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Cholesterol Ldl Articles & Analysis

4 articles found

Regulation of Lipid Metabolism in the Intestinal Flora

Regulation of Lipid Metabolism in the Intestinal Flora

In addition, supplementation of conventionally reared mice with specific bacterial strains resulted in increased body weight, elevated LDL and cholesterol levels, and altered expression of some genes involved in lipid transport. ...

ByCreative Proteomics


Abstract 9761: Novel Modulators of Low Density Lipoprotein Receptor Metabolism

Abstract 9761: Novel Modulators of Low Density Lipoprotein Receptor Metabolism

Abstract Intervention with drugs to reduce Low Density Lipoprotein-cholesterol (LDL-C) has proven to decrease the risk of subsequent cardiovascular events, including mortality. Our goal is to develop novel, small molecule, LDL-C lowering drugs by targeting the Low Density Lipoprotein Receptor (LDLR) degradation pathway, which is modulated by ...

ByShifa Biomedical Corporation


Abstract 10306: Identification and Characterization of Orally Bioavailable Small Molecule Protease Proprotein Convertase Subtilisin-like Kexin Type 9 Inhibitors (Best of Basic Science Abstract)

Abstract 10306: Identification and Characterization of Orally Bioavailable Small Molecule Protease Proprotein Convertase Subtilisin-like Kexin Type 9 Inhibitors (Best of Basic Science Abstract)

Abstract Intervention with drugs to reduce low density lipoprotein-cholesterol (LDL-C) has proven to decrease mortality and morbidity. Here, we report the development of small molecules that lower LDL-C by targeting the LDL-receptor (LDLR) degradation pathway, which is modulated by the protease proprotein convertase ...

ByShifa Biomedical Corporation


Effects of tobacco (smoking and snuffing) in type 2 diabetic patients

Effects of tobacco (smoking and snuffing) in type 2 diabetic patients

Similarly glycosylated hemoglobin level of smoking, snuff addicted diabetic group was also non–significantly higher but that of both addicted group was non–significantly lower with p–value > 0.05. Similarly the cholesterol, triglycerides, HDL–cholesterol, LDL–cholesterol levels of smoking, snuff and both addicted diabetic groups ...

ByInderscience Publishers

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