cancer diagnoses Articles
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Zanidatamab, a HER2-targeted bispecific antibody, in combination with docetaxel as first-line therapy for patients with advanced HER2-positive breast cancer: Preliminary results from a Phase 1b/2 study (American Society of Clinical Oncology)
Worldwide, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in women, with over 650,000 deaths in 2020.1,2 Human epidermal growth factor receptor 2 (HER2)-targeted agents have improved outcomes in HER2-positive breast cancer, but most patients in first-line therapy do not respond to current therapies, eventually relapse or develop ...
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Low-dose irradiation for controlling prostate cancer
Prostate cancer is the second most commonly diagnosed cancer among North American men and the second leading cause of death in those aged 65 and over. The US Cancer Society recommends testing those over 50 years of age who are expected to live at least for 10 years, even though the ability of early detection to decrease prostate cancer mortality has not been demonstrated. A controversy exists ...
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Enhancing Oncology Model: New CMS value-based payment model aims to improve health equity and patient-centered care
Just days before the sunset of the CMS Oncology Care Model, CMS announced its new Enhancing Oncology Model (EOM), the new value-based care oncology payment model. Rolled out as part of the Biden-Harris Administration’s Cancer Moonshot, the goal of EOM is to improve the experience of cancer patients, while advancing health equity and increasing access to care, as well as reducing Medicare ...
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The Limitations and Challenges of Cancer Therapies
Considerable investment into cancer research has led to the development of remarkable new therapies, which have greatly improved therapeutic outcome for the countless individuals diagnosed with cancer. Until recently, almost all therapies that were granted clinical approval were small molecules. However, biotechnological advances in the last several decades have made it possible to develop ...
By Indee Labs
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New Breast Imaging Technology: The Koning Difference
Revolutionizing breast cancer detection Breast cancer is the most diagnosed cancer in women in the United States and the second leading cause of cancer death in American women.1 It is also treatable if detected early enough. While there are various cancer detection modalities available, current breast imaging devices fail to expose as much as 35% of breast cancers and that number increases to ...
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How Has the COVID-19 Pandemic Affected Prostate Cancer Care?
#CancelEverything On March 11, 2020, the World Health Organization (WHO) declared the coronavirus 2019 disease (COVID-19) a global pandemic. Its impact left the world uncertain about health, politics and the economy. The first wave caused a major disruption to health services, exacerbating concerns of patient and physician safety and resource availability. On trend with the “cancel ...
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Novel Tumor Bed Marking in Breast Cancer: Expanding Beyond Lumpectomy
VeraForm® placement to assist with localization and delivery of adjuvant radiation Historically, lumpectomies resulted in a scar immediately over the lumpectomy site, dictating delivery of adjuvant radiation on scar location, and frequently on the presence of a seroma. Currently, the question persists as to the optimal means to help direct the radiation oncologist to effectively deliver ...
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Bilateral Insufficiency Fractures in an Oncology Patient Treatment with the CurvaFix IM System - Case Study
CASE PRESENTATION A 70-year-old female recently diagnosed with metastatic pancreatic cancer presented with acute new onset of lower back pain. The patient was taking chemotherapy, participating in a drug therapy trial, and had received radiation therapy. There was no history of acute trauma to the pelvic or acetabular region. Magnetic resonance imaging revealed bilateral fragility fractures, with ...
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Ensuring the safe use of MRI scanners
Hospitals throughout the world, working towards improving the lives and outcomes for cancer sufferers, are using MRI (magnetic resonance imaging) scanners to diagnose and stage cancer in patients. Whilst the magnetic fields and radio waves used by MRI scanners pose no risk to humans, scanners’ cooling system potentially do, and careful installation and maintenance is essential to ensure ...
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Movember Together: How Paige, University of Oxford, and Prostate Cancer UK Are Working to Change the Prostate Cancer Experience
Movember is an annual initiative where men from around the globe grow mustaches to raise awareness for men’s health causes, including mental health and suicide prevention, testicular cancer, and prostate cancer. Through events, fundraising, and using mustaches as a light-hearted starting point for important conversations, the movement supports men in taking charge of their health to live ...
