. The curious case of Phineas Gage is one of the earliest and best known cases of serious brain injury. On September 13th, 1848, Gage was working as a railway foreman in Vermont when an explosion caused a three foot long iron rod to be ...
By Renishaw plc
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FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer
Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a relatively rare and dangerous subtype, with patients suffering from a high incidence rate of brain metastases. Statistics show that about 55% of ALK-positive advanced NSCLC patients will develop brain metastases during ...
By BOC Sciences
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ODS Medical joins forces with two American Giants
ODS Medical will undertake within a few weeks the first official clinical trial which will allow it to test its surgical probe, a tool capable of discerning, in real time, cancerous tissue from healthy tissue in brain operated patients. But before arriving there, she chose to surround herself well. The company has just signed an agreement with an American medical equipment manufacturer whose ...
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The 7-Steps to Recuperation from Stroke Arm Paralysis
About two-thirds of those that experience arm paralysis after stroke are unable to fully use their affected limb six months after stroke (1-3). Not having a fully functional arm and hand after a stroke is not only frustrating but also devastating to many individuals. Day-to-day operations and activities of daily living become more difficult, take longer to complete, and may require assistance ...
By Neurolutions
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