cancer related Articles
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Carbon nanotube-based electrochemical signal amplification for breast cancer gene detection
Carbon-nanotubes (CNT) represent an important group of nanomaterials with useful properties that enable their use for many important applications and made them extremely attractive for the task of electrochemical detection. Here, the author uses CNT to enhance the sensitivity of a multi-enzyme-based electrochemical bioassay for breast cancer gene (BRCA1) detection. Giant enzyme-based ...
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Oncology - Complex Clinical Trials in The Fastest Growing Therapeutic Area
In the developed world, 1 in 4 people die from cancer or cancer-related disease, and cancer accounts for 13% of deaths globally. Oncology is the fastest growing therapeutic area by revenue and number of clinical trials. There’s been a huge emphasis on developing new treatments to improve survival in patients with cancer, but these trials have become a costly undertaking for sponsor ...
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Through a Simple Blood Test, Our Body’s Gut Bacteria Can Help Detect Early-stage Colorectal Cancer
Analysis of microbiome signatures in plasma for early CRC detection Colorectal cancer (CRC) represents the 3rd leading cause of cancer-related deaths in the United States. Patients diagnosed with distant stage of the disease represent 22% of all CRC cases and have 15% 5-years survival rates, in contrast to 91% 5-years survival rate of patients with localized disease at diagnosis, indicating how ...
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Array-based Methylation Detection Explores the Mysteries of Cancer
Epigenetics is an emerging field of research that focuses on the effects of environmental factors, such as infections, pollutants, stress, and long-term drug exposure, on an individual's genome. Epigenetic changes do not alter the structure of DNA, but do alter the way DNA is modified. Thereby, those changes include DNA methylation, histone modifications and non-coding RNAs. affects gene ...
By CD Genomics
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CD Genomics Perspective: NGS-Based Gene Panels for Cancer Research
IntroductionTumorigenesis involves in many somatic mutations, most of which are random. Generally, hundreds of genes are thought to be associated with oncogenesis progression and have high mutation rates. Digging deeper into the cancer genome can help to understand the molecular mechanisms of tumorigenesis and provide guidance for the prevention, treatment and prognosis strategies. The main ...
By CD Genomics
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Advancing Cancer Treatments with ALZET Osmotic Pumps
The research summarized in this whitepaper provides a number of examples of how ALZET® pumps offer a superior pre-clinical drug dosing option for the delivery of a wide array of anti-cancer agents, including small molecules, immunotherapies, radiotherapies, combination treatments, and novel drug entities. This whitepaper also explores how ALZET® pumps have been used to successfully test ...
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Huateng Pharma Supplies Some Intermediates of CDK4/6 Inhibitors for Treatment of Advanced Breast Cancer
Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. In 2018, it is estimated that 627,000 women died from breast cancer – that is approximately 15% of all cancer deaths among women. While breast cancer rates are higher among women in more developed regions, rates are ...
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How Has the COVID-19 Pandemic Affected Prostate Cancer Care?
#CancelEverything On March 11, 2020, the World Health Organization (WHO) declared the coronavirus 2019 disease (COVID-19) a global pandemic. Its impact left the world uncertain about health, politics and the economy. The first wave caused a major disruption to health services, exacerbating concerns of patient and physician safety and resource availability. On trend with the “cancel ...
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Molecular Glue And Its Application In New Drug Development
In recent years, targeted protein degraders have entered the mainstream of drug development at a very rapid rate. Thalidomide and its derivatives for the treatment of multiple myeloma and other conditions have demonstrated the potential of protein degraders, while ARV-471, an estrogen receptor degrader based on the drug development of thalidomide, is targeted at the early stage of breast cancer ...
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Paclitaxel Injection Market to Grow at Stable CAGR of 12.8% from 2023 to 2032
Global Paclitaxel Injection market document provides actionable industry insights with which sustainable, valuable, and money-spinning business strategies can be created. All the information, facts, and statistics covered in the report lead to actionable ideas, improved decision-making and better-deciding business strategies. With the complete knowledge of business goals and needs to bridge the ...
