cancer patient Articles
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Low doses of γ–radiation induce consistent protein expression changes in human leukocytes
Twenty percent of cancer patients experience adverse effects after radiotherapy. The therapeutic doses are adjusted to the most sensitive individuals, resulting in a suboptimal dose for many patients. At present there is no screening system available to predict individual radiosensitivity. The main aim of this study is to investigate differences in protein expression pathways induced by low doses ...
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OneThree’s Workflow for Identifying Synergistic Drug Combinations - Case study
Background OneThree Biotech was born out of the largest precision medicine institute in America with the purpose of decreasing the failure rate of bringing therapeutics to market using biology driven artificial intelligence. Our technology was builtin a lab setting; allowing us to engineer our methodologies around real-world results. While working with major biotech and pharma partners; ...
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Building personalized treatment plans for early-stage colorectal cancer patients
Abstract We developed a series of models to predict the likelihood of recurrence and the response to chemotherapy for the personalized treatment of stage I and II colorectal cancer patients. A recurrence prediction model was developed from 235 stage I/II patients. The model successfully distinguished between high-risk and low-risk groups, with a hazard ratio of recurrence of 4.66 (p < ...
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The development of complete personalized treatment plans for colon cancer patients utilizing three gene prediction models.
Background Combination chemotherapy using fluorouracil, leucovorin with or without oxaliplatin (5-FU and FOLFOX) are standard treatment for locally advanced colon cancer. However, about half of the patients developed recurrence. The objective of this study was to use gene profiling to predict treatment efficacy for colon cancer patients (stages 1-3). We developed three prediction models: the ...
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How To Use TCM Pain Relief Patch Correctly?
TCM(Traditional Chinese Medicine) pain relief patches have a very good effect on alleviating cancer pain. Note that the traditional Chinese medicine analgesic patch cannot treat cancer, but it has a very obvious pain relief effect on neuropathic pain, muscle pain, body organ pain, and Google pain caused by cancer. Some cancer patients may experience aggravated pain when they use traditional ...
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Impact of low anterior resection syndrome (LARS) on quality of life
Low anterior resection syndrome (LARS) has a substantial negative impact on quality of life and almost 70% of patients experienced major LARS 1-11 years after rectal surgery. Rectal cancer patients experience symptoms of low anterior resection syndrome (LARS) several years after their rectal surgery with a substantial impact on quality of life (QoL) as shown in this observational cohort study. ...
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ADC Drugs For Breast Cancer Treatment
Breast cancer is the malignant tumor with the highest morbidity and mortality among women worldwide. At present, the main therapeutic methods include surgery, chemotherapy, radiotherapy, endocrine therapy and targeted therapy, etc. The development and marketing of new drugs have far-reaching significance in improving the survival of breast cancer patients and changing the pattern of breast cancer ...
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Researchers highlight the impact of COVID 19 pandemic on patients with cancer
New collaborative research from Queen’s University Belfast, the University of Split, Croatia and King’s College London has shown that the response to the outbreak of the coronavirus disease 2019 (COVID-19) is significantly affecting the treatment and care of patients with cancer. The research, recently published in the European Journal of Cancer, highlights how the repurposing of ...
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Taking care of personal matters during a mesothelioma lawsuit
Mesothelioma is a very serious disease and, as if this isn't bad enough, the various treatments for mesothelioma can also be very difficult. As a result, anyone with mesothelioma needs assistance and comfort from family members, friends, professionals, support groups and members of the community. It is often helpful to seek the support of a group or organization devoted to the needs of ...
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Project - Development of a free, easy-to-use electronic patient self-reporting outcomes solution to be deployed through our existing platform ONCOassist and made available globally
Project Description We are developing a free, easy-to-use electronic patient self-reporting outcomes solution to be deployed through our existing platform ONCOassist and made available globally. This will improve the quality of patient care and allow life science companies to gather real-world evidence about how their drugs are performing in the field. Cutting edge research shows ...
