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Chronic Diseases Articles & Analysis
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In soft tissues like arteries, unregulated hydroxyapatite accumulation leads to vascular calcification, a pathological condition associated with atherosclerosis, diabetes, chronic kidney disease (CKD), and aging. Studies in MGP-knockout mice have shown extensive arterial calcification and premature death, underscoring the importance of this protein in ...
Key pathologies associated with excessive ELANE activity include: l Chronic obstructive pulmonary disease (COPD): ELANE-mediated degradation of lung elastin contributes to alveolar destruction and emphysema. ...
Smokers significantly increase the risk of developing Chronic Obstructive Pulmonary Disease (COPD) and lung cancer, as well as heart disease. ...
Why Is NAD/NADH Analysis Important? Metabolic Health and Disease Research Alterations in NAD/NADH levels are associated with a wide range of diseases, including cancer, diabetes, neurodegenerative disorders (e.g., Alzheimer’s and Parkinson’s), and mitochondrial diseases. ...
It has been reported to be effective in treating chronic pain conditions, including fibromyalgia and chronic back pain. ...
Elastase in Pathological Conditions One of the most well-studied conditions involving elastase is emphysema, a form of chronic obstructive pulmonary disease (COPD). In emphysema, excessive activity of neutrophil elastase results in the degradation of elastin in the lung's alveolar walls, leading to impaired lung function and reduced elasticity. ...
This test is commonly used to monitor a patient's immune response to biological agents or other drugs, especially in the treatment of chronic diseases such as autoimmune diseases, certain cancers, and inflammatory diseases. ...
MMPs are involved in pathological processes such as hypertension, eclampsia, vascular inflammation, atherosclerosis, coronary syndromes and myocardial infarction, cerebral ischemia and ischemic stroke, peripheral arterial disease, aneurysms, chronic venous disease, etc. MMPs can be used as biomarkers and potential therapeutic targets for certain ...
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. ...
Evaluating the stress related effects of various restraint methods in rodents Any restraining device used in an inhalation exposure set-up will be, by definition, restricting the subject’s ability to move. For nose-only inhalation set-ups, typical restraints are rigid, fully enclosed and include a metal or acrylic plunger forcing the subject forward and preventing the subject from ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. ...
Treatment of Cystic Fibrosis CF is a chronic and progressive disease with no known cure, but there are several treatments available that can help manage the symptoms and improve the quality of life for people with the disease. ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. ...
Diabetes is a chronic disease that affects more than 540 million people worldwide and is one of the leading causes of death and disability worldwide. ...
GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple guidelines as appropriate initial treatment for type 2 diabetes patients with atherosclerotic cardiovascular disease (ASCVD) or those at high risk for ASCVD, heart failure and/or chronic kidney ...
RPM technology has been particularly helpful in managing chronic conditions like diabetes, where patients can monitor their blood sugar levels and share this data with their healthcare providers. ...
Application in medical research Etiology research. There are lots of untreated diseases with unknown etiologies, which are called idiopathic diseases in clinics. ...
Did you know that almost 36 million people in the EU live with a rare disease and the number goes up to 350 million worldwide? These diseases are an important cause of chronic illness, disability, and premature death in children as well as adults. A rare disease is any disease that affects a very small ...
Medical History Jane is a 40-year-old, married mother of two teenage boys. She teaches at the local elementary school and has been in good health for most of her life. She has no surgical history. Her most severe ailment up to this point has been the flu at age 27. Her students are first-graders; they are often difficult to control. She also experiences the normal stresses of raising ...
Medical History A 55-year-old white male has degenerative arthritis of the knees. 10 months ago, the patient underwent total knee replacement on the left knee without complication. The surgical incisions had closed without signs of surgical site infection. At the time, he made a good recovery. He is fully functional and fully independent. Patient is a chain smoker with a wife and two children. He ...