By insightSLICE
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Water- and wastewater-related disease and infection risks: what is an appropriate value for the maximum tolerable additional burden of disease?
The maximum additional burden of water- and wastewater-related disease of 10_6 disability-adjusted life year (DALY) loss per person per year (pppy), used in the WHO Drinking-water Quality Guidelines and the WHO Guidelines for Wastewater Use in Agriculture, is based on US EPA's acceptance of a 70-year lifetime waterborne cancer risk of 10_5 per person, equivalent to an annual risk of 1.4×10_7 per ...
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Mesothelioma treatment options: patient medical research & pain management
Mesothelioma Treatment Options: Patient Medical Research & Pain Management 1) Keep up an open dialogue with your doctor It is natural to want to understand as much as possible about a disease and its treatments, particularly when the disease is as rare as malignant mesothelioma. The Internet has opened up a wealth of information on mesothelioma, however, it is still important to keep in ...
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Introduction to Protein N-glycosylation
Glycosylation is one of the most important protein post-translational modifications in organisms, occurring in 50%-70% of proteins in cells. It is associated with many diseases as it can affect essential life activities, such as cell recognition, differentiation, adhesion, signal transduction, and immune response. Immune diseases, congenital sugar defects, and dozens of genetic diseases, as well ...
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A Plant Immune Protein May be Expected to Completely Cure Cancer!
Cancer, caused by abnormal cell proliferation, is one of the world's major public health problems. Recently, in a research report entitled "A plant immune protein enables broad antitumor response by rescuing microRNA deficiency" published in Cell, Scientists from institutions such as Peking University have found that a special plant immune protein may achieve a broad spectrum of anti-tumor ...
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Environment and Health
Public concerns, evidence from research and increasing scientific knowledge are all driving widespread discussions on environment and health problems. The issue of environment and health is characterised by multi-causality with different strengths of association. This means that the links between exposures and their health consequences depend on the environmental pollutants and diseases being ...
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Health and Safety in Heavy Industries
Many vapours and gases found in heavy industries pose an explosion risk. For any gas to combust it must reach its lower explosive limit (LELs). Lower explosive limits have been well established for 100s of chemicals and generally vapours from VOCs have relatively low explosion limits. For example, methane and hydrogen have LELs of 50,000 ppm and 40,000 ppm respectively whereas benzene has ...
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Everyone is Sick-Is it the office Air Quality?
Is Office Environment Related To Office Illnesses? Everyone is sick but do they all have the same symptoms? Headaches, flu, itchy skin, sore throats, asthma, COPD, cancer, appendicitis! That’s very important! It’s unlikely if the symptoms are different. If everyone has sore throats or upper respiratory irritation then it may be the building such as low humidity. Usually, the symptoms ...
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Remote Oncology Care: Review of Current Technology and Future Directions
Abstract Cancer patients frequently develop tumor and treatment-related complications, leading to diminished quality of life, shortened survival, and overutilization of emergency department and hospital services. Outpatient oncology treatment has potential to leave cancer patients unmonitored for long periods while at risk of clinical deterioration which has been exaggerated during the COVID19 ...
By Oncodisc
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The Mode of Action of Basic Proteins Involved in Cancer and Alzheimer's Disease Found
These proteins belonging to the HAT family are essential for life because they transport amino acids to the cell membrane. Although members of the family are nearly identical, they selectively transport certain amino acids. This specificity determines their involvement in specific functions, such as cell growth or neuronal function, and consequently in related diseases, such as cancer or ...
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Anti Helicobacter Pylori Formula Shows Initial Results
Helicobacter pylori (Hp) is closely related to the occurrence and development of gastric cancer, peptic ulcer, Hp-related dyspepsia and other diseases. Studies have found that Hp can cause gastric microbial disorders, change the microbial diversity and community structure in the stomach, and cause precancerous lesions. The public health community has made great efforts to eradicate Hp for a long ...
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