Cell Biology Cell Therapy Articles & Analysis: This-Year
12 articles found
In modern biopharmaceutical manufacturing, downstream processing development has become one of the most critical and resource-intensive stages. While upstream cell culture or fermentation focuses on producing the target biomolecule, downstream steps transform crude harvests into highly purified and stable therapeutic products. For biologics such as monoclonal antibodies, recombinant proteins, and ...
The BCL2 gene, short for B-cell lymphoma 2, is a critical regulator of apoptosis, or programmed cell death. ...
By administering recombinant chemokines, scientists can redirect immune cells to the tumor microenvironment, potentially enhancing the efficacy of checkpoint inhibitors or CAR-T cell therapies. ...
Cancer treatment has witnessed transformative advancements over the past few decades, notably with the emergence of CAR-T (Chimeric Antigen Receptor T-cell) therapy. This revolutionary therapy harnesses the body's immune system by genetically engineering T-cells to target and destroy cancer cells. Among the pioneering companies at the forefront of this innovation is Alfa Cytology, renowned for ...
Unlocking the Power of Organoids Organoids are three-dimensional structures that replicate the functions of actual organs within the body. They develop from progenitor cells, which researchers obtain either from embryonic tissues or pluripotent stem cells (PSCs). ...
Regenerative Potential of Podocytes One of the intriguing aspects of podocyte biology is their limited ability to regenerate. Unlike other cell types in the body, podocytes do not readily proliferate in response to injury. ...
Alfa Cytology employs state-of-the-art techniques including isolation, culture, engineering, expansion, and characterization of immune cells and stem cells to develop novel cell therapies. These innovative solutions are grounded in a comprehensive understanding of tumor biology and immune system dynamics, ...
Both concepts encapsulate the complexity of cellular processes and open new avenues for targeted therapies. What is Synthetic Lethality? Synthetic lethality occurs when the simultaneous disruption of two genes leads to cell death, whereas the disruption of either gene alone does not affect cell survival. ...
Immuno-oncology is an innovative field that utilizes the body’s immune system to combat cancer. By harnessing the natural capabilities of the immune system, immuno-oncology services are revolutionizing the way we approach cancer treatment, offering novel therapies that are changing the prognosis for many patients. Understanding Immuno-Oncology Immuno-oncology focuses on the interaction ...
These findings could improve our understanding of neurological disorders such as autism and epilepsy. 3. Protein Mapping in Cell Cycle Phases A 2024 study mapped out thousands of proteins involved in cell division, providing a molecular blueprint for developing more targeted cancer therapies. Implications for Cancer Treatment Since ...
This initiative signifies a major leap forward in the development of more effective cancer therapies, aiming to boost both precision and versatility within treatment paradigms. As cancer treatment methodologies continue to evolve, there is an escalating demand for innovative and personalized approaches. Traditional therapies often lack the specificity needed to ...
Leukemia, a malignant disorder of the blood and bone marrow, poses significant challenges to both patients and healthcare providers. Traditional treatments, including chemotherapy and radiation, while effective for some, often come with severe side effects and varied success rates. Enter immunotherapy - a groundbreaking approach that is not only redefining leukemia treatment but also offering ...