clinical research Articles
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Protein Quantification Techniques and Their Application in Clinical Research
Representing the expression, post-translational modification, and protein-protein interaction for certain cells, tissues, or organs, proteomics has become an increasingly important means to understand the molecular mechanism and signal transduction of human disease and cancer. Protein levels in the body are in a steady state of equilibrium. Accumulation of proteins usually leads to qualitative ...
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Nanostics is Developing and Validating a Simple Blood Test to Predict Severity of COVID-19 Disease in SARS-CoV-2 Positive Patients
Edmonton, Alberta - Nanostics Inc., a diagnostic healthcare company that focuses on developing tests to determine a patient's disease risk, announced today plans to develop and validate ClarityDX COVID-19; a simple blood test to predict the severity of COVID-19 disease in patients. Nanostics, in collaboration with the Canadian BioSample Repository (CBSR) at the University of Alberta and Century ...
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Research paper related to ResPower Respiratory Neuromuscular Stimulator was accepted by ERS International Congress
Research paper related to ResPower Respiratory Neuromuscular Stimulator was accepted by ERS International Congress Respiratory Neuromuscular Stimulator was used in clinical research in Beijing Chaoyang Hospital affiliated to Capital Medical University, the First Hospital of Hebei Medical University and Tianjin Chest Hospital. Subsequently, the articles were submitted one after another and were ...
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How Clinion Helped PHFI Modernize its Data Management Processes
Meeting the shortfall of health professionals is imperative to a sustained and holistic response to public health concerns of any country. The Public Health Foundation of India (PHFI), a public and private initiative, addresses these concerns by strengthening training, research and policy developments to create a healthier India. PHFI has partnered with Clinion to digitise its legacy data ...
By Clinion
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Phase I STTR award
Gene.iobio is a popular variant analysis tool developed at the University of Utah in the laboratory of Professor Gabor Marth. With an average of 15,000 weekly page views, gene.iobio is used by academic variant analysts, clinical researchers, and is available to customers of a direct to consumer genomics company. In order to continue delivering a high-quality experience to all users, we have ...
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Digital Endpoints in Clinical Trials for Neurology: Benefits and Impediments to Adoption
In addition to the pandemic, the digitization of healthcare is rapidly shifting clinical trials from analog to hybrid or fully decentralized clinical trials, catalyzing the development and implementation of digital health technologies to support clinical research. Digital endpoints not only support the decentralization of clinical trials but also provide a means to collect more sensitive, ...
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Application of Flow Cytometry in the Pharmaceutical Industry
Flow cytometry (FC) is an important tool for analyzing complex pathways and responses of single cells, which can track cell phenotypes and functions in multiple dimensions. It is also increasingly applied in drug development. FC not only can detect intracellular and extracellular components, but also detect soluble analytes in serum or plasma samples, such as cytokines, drug complexes, or ...
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Bridging Clinical Research to Real-World Patient Care Through Predictive Analytics
The ability to predict how a clinical trial participant will adhere to their treatment, and even respond to that treatment, has great promise to advance patient-centric clinical research. But, as we look to understand the impact a drug has on patients’ everyday health outside of a research environment, what happens to these unique, predictive findings around dosing and outcomes once a drug ...
By AiCure
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Robust cybersecurity protection for hospitals requires a combination of education and technology tools
Across industries, the Internet of Things (IoT) is driving significant investment in projects that integrate smart devices, big data, analytics, and other digitization-related tools. Healthcare institutions are no exception. Hospitals benefit from this advanced connectivity through increased efficiencies, lower costs, and better patient care. As more building infrastructure gets connected; ...
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Reversing the Psychiatric Effects of Neurodevelopmental Cannabinoid Exposure: Exploring Pharmacotherapeutic Interventions for Symptom Improvement
Abstract: Neurodevelopmental exposure to psychoactive compounds in cannabis, specifically THC, is associated with a variety of long-term psychopathological outcomes. This increased risk includes a higher prevalence of schizophrenia, mood and anxiety disorders, and cognitive impairments. Clinical and pre-clinical research continues to identify a wide array of underlying neuropathophysiological ...
