cardiovascular Articles
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Temperature and direct effects on population health in Brisbane, 1986–1995
To assess the impact of weather on human mortality, particularly among elderly people and people with diseases, the authors conducted an ecological study in Brisbane, Australia. Correlation and autoregressive integrated moving average (ARIMA) regression analyses assessed the relationship between weather and mortality in the general population and the elderly population (65 years of age and older) ...
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Cardiovascular metrics and transepidermal water loss in a high heat risk environment
Heat stress is currently primarily classified by environmental factors and not physiological factors. It is already known that certain cardiovascular metrics such as heart rate, stroke volume, blood pressure and vascular compliance undergo changes as the body traverses the different classifications of heat stress from heat oedema to heat stroke. However, there is no specific metric that provides ...
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Hospital admissions and air mass types in Athens, Greece
We examined the effects of air mass types on hospital admissions due to respiratory and cardiovascular diseases, in Athens, Greece for 1992-2000. Health data were analysed according to the sex and age group of the patients admitted to the hospital. It was found that increased hospital admissions were associated with very poor ventilation for the Athens Basin and moisture environment. Hospital ...
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Toxic effects of single-walled carbon nanotubes on the cardiovascular system: state of art
Engineered single-walled carbon nanotubes are a new class of synthetic compounds in the nanometric scale, with unusual chemical and physical characteristics, which make them a very promising material in different industrial and biomedical fields. Their use is predicted to increase exponentially in the next few years. Given their similarity to the ultrafine component of air pollution, there is ...
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Gene Expression Visualisation
Mosaic is the data management and visualisation solution being used by the Cardiovascular Development Data Resource Center (CDDRC), working with multiple omics data types for a variety of model organisms as well as human. We recently put out a blog post on the CDDRC website highlighting how data visualisation in Mosaic was able to help researchers better understand trends in their data. This ...
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Structural and functional changes in cardiovascular system at arterial hypertension in persons exposed to ionising radiation
The purposes of this research were: (1) to carry out the comparative evaluation of indices of the morphofunctional condition of the cardiovascular system (CVS) in patients with arterial hypertension (AH) exposed to ionizing radiation, taking into account the occurrence of peripheral arterial atherosclerosis and the spread of traditional risk factors of cardiovascular diseases (CVD); (2) to ...
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Ultromics at the American Society of Echocardiography’s 2023 Scientific Sessions
Ultromics will be sharing its groundbreaking AI research and innovation at the American Society of Echocardiography’s annual Scientific Sessions. ASE’s Foundations and the Future of Cardiovascular Ultrasound sessions bring together echo professionals and enthusiasts from across forty-five countries with a selection of networking events, seminars, and workshops from the top minds in ...
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Comparison of Quantity of Coronary Atherosclerotic Plaques Detected by Computed Tomography Versus Angiography
Abstract Numerous clinical studies using coronary computed tomography angiography (CTA) and conventional invasive coronary angiography (ICA) confirmed the strong relation between atherosclerotic disease burden and risk of adverse events. Few studies have compared coronary CTA and ICA regarding semiquantitative plaque burden measurements, reproducibility, and cardiovascular risk assessment. ...
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UK Imaging Diabetes Study Seeing Diabetes Clearly - Case Study
Prospective observational cohort study with clinical outcomes data collection. Recruiting adult patients with type 2 diabetes (T2DM) and diabetic retinopathy (DR), who lack history of cardiovascular ...
By Perspectum
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Results Published from FIH Study of Thrombolex’s Bashir Endovascular Catheter
February 9, 2021—Findings from the first-in-human (FIH) study assessing the safety and feasibility of the Bashir endovascular catheter (BEC; Thrombolex, Inc.) for the treatment of acute intermediate-risk pulmonary embolism (PE) were published by Akhilesh K. Sista, MD, et al in Circulation: Cardiovascular Intervention (2021;14). The BEC is a pharmacomechanical device designed to enhance ...
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Willingness to Pay to Reduce Mortality Risks: Evidence from a Three-Country Contingent Valuation Study
Valuing a change in the risk of death is a key input into the calculation of the benefits of environmental policies that save lives. Typically such risks are monetized using the Value of a Statistical Life (VSL). Since the majority of the lives saved by environmental policies are those of older persons, there has been much recent debate about whether the VSL should be lower for the elderly to ...
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Blood pressure–lowering effect of orally ingested nitrite is abolished by a proton pump inhibitor
Abstract Inorganic nitrate and nitrite from dietary and endogenous sources are metabolized to NO and other bioactive nitrogen oxides that affect blood pressure. The mechanisms for nitrite bioactivation are unclear, but recent studies in rodents suggest that gastric acidity may influence the systemic effects of this anion. In a randomized, double-blind, placebo-controlled crossover study, we ...
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Will Metformin Be Replaced By SGLT-2 Inhibitors
Metformin is a classic first-line hypoglycemic agent for patients with type 2 diabetes, and is an essential drug in combination regimenes. However, as the evidence is updated, the idea of drug selection for first-line treatment is changing. GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple ...
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Copper in human health
Copper is an essential mineral for human health and at the same time can be toxic, depending upon the amounts ingested. Copper is associated with bone health, immune function and increased frequency of infections, cardiovascular risk and alterations in cholesterol metabolism. Its metabolism is tightly intertwined with other microminerals and its deficiency is known to impair iron mobilisation, ...
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Cardiovascular Consequences of Acute Kidney Injury
Annotations Acute kidney injury (AKI) is recognized as a potential risk factor for future cardiovascular events, especially heart failure. Up to 60% of patients with severe AKI who are admitted to an intensive care unit (ICU) die; the long-term risk of death associated with AKI is also increased. Preclinical models and biomarkers have identified several likely pathways, apparently involving ...
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What Is a Good Heart Rate Variability? : Modern Health and Fitness
Defining a good heart rate variability has always been a question within the fitness community. Different lifestyles can dictate a person’s overall cardiovascular health which is why the answer typically varies from person to person. Thankfully, with modern advancements in technology, it’s now much easier to track and monitor these types of health information. We can now check not ...
By Sky Labs
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3 tips to improve cardiovascular health
Cardiovascular diseases (CVDs) cause 17 million deaths globally every year, making it the leading cause of death around the world. The cardiovascular system—which includes your heart and blood vessels—distributes oxygen through the body and removes waste. Every cell in the body depends on this process to run smoothly. Your cardiovascular system plays a key role in your overall ...
By Evidation
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Building effective institutional frameworks to support pharmacogenetic research: an international empirical analysis
As science unravels the genetic basis of disease, the opportunities offered by pharmacogenetics and pharmacogenomics (PGx) for future healthcare become more and more apparent. The objective of this paper is to analyse the current state of PGx research and explore future strategies for more efficient research projects and supportive infrastructures. Based on internet searches and an online survey ...
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Emerging therapy for HFpEF: SGLT2 inhibitors
Recent clinical trials investigating sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with heart failure with preserved ejection fraction (HFpEF). HFpEF is a complex disease which accounts for more than half of all heart failure (HF) hospital admissions and is an increasing disease burden. [1] The prevalence of HFpEF is ...
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Ensuring compliance - Coregas case study
Customer: Coregas Application: Gas Background: Coregas is the largest Australian owned industrial, medical and specialty gas company. Their gases range from common gases such as oxygen and nitrogen to the rarest of gases like krypton. Coregas provide gases to the medical sector of the highest levels of purity, consistency and are fully compliant with all relevant Australian government ...
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