clinical practice Articles
-
A generic approach to computer-based Clinical Practice Guideline management using the ECA Rule paradigm and active databases
The increasing demand for reduced cost and improved quality of service in healthcare has prompted the call for better management of medical knowledge. The main emphasis has been on knowledge that is acquired through experience and medical research and then formalised into Clinical Practice Guidelines (CPGs). This paper presents a generic approach to CPG information and knowledge management that ...
-
An automatic dose dispenser for microtablets--a new concept for individual dosage of drugs in tablet form
Abstract A new concept for individualising the dosage of drugs in solid form is presented. The principle is based on the use of standardised units (microtablets), each containing a subtherapeutic amount of the active ingredient. The required dose is fine-tuned by counting out a specific number of these units. The microtablets are counted electronically from the attached cassette by the ...
By Sensidose AB
-
Clin.iobio Paper Published in Special Issue on Precision Medicine in Clinical Practice
Having recently published a paper on gene.iobio, we are excited to announce a publication describing the clin.iobio tool as part of the Journal of Personalized Medicine's Special Issue on Precision Medicine in Clinical Practice. Clin.iobio has been developed by the iobio team in Prof. Gabor Marth's lab at the University of Utah, with collaboration from Frameshift. Clin.iobio has been built to ...
-
Mechanism of action and therapeutic efficacy of the biotechnology-derived immunostimulating extract OM-85 in respiratory tract infections
The burden of Respiratory Tract Infections (RTIs) in children and adults is very high, especially in developing countries. At least 1.9 million children throughout the world died from acute RTIs in 2000, 70% of them in Africa and Southeast Asia. As causative therapies of these frequently recurring infections have substantial limits, preventive measures deserve priority. Among these, non-specific ...
-
Parkinson`s disease therapy: tailoring choices for early and late disease, young and old patients
Abstract Advances in the understanding of basal ganglia circuitry and its altered function in disease states such as Parkinson's disease (PD), coupled with new insights into the mechanisms of cell death and new findings from therapeutic clinical trials, are being translated into clinical practice. Although levodopa (L-Dopa) remains the most effective drug in the symptomatic treatment of PD, ...
By Sensidose AB
-
Thermoacoustic Imaging: A Novel Method for Quantifying Fat in NAFLD
Abdominal ultrasound imaging is a widely available, low cost, point of care procedure that is used in daily clinical practice as the first-line examination to identify liver steatosis in patients with increased liver blood exams or suspected NAFLD. Despite the broad use of abdominal ultrasound imaging, its sensitivity among morbidly obese patients is low, and it may miss the diagnosis when the ...
-
The use of Episcissors-60 to reduce the rate of Obstetric Anal Sphincter Injuries: A systematic review
Abstract Objectives: The aim of this systematic review is to evaluate the effect of Episcissors-60, which were designed to improve the accuracy of episiotomies, on the rate of Obstetric Anal Sphincter Injuries. Study design: This review is registered with the International Prospective Register of Systematic Reviews (PROSPERO) database (CRD42018094935). A literature search of the PubMed, ...
-
Decreasing Benign Breast Ultrasound Biopsies: Prospective Use of AI Decision Support
After implementation of AI decision support, the benign biopsy rate decreased from 71.79% to 59.2% while the overall biopsy rate stayed constant. PPV3 increased from 28.2% to 40.8%. Objective To examine the affect of prospective AI decision support (Koios DS Breast) use on breast ultrasound biopsy performance metrics. Materials and Methods Non-identifiable HIPAA compliant data collected ...
-
Improving Clinical Practice Can Benefit Staff and Patients - Case Study
Background A 16 y/o male with a history of irritable bowel disease presents to the Emergency Department vomiting blood. He has an ostomy in place. His initial vital signs were BP 82/59, HR 160, SI 1.95. He was ill-appearing, with skin gray and ashen. The staff placed a 20-gauge peripheral IV and infused a 1-liter NS bolus using the LifeFlow PLUS and the QinFlow Warrior blood and fluid warmer. ...
By 410 Medical
-
Immunostimulants in the prevention of respiratory infections
Immunomodulation promises to be an effective prophylactic and therapeutic modality for chronic and recurrent respiratory infections. As opposed to vaccines, the term Immunostimulant (IS) refers to a compound that produces a state of non-specific immunity. Most IS are oral formulations of bacterial lysates that have been used in clinical practice for decades. One of the main obstacles in the ...
-
Diamond coated microtools for machining compact bone
The structure of compact bone is heterogeneous and as such, is difficult to shape by cutting tools during clinical surgical practices. The structure of bone can have a devastating effect on the performance of the cutting tool unless it is coated with a thin solid film that is wear resistant. The paper investigates the use of diamond coated cutting tools to prepare bone for prosthetic implants and ...
-
Landmark Study Shows a 0% Blood Culture Contamination Rate is Achievable with Steripath
As a professor in infectious disease and microbiology, epidemiologist, and Medical Director of Infection Prevention and Control at Stanford Health Care, Dr. Lucy S. Tompkins was skeptical that a 0% blood culture contamination rate could be achieved, especially in a major academic medical center. Study Results In an oral abstract of the Steripath Gen2 Initial Specimen Diversion Device® ...
-
Treatment for Dentin Hypersensitivity using 980nm
Do you suddenly find that your teeth become very fragile, you will start to have a toothache when you drink cold water, eat ice-cream, and even when you brush your teeth? This is the symptom of tooth sensitivity. Compared to conventional desensitizing topical agents, the laser treatment leads to rapid results with less application time and more quickly for the patient. The discomfort of patients ...
By PIOON
-
FIGO good clinical practice paper: management of the second stage of labor
Abstract This good clinical practice paper provides an overview of the current evidence around second stage care, highlighting the challenges and the importance of maintaining high-quality, safe, and respectful care in all settings. It includes a series of recommendations based on best available evidence regarding length of second stage, judicious use of episiotomy, and the importance of ...
-
Dermal absorption of chlorpyrifos in human volunteers
Objective: The methods and results are described of a study on the dermal absorption of chlorpyrifos (CPF) in humans established via urinary excretion of the metabolite 3,5,6-trichloro-2-pyridinol (TCP). Methods: Two dermal, single, doses of CPF were applied in two study groups (A and B) each comprising three apparently healthy male volunteers who gave their written informed consent. The clinical ...
-
Summary of new EU Clinical Trial Regulation
The changes the regulation brings companies need to already be reviewing their current processes, systems and supporting infrastructure for clinical trial applications and operations. They need to do so in every changing regulatory environment where Clinical Trial and related data is being ever more scrutinized. This paper provides a synopsis of the new regulation Insights on timing The ...
By DDi LLC
-
Significance of Diagnostic Enzyme Detection
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...
-
Application of Enzyme Detection in Clinical Diagnosis
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...
-
What is Urine Flow Rate Test?
What is urine flow rate test? You may be unfamiliar with the term urine flow rate or urinary flow rate, which is a common medical term in urology. Put it simply, the rate of urine flow measures how fast urine flows, how much it flows out, and how long it takes. It is expressed in ml/s. Urine flow rate test is done mainly when the following symptoms appear: bladder residual urine increase ...
-
API - Oseltamivir Phosphate
Introduction Oseltamivir phosphate is a white or almost white crystalline powder with the chemical name ethyl(3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-cyclohex-1-ene-1-carboxylate phosphate. It is an influenza viral neuraminidase inhibitor used in the prevention and treatment of influenza. Application in the treatment of influenza Introduction of influenza Influenza, also called flu or ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you