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What makes decentralisation the future of clinical trials?
With the emergence of COVID-19, Decentralisation of Clinical Trials became necessary to comply with social distancing requirements while carrying out clinical research. Over the past few years, the clinical trial landscape has shifted its focus to patient-centric practices to promote patient engagement. But now as the pandemic is long gone, it is time to reflect on how DCT studies are genuinely ...
By Clinion
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The Clinical Data Interchange Standards Consortium welcomes Lifebit as a partner
What is the Clinical Data Interchange Standards Consortium? The Clinical Data Interchange Standards Consortium (CDISC) is a global, not-for-profit organisation that develops data standards across all the healthcare sector. Founded in 1997, over the last 20+ years CDISC has provided guidance on the transformation of clinical data from incompatible into interoperable formats so that it is usable, ...
By Lifebit
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Blazing the trail from stem cell research to regenerative medicine
Stem cell research holds promise for applications in regenerative medicine. However many questions remain. For example, will it be possible to patent therapeutic products in this area? Will the necessary investment be forthcoming? In addition there are still many technical problems to be solved. Technical solutions may involve the use of human embryos and this has created barriers to the use of ...
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Functional Respiratory Imaging Can Predict the Course of Covid-19
Functional Respiratory Imaging (FRI) quantifies and visualizes the distribution of blood vessels in the lungs in great detail. This simple model, which combines the results of the imaging with the patient’s age, can accurately predict the risk of dying and the necessity for ventilation. Clinical research conducted has revealed that inflammation of the endothelium and microangiopathy occur ...
By Fluidda
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Clinical Research On-Demand: How the University of Washington’s Theberge Lab is Using Tasso to Study Unpredictable Events in Real Time - Case Study
Many important research questions cannot be studied under controlled circumstances. Events like natural disasters or disease exposure often occur without warning and prevent in-person clinic visits, making timely observation difficult without a flexible approach. At the University of Washington, researchers are partnering with Tasso to study these scenarios by deploying on-demand remote ...
By Tasso, Inc.
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Bio-tech firm recruiting Yukon men for trial, Prostate cancer group says it could save lives
The Yukon chapter of Ride For Dad says a new blood test developed by an Alberta-based company could save the lives of men at risk of prostate cancer. (iStock/Getty Images) A bio-technology company based in Alberta is testing a new process that could result in fewer Yukon men travelling out of territory for prostate cancer biopsies. Private research company Nanostics Inc. and the University of ...
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Mold and Chronic Sinusitis - The two are linked says mayo clinic
Wondering Whether Mold and Chronic Sinusitis are Linked? Do you suffer from frequent sinus headaches, congestion, and runny nose? Have you taken enough cold and allergy medication to qualify for “frequent flier” awards? You may not have a persistent cold or allergies. Researchers at the Mayo Clinic have discovered what may be the real cause of most chronic sinus conditions: MOLD! ...
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Big, Small & Wide: Combining Old and New Data Approaches to Advance Precision Medicine
For decades, data scientists and AI developers have typically followed the belief that “bigger is better” – the bigger the data set, the more analytical freedoms one has, and the more insights one gains. The AI industry still heavily relies on big data analytics, and for good reason – we need to feed AI large amounts of high quality, diverse data to ensure it works ...
By AiCure
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InfraScan Inc. Announces Publication of the Largest Study to date for TBI Diagnosis Utilizing NIRD
InfraScan, a medical device firm specializing in traumatic brain injury diagnostic products, announced the publication of the largest U.S. study to date using a near-infrared device (NIRD) to detect bleeds resulting from Traumatic Brain Injuries (TBI). This independent study was published in the Journal of Neurotrauma on 2 Aug 2022. https://doi.org/10.1089/neu.2021.0342. “We wish to thank ...
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The Toxicity Atlas - One year later
It’s been about a year since I started my PhD project named The Toxicity Atlas. In this four-year project, I’m collaborating with researchers from Amsterdam UMC and my colleagues at Medstone to find better treatment options for patients with brain cancer. Let me tell you more about my results so far. Information databases Developing new drugs costs a lot of money and a lot of ...
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