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Modified bacteria produce tetanus toxin, which is utilized to treat fatal pancreatic cancer
Pancreatic cancer is a highly malignant tumor of the digestive tract that is difficult to diagnose and treat, and the morbidity and mortality rates have risen dramatically in recent years. Pancreatic cancer is at an advanced stage when diagnosed when cancer cells have spread and are hard to control. The most frequent pancreatic cancer is pancreatic ductal adenocarcinoma (PDAC), accounting for ...
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Nanostics Announces the Launch of its Bladder Cancer Clinical Study Identifying Disease Predictors for Early Detection of Bladder Cancer
Clinical study launched in June 2022 with patient recruitment in Alberta with plans to expand to further sites across North America. The aim of the study is to validate a novel and minimally invasive liquid biopsy test for bladder cancer diagnosis using Nanostics’ ClarityDX® diagnostic platform. The study is supported in part by the Alberta Innovates AICE-Concepts Program with a ...
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Bio-tech firm recruiting Yukon men for trial, Prostate cancer group says it could save lives
The Yukon chapter of Ride For Dad says a new blood test developed by an Alberta-based company could save the lives of men at risk of prostate cancer. (iStock/Getty Images) A bio-technology company based in Alberta is testing a new process that could result in fewer Yukon men travelling out of territory for prostate cancer biopsies. Private research company Nanostics Inc. and the University of ...
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Enzymes for Disease Diagnosis: An Overview
Enzymes are protein molecules that catalyze chemical reactions in living organisms. They are involved in many metabolic processes and play a critical role in maintaining the health of the body. In recent years, enzymes have been widely used in disease diagnosis, providing a quick and accurate way to detect and monitor diseases. Enzymes for disease diagnosis can be divided into two categories: ...
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Methylation Markers of Pancreatic Cancer categorization and prognosis evaluation
Background Pancreatic cancer is one of the highest mortality rate cancers worldwide with 5-year relative survival of 10.8%. Lack of screening methods for early-stage detection as well as proper patient sub-characterization, make it a fatal cancer due to poor diagnoses and insufficient treatment. Methylation flags are kept on tumorigenesis, akin to the tissue-specific traces that are acquired and ...
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Analytical Approaches and Applications of Whole Exome Sequencing (WES) in Oncology
Introduction Genomics has revolutionized cancer research, transforming the way we diagnose, treat, and monitor cancer. Among the powerful genetic analysis methods, Whole Exome Sequencing (WES) stands out as a cutting-edge technique that employs sequence capture technology to enrich DNA from the whole exome regions, enabling high-throughput sequencing. WES offers a simpler, more cost-effective, ...
By CD Genomics
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The Danish National Genome Center Partners with Lifebit to Deliver Nationwide Personalised Medicine
The Danish National Genome Center has awarded Lifebit a four-year contract to implement Lifebit’s Federated Trusted Research Environment software, Lifebit CloudOS, within Denmark's national supercomputing center. LONDON, UK - 28 April 2022 – Lifebit, whose leading technology enables secure analysis over sensitive datasets for researchers and interconnects such large patient cohorts ...
By Lifebit
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5 year trial involving ovarian cancer patients has found “overall survival benefits” when undergoing surgery using PlasmaJet
A trial involving ovarian cancer patients at Guildford’s Royal Surrey Hospital (UK) has found they have a higher chance of having all the tumour removed when undergoing surgery using argon plasma. Patients who participated in the ‘PlasmaJet® in Ovarian Cancer Surgery’ feasibility study were given a preview of the results as part of Ovarian Cancer Awareness Month recently. ...
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Why open-source AI platforms are the future of patient health tracking in clinical trials
Imagine you’ve just been diagnosed with cancer and you’re enrolled in a clinical trial for a promising new drug. You notice that after chemotherapy you struggle with occasional fatigue. Yet, whenever you visit your doctor every couple of weeks, you feel fine. This is not only a frustrating experience for patients, but it can also compromise the safety data in a clinical trial. The ...
By AiCure
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Link Between Periodontal Disease and Oral Cancer
There is a strong relationship between periodontal disease and oral cancer. In patients with tongue cancer, the periodontal disease preceded the tongue cancer. Although periodontal disease and oral cancers are both located in the mouth, until recently, there was never thought to be a connection between the two. New evidence is coming to light to show that those with periodontal disease increase ...
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