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Early efficacy signals in ovarian cancer patients in ongoing Ph1 trial: Poster reporting findings presented at SITC 2020 Annual Meeting
ENB Therapeutics reports preliminary data from the ongoing Phase 1/2 trial assessing the safety and efficacy of lead product ENB-003 in combination with pembrolizumab. Safety data are encouraging with no significant drug related safety events from the first 3 dosing cohorts. Best overall responses from the first 6 patients include 2 disease stabilizations and 1 confirmed partial response. The ...
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Ensuring the safe use of MRI scanners
Hospitals throughout the world, working towards improving the lives and outcomes for cancer sufferers, are using MRI (magnetic resonance imaging) scanners to diagnose and stage cancer in patients. Whilst the magnetic fields and radio waves used by MRI scanners pose no risk to humans, scanners’ cooling system potentially do, and careful installation and maintenance is essential to ensure ...
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ADC Drugs For HER2 Positive Breast Cancer
According to the latest data, breast cancer has overtaken lung cancer to become the most common cancer among women, and the death rate is the second highest among female tumors, seriously affecting the physical and mental health of women around the world. Patients with abnormal expression of human epidermal growth factor receptor (HER2) account for 15%-20% of all breast cancers, which is highly ...
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Regulation of cancer by therapeutic vaccination and dietary bio-modulation involving organ-specific mitochondria
Cancer therapy should aim to prevent recurrent disease. Surgery and toxic treatments remove only symptoms associated with cancer without trying to intervene in the aetiology, therefore the disease may recur. The autologous cancer vaccine supplemented with bio-modulation might fulfil requirements for effective tumour therapy. The autologous tumour vaccine is formed in the same way as our bodily ...
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Remote Oncology Care: Review of Current Technology and Future Directions
Abstract Cancer patients frequently develop tumor and treatment-related complications, leading to diminished quality of life, shortened survival, and overutilization of emergency department and hospital services. Outpatient oncology treatment has potential to leave cancer patients unmonitored for long periods while at risk of clinical deterioration which has been exaggerated during the COVID19 ...
By Oncodisc
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Zanidatamab, a HER2-targeted bispecific antibody, in combination with docetaxel as first-line therapy for patients with advanced HER2-positive breast cancer: Preliminary results from a Phase 1b/2 study (American Society of Clinical Oncology)
Worldwide, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in women, with over 650,000 deaths in 2020.1,2 Human epidermal growth factor receptor 2 (HER2)-targeted agents have improved outcomes in HER2-positive breast cancer, but most patients in first-line therapy do not respond to current therapies, eventually relapse or develop ...
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A Combination of Ramucirumab Plus Pembrolizumab Lengthened Survival For Some Lung Cancer Patients
A study conducted under the Lung Cancer Master Protocol (Lung-MAP) found that when treated with a combination of ramuzumab (Cyramza) and Keytruda, Patients with advanced NSCLC whose cancer progressed during prior immunotherapy lived significantly longer than when treated with one of the current standard therapies for this cancer. The hazard ratio (80% confidence interval) for overall survival ...
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New blood-based CRC test is more than 90% accurate, study says
A study of Universal Diagnostics' blood-based colorectal cancer test found it was more than 90 percent accurate, the company announced June 3. The blood test was found to detect colorectal cancer with 92 percent sensitivity and 97 percent specificity. It also was shown to have 89 percent sensitivity and 97 percent specificity detecting early-stage cancer. The test uses single target sequence ...
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Automatically Diagnosing HER2 Amplification Status for Breast Cancer Patients Using Large FISH Images
Fluorescence in situ hybridization (FISH) is a technique that prepares acceptable results for molecular imaging biomarkers to precisely and dependably detect and diagnose disorders which are sign of cancers. Since contemporary manual FISH signal analysis is low-effective and inconsistent, it is an attractive research area to develop automated FISH image scanning systems and computer-aided ...
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Cancer Care Center of York County Sanford, Maine - Case Study
Key Parameters Type of Facility – Existing Build (EB) Function – Healthcare Area – 1-story Oncology and Patient Care Building Project Completed – 2007 Challenge: Clean air is important but it is extremely important for oncology patients. When the facility opened in 2006, the center’s proximity to a nearby rubber plant resulted in odors frequently being ...
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