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Carcinoma Scc Articles & Analysis

1 articles found

Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma

Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma

To discover novel druggable targets for cancers carrying co-mutations in Ras and p53, we performed arrayed, kinome focused siRNA and oncology drug phenotypic screening utilizing a set of syngeneic Ras mutant squamous cell carcinoma (SCC) cell lines that also carried co-mutations in selected p53 pathway genes. These cell lines were derived from ...

BySEngine Precision Medicine

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