clinical test Articles
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Omega 3 and Heart Diseases
In a clinical test done on 11,000 patients, those who followed a diet rich in omega 3 fatty acids were able to reduce the risk of sudden death by about 40%. Both the American Heart Association and other associations have made recommendations for the inclusion of omega 3 in our diet, which can be achieved by ingesting fish oil capsules, fish rich in fatty acids such as sardines, anchovies and ...
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Nanogenomics for medicine: emerging strategies to overcome bottlenecks in siRNA-based therapy of human diseases
Silencing of gene expression by siRNA holds a promise both for a drug target discovery and as a therapy. Major bottlenecks of siRNA technology include 'off-target' silencing effects and problems with siRNA degradation before delivery. We propose a two-fold approach aimed at curtailing described shortcomings. First, before pre-clinical tests each siRNA shall be matched to comprehensive redundancy ...
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Assessing antibiotic resistance of microorganisms in sanitary sewage
The release of antimicrobial substances into surface waters is of growing concern due to direct toxic effects on all trophic levels and the promotion of antibiotic resistance through sub-inhibitory concentration levels. This study showcases (1) the variation of antibiotics in sanitary sewage depending on different timescales and (2) a method to assess the antibiotic resistance based on an ...
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Metafora and collaborators publishes a paper in Annals of Neurology
METAFORA is proud to announce that its first publication related to the use of its technology to diagnose a rare metabolic disease rapidly and efficientely has been accepted for publication in the reference journal, Annals of Neurology. The test is being commercialized under the name METAglut1 and was recently CE marked. It is available in France through the CERBA network of clinical testing ...
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Nuritas creates “world’s first” clinically tested anti-aging peptide discovered by AI
Nuritas has discovered two ingredients called PeptiYouth and PeptiStrong that can be integrated into everyday products, including serums and supplements, to fight the effects of aging on skin and muscles. The company names stem cell aging as a growing focus for start-ups. It also says one of consumers’ most significant concerns is combating the adverse effects of aging. Nuritas uses its ...
By Nuritas Ltd.
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Expanded and Activated Natural Killer Cells for Immunotherapy of Hepatocellular Carcinoma
Abstract Viral infection of the liver is a major risk factor for hepatocellular carcinoma (HCC). Natural killer (NK) cells recognize virally infected and oncogenically transformed cells, suggesting a therapeutic role for NK-cell infusions in HCC. Using the K562-mb15-41BBL cell line as a stimulus, we obtained large numbers of activated NK cells from the peripheral blood of healthy donors. ...
By Nkarta, Inc.
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What’s new in Balance Software ´21 version?
A completely redesigned version, PhysioSensing Balance Software´21 was already released, after a long journey of new developments and software improvements. PhysioSensing Balance Software´21, after 10 years of development and experience, is now a powerful balance software analysis tool. We are updating it to all our clients. In this version, you can find: A newdesign, that allows ...
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What Clinical Trial Speed Factors Can Sponsors Actually Control?
When promising drug candidates are identified for further investigation in clinical trials, sponsor companies are usually optimistic about outcomes. But there are times, when after years of sunk effort and resources, clinical trials fail to bring a viable drug to market. Frequently, a drug fails for safety or efficacy reasons that are beyond a sponsor’s control. However, to some degree, ...
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Accelerating stem cell knowledge into regenerative medicine by OUH-CELL-BENCH
One major challenge for implementing stem cell treatment in the clinics, is the interdisciplinary work required by stem cell biologists and medical doctors as well as the state-of-the-art equipment needed at public hospitals to successfully translate the basic stem cell knowledge into clinical products. Our facility directly serves to speed up the development cell therapeutics, by establishing an ...
By Baker
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Brushing Your Allergies Away
Derek Lacarrubba was allergic to New York City. Lacarrubba, 31, got stuffed up around cats, dogs, three kinds of dust mites and several varieties of native New Yorkers - trees, that is. He couldn't sleep. He had trouble going to the gym. And as an attorney, he was too busy to commit to the years-long treatments doctors typically recommend: weekly shots at the doctor's office or holding liquid ...
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Continuous mixing systems for the production of pharmaceutical tablets and granulates
The Process Analytical Technology initiative demands the implementation of in-process monitoring systems and controls along with the mixing process. Gericke has developed continuous mixing and metering systems that meet the stipulated accuracy and the highest hygienic requirements. Own testing and model calculations demonstrate that their efficiency is determined not only by ...
By Gericke AG
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Arterial reconstruction with human bioengineered acellular blood vessels in patients with peripheral arterial disease
Abstract Objective: Vascular conduit is essential for arterial reconstruction for a number of conditions, including trauma and atherosclerotic occlusive disease. We have developed a tissue-engineered human acellular vessel (HAV) that can be manufactured, stored on site at hospitals, and be immediately available for arterial vascular reconstruction. Although the HAV is acellular when implanted, ...
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How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
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How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
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AXIM Biotech chooses the iPeak for the Dry Eye Disease Diagnostics
Founded in 2014 in California, AXIM® Biotechnologies, Inc. is a vertically integrated research and development company focused on improving the landscape for diagnosis of ophthalmological conditions such as Dry Eye Disease (DED) through rapid diagnostic tests. Additionally, it owns IP and has conducted research on SARS-CoV-2 (COVID-19) rapid neutralizing antibody tests to detect ...
By IUL S.A.
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Gene Therapy for Cystic Fibrosis
What is cystic fibrosis? Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that regulates chloride ions transport across cell membranes. These mutations cause the CFTR protein to be either absent or not function ...
By Protheragen
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A new article in JAMA reports self-blood glucose monitoring for type 2 diabetes is not necessary
According to the Centre for Disease Control and Prevention, CDC report 2017; 30.3 million Americans – 9.4 percent of the U.S. population had diabetes in 2015. Home blood glucose monitoring is useful to determine the daily adjustments in treatment or insulin intake. It is advised to follow doctor's recommendations about how often to test the glucose levels. According to an article published ...
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Bear-Moon Clinical Case Study
The BEAR Implant is the first medical advancement to enable your body to heal its own torn anterior cruciate ligament (ACL). That’s a big deal, because until now your ACL would have been replaced with either another tendon from your body or a tendon from a deceased donor. The BEAR Implant is different because it works with your own blood to heal the torn ends of your ACL back ...
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Everything You Want to Know About Horseradish Peroxidase
Peroxidase, usually derived from horseradish, is a common enzyme used in clinical testing reagents. It is widely used not only in several biochemical assays but also in immunoassay (ELISA) kits. As a key component of the color development system of several kits, peroxidase has an important impact on the quality of the kits. Horseradish peroxidase (HRP) is the most commonly used enzyme because ...
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Nanostics Re-Opens ClarityDX Prostate Clinical Study with New US Recruitment Site
Summary Nanostics' clinical validation study for ClarityDX Prostate, a liquid biopsy test for the early diagnosis of clinically significant prostate cancer, re-opens recruitment after lifting of COVID-19 research restrictions A top-ranked research institute in the Northeast US will now partner with Nanostics' by recruiting patients for the clinical validation study This partnership will ...
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